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There are 10 ways to get from San Diego to South Carolina by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Greenville/Spartanburg  •  7 h 21 min

  1. Fly from San Diego (SAN) to Greenville/Spartanburg (GSP) SAN - GSP

$272 - $998

Cheapest option

Fly to Charlotte, bus  •  8 h 26 min

  1. Fly from San Diego (SAN) to Charlotte (CLT) SAN - CLT
  2. Take the bus from Transit Center- Bay X to White Street Park and Ride

$168 - $610

8 alternative options

Fly to Columbia  •  7 h 29 min

  1. Fly from San Diego (SAN) to Columbia (CAE) SAN - CAE

$286 - $2,032

Fly to Florence  •  8 h 28 min

  1. Fly from San Diego (SAN) to Florence (FLO) SAN - FLO

$340 - $1,314

Fly to Charleston  •  8 h 37 min

  1. Fly from San Diego (SAN) to Charleston (CHS) SAN - CHS

$304 - $1,106

Bus  •  2 days 10 h

  1. Take the bus from San Diego, Ca to Los Angeles, Ca
  2. Take the bus from Los Angeles, Ca to Dallas, Tx
  3. Take the bus from Dallas, Tx to Atlanta, Ga
  4. Take the bus from Atlanta, GA to Florence, SC

$266 - $644

Bus via San Antonio  •  2 days 13 h

  1. Take the bus from San Diego to San Antonio
  2. Take the bus from San Antonio to Houston Downtown Greyhound
  3. Take the bus from Houston, Tx to Atlanta, Ga
  4. Take the bus from Atlanta, Ga to Florence, SC

Train  •  3 days 0 h

  1. Take the train from San Diego Santa Fe Depot to Fullerton Amtrak Station
  2. Take the train from Fullerton Amtrak Station to Chicago Union Station
  3. Take the train from Chicago Union Station to Washington Union Station
  4. Take the train from Washington Union Station to Florence Amtrak Station

$465 - $1,405

Train via New Orleans Union Passenger Terminal  •  3 days 5 h

  1. Take the train from San Diego Santa Fe Depot to Los Angeles Union Station
  2. Take the train from Los Angeles Union Station to New Orleans Union Passenger Terminal
  3. Take the train from New Orleans Union Passenger Terminal to Greensboro Amtrak Station
  4. Take the train from Greensboro Amtrak Station to Selma-Smithfield Amtrak Station
  5. Take the train from Selma-Smithfield Amtrak Station to Florence Amtrak Station

$443 - $1,309

Drive  •  39 h 26 min

  1. Drive from San Diego to Florence 2444.3 miles

$230 - $350

Questions & Answers

The cheapest way to get from San Diego to South Carolina is to fly and bus which costs $160 - $650 and takes 8 h 26 min.

More details

The quickest way to get from San Diego to South Carolina is to fly which costs $270 - $1,000 and takes 7 h 21 min.

More details

No, there is no direct bus from San Diego to South Carolina. However, there are services departing from San Diego, Ca and arriving at Florence, SC via Los Angeles, Ca, Dallas, Tx, Peachtree St @ Alabama St and Atlanta, GA. The journey, including transfers, takes approximately 2 days 10 h.

More details

No, there is no direct train from San Diego to South Carolina station. However, there are services departing from San Diego Santa Fe Depot and arriving at Florence Amtrak Station via Fullerton Amtrak Station, Chicago Union Station and Washington Union Station. The journey, including transfers, takes approximately 3 days 0 h.

More details

The distance between San Diego and South Carolina is 2125 miles. The road distance is 2444.3 miles.

Get driving directions

The best way to get from San Diego to South Carolina without a car is to bus which takes 2 days 10 h and costs $260 - $650.

More details

It takes approximately 7 h 21 min to get from San Diego to South Carolina, including transfers.

More details

San Diego to South Carolina bus services, operated by Greyhound USA, depart from San Diego, Ca station.

More details

San Diego to South Carolina train services, operated by Amtrak, depart from San Diego Santa Fe Depot station.

More details

The best way to get from San Diego to South Carolina is to fly which takes 7 h 21 min and costs $270 - $1,000. Alternatively, you can bus, which costs $260 - $650 and takes 2 days 10 h, you could also train, which costs $460 - $1,400 and takes 3 days 0 h.

Mode details

Map of how to get from San Diego to South Carolina.
Launch map view
  • Distance: 2125.4 miles
  • Duration: 7 h 21 min

What companies run services between San Diego, CA, USA and South Carolina, USA?

