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There are 6 ways to get from San Pedro de Atacama to Santa Cruz de la Sierra by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus, train  •  33 h 19 min

  1. Take the bus from San Pedro de Atacama to San Salvador de Jujuy
  2. Take the bus from San Salvador de Jujuy to Fraile Pintado
  3. Take the bus from Fraile Pintado to Salvador Mazza
  4. Take the train from Yacuiba to Santa Cruz de la Sierra - Terminal bimodal

$89 - $111

Cheapest option

Bus Trans Salvador  •  34 h 7 min

  1. Take the bus from San Pedro de Atacama to Calama
  2. Take the bus from Calama to Santa Cruz de la Sierra

$39 - $69

4 alternative options

Bus via Uyuni  •  35 h 30 min

  1. Take the bus from San Pedro de Atacama to Uyuni
  2. Take the bus from Uyuni to Sucre
  3. Take the bus from Sucre to Santa Cruz

$47 - $69

Drive  •  18 h 32 min

  1. Drive from San Pedro de Atacama to Santa Cruz de la Sierra 864.5 miles

$140 - $210

Bus, bus to Uyuni, fly  •  12 h 54 min

  1. Take the bus from San Pedro de Atacama to Calama
  2. Take the bus from Calama to Uyuni
  3. Fly from Uyuni (UYU) to Santa Cruz (VVI) UYU - VVI

$135 - $332

Bus to Salta, fly  •  13 h 42 min

  1. Take the bus from San Pedro de Atacama to Salta
  2. Fly from Salta (SLA) to Santa Cruz (VVI) SLA - VVI

$244 - $1,366

Questions & Answers

The cheapest way to get from San Pedro de Atacama to Santa Cruz de la Sierra is to bus which costs $35 - $70 and takes 34 h 7 min.

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The quickest way to get from San Pedro de Atacama to Santa Cruz de la Sierra is to bus and fly which costs $130 - $340 and takes 12 h 54 min.

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No, there is no direct bus from San Pedro de Atacama to Santa Cruz de la Sierra. However, there are services departing from San Pedro de Atacama and arriving at Santa Cruz de la Sierra via Calama. The journey, including transfers, takes approximately 34 h 7 min.

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The distance between San Pedro de Atacama and Santa Cruz de la Sierra is 773 km. The road distance is 1383.2 km.

Get driving directions

The best way to get from San Pedro de Atacama to Santa Cruz de la Sierra without a car is to bus which takes 34 h 7 min and costs $35 - $70.

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It takes approximately 33 h 19 min to get from San Pedro de Atacama to Santa Cruz de la Sierra, including transfers.

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San Pedro de Atacama to Santa Cruz de la Sierra bus services, operated by Frontera del Norte, depart from San Pedro de Atacama station.

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The quickest flight from Uyuni Airport to Santa Cruz Airport is the direct flight which takes 1 h 15 min.

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San Pedro de Atacama to Santa Cruz de la Sierra bus services, operated by Trans Salvador, arrive at Santa Cruz de la Sierra station.

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Santa Cruz de la Sierra is 1 h behind San Pedro de Atacama. It is currently 8:09 AM in San Pedro de Atacama and 7:09 AM in Santa Cruz de la Sierra.

Map of how to get from San Pedro de Atacama to Santa Cruz de la Sierra.
Launch map view
  • Distance: 483.4 miles
  • Duration: 33 h 19 min

What companies run services between San Pedro de Atacama, Chile and Santa Cruz de la Sierra, Bolivia?

You can take a bus from San Pedro de Atacama to Santa Cruz de la Sierra via Calama and Calama in around 34 h 7 min.

