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How to get fromSanibel to Key Largoby bus (Flixbus, Greyhound), car, taxi, plane, shuttle or bus

Find Transport to Key Largo

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There are 6 ways to get from Sanibel to Key Largo by bus (Flixbus, Greyhound), car, taxi, plane, shuttle, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus FlixBus 2421
    2. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus Greyhound US0720s
    6h 8m
    $81–125
  2. Drive 184.7 mi

    cheapest
    1. Drive from Sanibel to Key Largocar car 184.7 mi
    3h 51m
    $34–49
  3. Taxi to Ft. Myers, fly, shuttle

    1. Take the taxi from Sanibel to Ft-Myers-Airport-RSWtaxi taxi
    2. Fly from Ft. Myers (RSW) to Miami International Airport (MIA)plane plane RSW - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    6h 4m
    $183–522
  4. Taxi, bus

    1. Take the taxi from Sanibel to Naples, FLtaxi taxi
    2. Take the bus from Naples, FL to Fort Lauderdale Airportbus bus
    3. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    6h 34m
    $137–283
  5. Bus via Homestead

    1. Take the bus from Fort Myers to Miamibus bus Houston
    2. Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largobus bus 301
    8h 5m
  6. Bus to Tampa, fly, shuttle

    1. Take the bus from Fort Myers 7-11 to Tampa International Airportbus bus
    2. Fly from Tampa (TPA) to Miami International Airport (MIA)plane plane TPA - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    7h 24m
    $251–682

Ft. Myers (RSW) to Miami International Airport (MIA) flights

Calendar92Weekly Planes
Duration5h 39mAverage Duration
Ticket$53Cheapest Price
See schedules

Questions & Answers

What companies run services between Sanibel, FL, USA and Key Largo, FL, USA?

You can take a vehicle from Sanibel to Key Largo Bus Stop via Fort Myers Bus Stop and Miami Airport Station in around 6h 8m.

Airlines
Bus operators
Other operators

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