Southwest Airlines, Delta and two other airlines fly from San Diego to Greenville hourly. Alternatively, you can take a bus from San Diego to Florence via Los Angeles, Ca, Dallas, Tx, Atlanta, Ga, Peachtree St @ Alabama St, Peachtree St Sw @ Brotherton Transportation Mall, and Atlanta, GA in around 2 days 10 h.

Airlines
American Airlines
Website
aa.com
Flights from San Diego to Greenville/Spartanburg via Dallas/Ft.Worth
Ave. Duration
6 h 15 min
When
Monday, Thursday, Friday, Saturday and Sunday
Estimated price
$240 - $950
Flights from San Diego to Greenville/Spartanburg via Charlotte
Ave. Duration
7 h 21 min
When
Every day
Estimated price
$250 - $950
Flights from San Diego to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
7 h 47 min
When
Monday, Tuesday, Wednesday, Thursday, Saturday and Sunday
Estimated price
$260 - $950
Flights from San Diego to Columbia via Dallas/Ft.Worth
Ave. Duration
6 h 14 min
When
Every day
Estimated price
$290 - $1,100
Flights from San Diego to Columbia via Charlotte
Ave. Duration
7 h 40 min
When
Every day
Estimated price
$300 - $1,100
Flights from San Diego to Columbia via Philadelphia
Ave. Duration
10 h 34 min
When
Every day
Estimated price
$360 - $1,300
Flights from San Diego to Columbia via Phoenix, Charlotte
Ave. Duration
7 h 55 min
When
Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$300 - $1,100
Flights from San Diego to Florence via Charlotte
Ave. Duration
8 h 17 min
When
Every day
Estimated price
$330 - $1,300
Flights from San Diego to Florence via Dallas/Ft.Worth, Charlotte
Ave. Duration
9 h 16 min
When
Tuesday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$340 - $1,300
Flights from San Diego to Florence via Los Angeles, Charlotte
Ave. Duration
10 h 3 min
When
Every day
Estimated price
$350 - $1,300
Flights from San Diego to Florence via Phoenix, Charlotte
Ave. Duration
10 h 22 min
When
Every day
Estimated price
$330 - $1,300
Flights from San Diego to Charleston via Dallas/Ft.Worth
Ave. Duration
6 h 50 min
When
Every day
Estimated price
$300 - $1,100
Flights from San Diego to Charleston via Charlotte
Ave. Duration
7 h 17 min
When
Monday, Tuesday, Wednesday, Thursday and Sunday
Estimated price
$300 - $1,100
Flights from San Diego to Charlotte
Ave. Duration
4 h 32 min
When
Every day
Estimated price
$210 - $1,100
Flights from San Diego to Charlotte via Phoenix
Ave. Duration
6 h 10 min
When
Every day
Estimated price
$210 - $1,100
Flights from San Diego to Charlotte via Los Angeles
Ave. Duration
6 h 20 min
When
Every day
Estimated price
$210 - $1,100
Flights from San Diego to Charlotte via Dallas/Ft.Worth
Ave. Duration
6 h 24 min
When
Every day
Estimated price
$210 - $1,100
Delta
Website
delta.com
Flights from San Diego to Greenville/Spartanburg via Atlanta
Ave. Duration
6 h 42 min
When
Every day
Estimated price
$230 - $950
Flights from San Diego to Greenville/Spartanburg via Detroit
Ave. Duration
7 h 44 min
When
Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$250 - $1,100
Flights from San Diego to Columbia via Atlanta
Ave. Duration
6 h 45 min
When
Every day
Estimated price
$270 - $1,200
Flights from San Diego to Columbia via Las Vegas, Atlanta
Ave. Duration
7 h 51 min
When
Thursday
Estimated price
$280 - $1,200
Flights from San Diego to Columbia via Los Angeles, Atlanta
Ave. Duration
8 h 5 min
When
Saturday
Estimated price
$280 - $1,200
Flights from San Diego to Charleston via Atlanta
Ave. Duration
6 h 57 min
When
Every day
Estimated price
$270 - $1,200
Flights from San Diego to Charlotte via Atlanta
Ave. Duration
6 h 29 min
When
Saturday and Sunday
Estimated price
$210 - $1,200
United Airlines
Website
united.com
Flights from San Diego to Greenville/Spartanburg via Houston
Ave. Duration
6 h 33 min
When
Every day
Estimated price
$250 - $1,100
Flights from San Diego to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
7 h 17 min
When
Every day
Estimated price
$260 - $1,100