Airlines
Amaszonas
Website
amaszonas.com
Flights from Uyuni to Santa Cruz
Ave. Duration
1 h 15 min
When
Monday, Wednesday and Friday
Estimated price
$110 - $900
Flights from Uyuni to Santa Cruz via La Paz
Ave. Duration
2 h 40 min
When
Monday to Saturday
Estimated price
$110 - $900
Boliviana de Aviación
Website
boa.bo
Flights from Salta to Santa Cruz
Ave. Duration
1 h 30 min
When
Tuesday, Thursday and Saturday
Estimated price
$190 - $1,200
Train operators
Ferroviaria Oriental S.A
Phone
(+591) 3 3387000
Website
fo.com.bo
Train from Yacuiba to Santa Cruz de la Sierra - Terminal bimodal
Ave. Duration
16 h 55 min
Frequency
Once a week
Estimated price
$9
Schedules at
fo.com.bo
Book at
ticketsbolivia.com.bo
Bus operators
Geminis
Phone
(55) 2 892 050 / (55) 2 892 000 / (55) 2 892 04
Email
agencia.calama@geminis.cl
Website
geminis.cl
Bus from San Pedro de Atacama to San Salvador de Jujuy
Ave. Duration
7 h 50 min
Frequency
3 times a week
Estimated price
$59
Schedules at
geminis.cl
Bus from San Pedro de Atacama to Salta
Ave. Duration
9 h 30 min
Frequency
3 times a week
Estimated price
$59
Schedules at
geminis.cl
Andesmar
Phone
1 786 233 7639
Email
gestionesatc@andesmar.com.ar
Website
andesmar.com
Bus from San Pedro de Atacama to San Salvador de Jujuy
Ave. Duration
8 h
Frequency
3 times a week
Estimated price
$16 - $60
Schedules at
andesmar.com
Book at
andesmar.com
Economy
$16 - $24
Executive
$17 - $24
Suite
$24 - $28
Semi Cama
$47
Cama
$57
Flecha Bus
Phone
+54 011 4000 5200
Email
atencionalcliente@flechabus.com.ar
Website
flechabus.com.ar
Bus from Fraile Pintado to Salvador Mazza
Ave. Duration
4 h
Frequency
Twice daily
Estimated price
$15 - $35
Schedules at
centraldepasajes.com.ar
Book at
centraldepasajes.com.ar
Semi Bed
$15 - $21
Suite
$27 - $35
Bed
$15 - $22
Frontera del Norte
Phone
+56 065-280 999 / 9 6633 7480
Website
facebook.com
Bus from San Pedro de Atacama to Calama
Ave. Duration
1 h 30 min
Frequency
Every 3 hours
Estimated price
$4
Schedules at
recorrido.cl
Trans Salvador
Phone
+56 58 222 8547
Email
central@trans-salvador.com
Website
trans-salvador.com
Bus from Calama to Santa Cruz de la Sierra
Ave. Duration
31 h 30 min
Frequency
3 times a week
Estimated price
$35 - $65
Schedules at
trans-salvador.com
Book at
ticketsbolivia.com.bo
Semi Bed
$35 - $50
Premium
$50 - $60
Bus from Calama to Uyuni
Ave. Duration
7 h 30 min
Frequency
Once daily
Estimated price
$11 - $19
Schedules at
trans-salvador.com
Book at
ticketsbolivia.com.bo
Semi Bed
$11 - $16
Premium
$15 - $19
Cruz del Norte
Phone
+56 (9) 82248119
Email
ventas@turisticointernacionalcruzdelnorte.com
Website
turisticointernacionalcruzdelnorte.com
Bus from San Pedro de Atacama to Uyuni
Ave. Duration
13 h
Frequency
Once daily
Estimated price
$18 - $35
Schedules at
turisticointernacionalcruzdelnorte.com
Book at
ticketsbolivia.com.bo
Bus from Calama to Uyuni
Ave. Duration
10 h 30 min
Frequency
Once daily
Estimated price
$13 - $35
Schedules at
turisticointernacionalcruzdelnorte.com
Book at
ticketsbolivia.com.bo
Trans 6 de Octubre
Phone
+591 79576765
Bus from Uyuni to Sucre
Ave. Duration
7 h
Frequency
Once daily
Estimated price
$18
Schedules at
ticketsbolivia.com.bo
Book at
ticketsbolivia.com.bo
Bus from Sucre to Santa Cruz
Ave. Duration
13 h 30 min
Frequency
3 times a day
Estimated price
$19
Schedules at
ticketsbolivia.com.bo
Book at
ticketsbolivia.com.bo
Todo Turismo
Phone
+(591) 2228 7038
Email
atencionalcliente@todoturismosrl.com
Website
todoturismosrl.com
Bus from Uyuni to Sucre Bus Terminal
Ave. Duration
12 h 30 min
Frequency
Once daily
Schedules at
todoturismosrl.com
Book at
todoturismosrl.com
Trans Caminante SRL
Phone
+591 71162388 Santa Cruz / 4 6429385 Sucre
Website
facebook.com
Bus from Sucre to Santa Cruz - Terminal Bimodal
Ave. Duration
13 h 30 min
Frequency
Twice daily
Estimated price
$14
Schedules at
facebook.com
El Mexicano
Phone
+591 67640155
Website
facebook.com
Bus from Sucre to Santa Cruz - Terminal Bimodal
Ave. Duration
13 h
Frequency
Once daily
Estimated price
$15
Schedules at
facebook.com
Flota Bolivar
Phone
+591 2 2281973 La Paz / 4 4221819 Cochabamba / 3 3625458 Santa Cruz / 4 6453849 Sucre / 4 6830856 Yacuiba
Website
facebook.com
Bus from Sucre to Santa Cruz
Ave. Duration
13 h
Frequency
Once daily
Estimated price
$12 - $19
Schedules at
facebook.com
Autotransportes Tupiza
Phone
+591 68421233 Tupiza / 3 3311649 Santa Cruz / 2 6243044 Potosí
Website
facebook.com
Bus from Sucre to Santa Cruz de la Sierra - Terminal Bimodal
Ave. Duration
14 h
Frequency
Once daily
Estimated price
$10 - $13
Schedules at
facebook.com
Atacama 2000
Phone
+ 56 55 31 6664
Bus from Calama to Uyuni
Ave. Duration
8 h 30 min
Frequency
4 times a week
Estimated price
$15
Schedules at
voyhoy.com
Book at
voyhoy.com

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More Questions & Answers

Yes, the driving distance between San Pedro de Atacama to Santa Cruz de la Sierra is 1383 km. It takes approximately 18 h 32 min to drive from San Pedro de Atacama to Santa Cruz de la Sierra.

Get driving directions

Amaszonas offers flights from Uyuni Airport to Santa Cruz Airport.

Search flights

There are 239+ hotels available in Santa Cruz de la Sierra. Prices start at $26 USD per night.

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