There are 8 ways to get from Sandestin to Florida Keys by plane, taxi, bus, car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Destin–Fort Walton Beach Airport to Key West International Airport
best- Fly from Destin–Fort Walton Beach Airport (VPS) to Key West International Airport (EYW)plane VPS - EYW
7h 25m$185–618Drive 719.9 mi
cheapest- Drive from Sandestin to Florida Keyscar 719.9 mi
14h 10m$132–190Taxi, bus
- Take the taxi from Sandestin to Whataburger - Defuniak Springstaxi
- Take the bus from Whataburger - Defuniak Springs to Dolphin Mall - Miamibus
- Take the bus from Miami Airport Station to Big Pine Keybus
21h 22m$214–374Drive to Pensacola International Airport, fly to Key West International Airport
- Drive from Sandestin to Pensacola-Airport-PNScar
- Fly from Pensacola International Airport (PNS) to Key West International Airport (EYW)plane PNS - EYW
8h 16m$228–545Fly Destin–Fort Walton Beach Airport to Miami International Airport, shuttle
- Fly from Destin–Fort Walton Beach Airport (VPS) to Miami International Airport (MIA)plane VPS - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
7h 47m$240–583Drive to Pensacola International Airport, fly to Miami International Airport, shuttle
- Drive from Sandestin to Pensacola-Airport-PNScar
- Fly from Pensacola International Airport (PNS) to Miami International Airport (MIA)plane PNS - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
8h 48m$293–750Drive to Pensacola International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Drive from Sandestin to Pensacola-Airport-PNScar
- Fly from Pensacola International Airport (PNS) to Fort Lauderdale–Hollywood International Airport (FLL)plane PNS - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
9h 20m$248–480Taxi, bus via Crestview
- Take the taxi from Sandestin to Crestviewtaxi
- Take the bus from Crestview to Miamibus
- Take the bus from Miami Airport Station to Big Pine Keybus
21h 41m$223–295
Destin–Fort Walton Beach Airport (VPS) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Sandestin to Florida Keys is to drive which costs $130 - $190 and takes 14h 10m.
The fastest way to get from Sandestin to Florida Keys is to fly which takes 7h 25m and costs $180 - $650.
The distance between Sandestin and Florida Keys is 552 miles. The road distance is 724.1 miles.
The best way to get from Sandestin to Florida Keys without a car is to taxi and bus which takes 21h 22m and costs $210 - $380.
It takes approximately 7h 25m to get from Sandestin to Florida Keys, including transfers.
Yes, the driving distance between Sandestin to Florida Keys is 724 miles. It takes approximately 14h 10m to drive from Sandestin to Florida Keys.
There are 827+ hotels available in Florida Keys.
What companies run services between Sandestin, FL, USA and Florida Keys, FL, USA?
American Airlines and Delta fly from Destin–Fort Walton Beach Airport (VPS) to Key West International Airport (EYW) every 4 hours.
- Website
- aa.com
Flights from Destin–Fort Walton Beach Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 57m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–480
Flights from Destin–Fort Walton Beach Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $120–650
Flights from Pensacola International Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $95–550
Flights from Pensacola International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 24m
- When
- Every day
- Estimated price
- $140–750
Flights from Destin–Fort Walton Beach Airport to Miami International Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $50–330
Flights from Pensacola International Airport to Miami International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $60–380
- Website
- delta.com
Flights from Destin–Fort Walton Beach Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $100–550
Flights from Pensacola International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $120–650
Flights from Pensacola International Airport to Miami International Airport via Atlanta
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $80–450
Flights from Pensacola International Airport to Fort Lauderdale–Hollywood International Airport via Atlanta
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $60–340
- Website
- spirit.com
Flights from Pensacola International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 46m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $85–260
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Whataburger - Defuniak Springs to Dolphin Mall - Miami
- Ave. Duration
- 13h 15m
- Frequency
- Once daily
- Estimated price
- $110–240
- Schedules at
- tornadobus.com
- Adults 11-59
- $110–240
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $21–35
- Website
- https://www.greyhound.com/
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $150–200
- Website
- https://www.keysshuttle.com
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Crestview to Miami
- Ave. Duration
- 13h 57m
- Frequency
- Once daily
- Estimated price
- $110–150
- Schedules at
- omnibusexpress.com
- Ave. Duration
- 45 min
- Estimated price
- $80–110
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