Flights from San Diego to Greenville/Spartanburg via Washington Dulles
Ave. Duration
7 h 44 min
When
Monday, Tuesday, Thursday, Friday and Sunday
Estimated price
$280 - $1,100
Flights from San Diego to Greenville/Spartanburg via Newark
Ave. Duration
8 h 12 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$300 - $1,200
Flights from San Diego to Columbia via Chicago O'Hare
Ave. Duration
7 h 6 min
When
Every day
Estimated price
$380 - $4,000
Flights from San Diego to Columbia via Houston
Ave. Duration
7 h 2 min
When
Every day
Estimated price
$380 - $4,000
Flights from San Diego to Columbia via Washington Dulles
Ave. Duration
7 h 37 min
When
Every day
Estimated price
$380 - $4,000
Flights from San Diego to Charleston via Houston
Ave. Duration
6 h 38 min
When
Every day
Estimated price
$300 - $1,300
Flights from San Diego to Charleston via Chicago O'Hare
Ave. Duration
7 h 26 min
When
Tuesday
Estimated price
$320 - $1,300
Flights from San Diego to Charleston via Washington Dulles
Ave. Duration
7 h 52 min
When
Every day
Estimated price
$330 - $1,300
Flights from San Diego to Charlotte via Denver
Ave. Duration
6 h 20 min
When
Saturday
Estimated price
$210 - $1,300
Southwest Airlines
Website
southwest.com
Flights from San Diego to Greenville/Spartanburg via Atlanta
Ave. Duration
6 h 3 min
When
Every day
Estimated price
$280 - $1,000
Flights from San Diego to Charleston via Denver
Ave. Duration
6 h 25 min
When
Sunday
Estimated price
$350 - $1,200
Flights from San Diego to Charleston via Houston Hobby Apt
Ave. Duration
6 h 25 min
When
Wednesday, Thursday and Friday
Estimated price
$350 - $1,200
Flights from San Diego to Charleston via Chicago Midway
Ave. Duration
6 h 53 min
When
Wednesday, Saturday and Sunday
Estimated price
$370 - $1,300
Flights from San Diego to Charleston via Baltimore
Ave. Duration
7 h 35 min
When
Wednesday
Estimated price
$400 - $1,400
Flights from San Diego to Charleston via Nashville
Ave. Duration
7 h 55 min
When
Wednesday
Estimated price
$340 - $1,200
Flights from San Diego to Charlotte via Nashville
Ave. Duration
5 h 50 min
When
Sunday
Estimated price
$280 - $1,300
Flights from San Diego to Charlotte via Dallas
Ave. Duration
6 h 15 min
When
Wednesday, Thursday, Friday and Sunday
Estimated price
$280 - $1,300
Flights from San Diego to Charlotte via Chicago Midway
Ave. Duration
6 h 25 min
When
Wednesday
Estimated price
$280 - $1,300
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from San Diego Santa Fe Depot to Fullerton Amtrak Station
Ave. Duration
2 h 22 min
Frequency
Every 2 hours
Estimated price
$30 - $65
Website
amtrak.com
Coach Seat
$30 - $45
Flexi Coach Seat
$50 - $80
Business Coach Seat
$45 - $65
Room
$160 - $220
Train from Fullerton Amtrak Station to Chicago Union Station
Ave. Duration
42 h 15 min
Frequency
Once daily
Estimated price
$270 - $850
Website
amtrak.com
Coach Seat
$270 - $400
Flexi Coach Seat
$480 - $700
Business Coach Seat
$550 - $850
Room
$1,000 - $1,400
Train from Chicago Union Station to Washington Union Station
Ave. Duration
17 h 25 min
Frequency
Once daily
Estimated price
$100 - $310
Website
amtrak.com
Coach Seat
$100 - $160
Flexi Coach Seat
$190 - $280
Business Coach Seat
$220 - $310
Room
$440 - $600
Train from Washington Union Station to Florence Amtrak Station
Ave. Duration
7 h 40 min
Frequency
Twice daily
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$280 - $400
Train from San Diego Santa Fe Depot to Los Angeles Union Station
Ave. Duration
2 h 58 min
Frequency
Every 2 hours
Estimated price
$30 - $75
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$55 - $85
Business Coach Seat
$50 - $75
Room
$170 - $240
Train from Los Angeles Union Station to New Orleans Union Passenger Terminal
Ave. Duration
45 h 40 min
Frequency
3 times a week
Estimated price
$240 - $750
Website
amtrak.com
Coach Seat
$240 - $360
Flexi Coach Seat
$440 - $650
Business Coach Seat
$500 - $750
Room
$900 - $1,300
Train from New Orleans Union Passenger Terminal to Greensboro Amtrak Station
Ave. Duration
19 h 37 min
Frequency
Once daily
Estimated price
$110 - $340
Website
amtrak.com
Coach Seat
$110 - $180
Flexi Coach Seat
$210 - $300
Business Coach Seat
$240 - $340
Room
$470 - $650
Train from Greensboro Amtrak Station to Selma-Smithfield Amtrak Station
Ave. Duration
2 h 22 min
Frequency
Once daily
Estimated price
$30 - $70
Website
amtrak.com
Coach Seat
$30 - $45
Flexi Coach Seat
$55 - $80
Business Coach Seat
$45 - $70
Room
$160 - $230
Train from Selma-Smithfield Amtrak Station to Florence Amtrak Station
Ave. Duration
2 h 25 min
Frequency
Once daily
Estimated price
$30 - $75
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$55 - $85
Business Coach Seat
$50 - $75
Room
$170 - $240
Bus operators
Charlotte Area Transit System
Phone
+1 704-336-7433
Email
telltransit@charlottenc.gov
Website
charlottenc.gov
Bus from Transit Center- Bay X to White Street Park and Ride
Ave. Duration
1 h 12 min
Frequency
3 times a day
Estimated price
$3 - $5
Schedules at
charlottenc.gov
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from San Diego, Ca to Los Angeles, Ca
Ave. Duration
3 h 20 min
Frequency
Hourly
Estimated price
$18 - $45
Website
greyhound.com
Economy
$18 - $27
Flexible
$30 - $45
Bus from Los Angeles, Ca to Dallas, Tx
Ave. Duration
29 h 20 min
Frequency
Every 4 hours
Estimated price
$130 - $340
Website
greyhound.com
Economy
$130 - $220
Flexible
$250 - $340
Bus from Dallas, Tx to Atlanta, Ga
Ave. Duration
17 h 30 min
Frequency
4 times a day
Estimated price
$80 - $200
Website
greyhound.com
Economy
$80 - $130
Flexible
$150 - $200
Bus from Houston, Tx to Atlanta, Ga
Ave. Duration
16 h 55 min
Frequency
Every 2 hours
Estimated price
$75 - $200
Website
greyhound.com
Economy
$75 - $130
Flexible
$150 - $200
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Atlanta, GA to Florence, SC
Ave. Duration
5 h 30 min
Frequency
Once daily
Estimated price
$35 - $60
Schedules at
southeasternstages.com
Bus from Atlanta, Ga to Florence, SC
Ave. Duration
6 h 55 min
Frequency
3 times a day
Estimated price
$40 - $65
Schedules at
southeasternstages.com
Greyhound Mexico
Phone
01-800 890 6821
Website
greyhound.com.mx
Bus from San Diego to San Antonio
Ave. Duration
30 h
Frequency
Every 2 hours
Estimated price
$110 - $180
Schedules at
greyhound.com.mx
Turimex Internacional
Website
turimex.com
Bus from San Antonio to Houston Downtown Greyhound
Ave. Duration
4 h
Frequency
4 times a day
Schedules at
turimex.com

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More Questions & Answers

There is no direct flight from San Diego Airport to Greenville/Spartanburg Airport. The quickest flight takes 5 h 55 min and has one stopover.

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San Diego to South Carolina bus services, operated by South Eastern Stages, arrive at Florence, SC station.

More details

South Carolina is 3 h ahead of San Diego. It is currently 9:27 PM in San Diego and 12:27 AM in South Carolina.

San Diego to South Carolina train services, operated by Amtrak, arrive at Florence Amtrak Station.

More details

Yes, the driving distance between San Diego to South Carolina is 2444 miles. It takes approximately 39 h 26 min to drive from San Diego to South Carolina.

Get driving directions

Southwest Airlines, American Airlines, United Airlines and Delta offer flights from San Diego Airport to Greenville/Spartanburg Airport.

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Book your San Diego to South Carolina train tickets online with Rome2rio.

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There are 19+ hotels available in South Carolina. Prices start at $49 USD per night.

More details

The best way to get from San Diego to San Diego Airport is to line 992 bus which takes 9 min and costs $2 - $3.

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