There are 10 ways to get from San Diego to South Carolina by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Charlotte  •  6 h 13 min

  1. Fly from San Diego (SAN) to Charlotte (CLT) SAN - CLT

$237 - $692

9 alternative options

Fly to Greenville/Spartanburg  •  7 h 16 min

  1. Fly from San Diego (SAN) to Greenville/Spartanburg (GSP) SAN - GSP

$272 - $998

Fly to Columbia  •  7 h 59 min

  1. Fly from San Diego (SAN) to Columbia (CAE) SAN - CAE

$286 - $2,032

Fly to Florence  •  8 h 38 min

  1. Fly from San Diego (SAN) to Florence (FLO) SAN - FLO

$340 - $1,314

Fly to Charleston  •  8 h 35 min

  1. Fly from San Diego (SAN) to Charleston (CHS) SAN - CHS

$304 - $1,106

Bus  •  2 days 7 h

  1. Take the bus from San Diego, Ca to San Bernardino, Ca
  2. Take the bus from San Bernardino, Ca to Dallas, Tx
  3. Take the bus from Dallas, Tx to Atlanta, Ga
  4. Take the bus from Atlanta, GA to Florence, SC

$255 - $621

Bus via San Antonio, Tx  •  2 days 10 h

  1. Take the bus from San Diego to San Antonio
  2. Take the bus from San Antonio, Tx to Houston, Tx
  3. Take the bus from Houston, Tx to Atlanta, Ga
  4. Take the bus from Atlanta, Ga to Florence, SC

$254 - $504

Train  •  3 days 0 h

  1. Take the train from San Diego Santa Fe Depot to Fullerton Transportation Center
  2. Take the train from Fullerton Transportation Center to Chicago Union Station
  3. Take the train from Chicago Union Station to Washington Union Station
  4. Take the train from Washington Union Station to Florence Amtrak

$465 - $1,405

Train, bus  •  3 days 4 h

  1. Take the train from San Diego Santa Fe Depot to Los Angeles Union Station Amtrak
  2. Take the train from Los Angeles Union Station Amtrak to New Orleans Union Passenger Terminal
  3. Take the train from New Orleans Union Passenger Terminal to Greensboro Galyon Transportation Center
  4. Take the bus from Greensboro, Nc to Raleigh, Nc
  5. Take the bus from Raleigh, Nc to Florence, Sc

$417 - $1,249

Drive  •  39 h 26 min

  1. Drive from San Diego to Florence 2444.3 miles

$230 - $350

Questions & Answers

The cheapest way to get from San Diego to South Carolina is to drive which costs $230 - $350 and takes 39 h 26 min.

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The quickest way to get from San Diego to South Carolina is to fly which costs $230 - $700 and takes 6 h 13 min.

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No, there is no direct bus from San Diego to South Carolina. However, there are services departing from San Diego, Ca and arriving at Florence, SC via San Bernardino, Ca, Dallas, Tx, Peachtree St @ Alabama St and Atlanta, GA. The journey, including transfers, takes approximately 2 days 7 h.

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No, there is no direct train from San Diego to South Carolina. However, there are services departing from San Diego Santa Fe Depot and arriving at Florence Amtrak via Fullerton Transportation Center, Chicago Union Station and Washington Union Station. The journey, including transfers, takes approximately 3 days 0 h.

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The distance between San Diego and South Carolina is 2125 miles. The road distance is 2444.3 miles.

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The best way to get from San Diego to South Carolina without a car is to bus which takes 2 days 7 h and costs $250 - $650.

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It takes approximately 6 h 13 min to get from San Diego to South Carolina, including transfers.

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San Diego to South Carolina bus services, operated by Greyhound USA, depart from San Diego, Ca station.

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San Diego to South Carolina train services, operated by Amtrak, depart from San Diego Santa Fe Depot station.

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The best way to get from San Diego to South Carolina is to fly which takes 6 h 13 min and costs $230 - $700. Alternatively, you can bus, which costs $250 - $650 and takes 2 days 7 h, you could also train, which costs $460 - $1,400 and takes 3 days 0 h.

Mode details

Map of how to get from San Diego to South Carolina.
Launch map view
  • Distance: 2125.4 miles
  • Duration: 6 h 13 min

What companies run services between San Diego, CA, USA and South Carolina, USA?

American Airlines, Southwest Airlines and three other airlines fly from San Diego to Rock Hill hourly. Alternatively, you can take a bus from San Diego to Florence via San Bernardino, Ca, Dallas, Tx, Atlanta, Ga, Peachtree St @ Alabama St, Peachtree St Sw @ Brotherton Transportation Mall, and Atlanta, GA in around 2 days 7 h.

Airlines
American Airlines
Website
aa.com
Flights from San Diego to Charlotte
Ave. Duration
4 h 42 min
When
Every day
Estimated price
$210 - $1,100
Flights from San Diego to Charlotte via Phoenix
Ave. Duration
6 h 15 min
When
Every day
Estimated price
$210 - $1,100
Flights from San Diego to Charlotte via Dallas/Ft.Worth
Ave. Duration
6 h 36 min
When
Every day
Estimated price
$210 - $1,100
Flights from San Diego to Charlotte via Los Angeles
Ave. Duration
6 h 40 min
When
Every day
Estimated price
$210 - $1,100
Flights from San Diego to Greenville/Spartanburg via Dallas/Ft.Worth
Ave. Duration
6 h 38 min
When
Every day
Estimated price
$240 - $950
Flights from San Diego to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
7 h 25 min
When
Every day
Estimated price
$260 - $950
Flights from San Diego to Greenville/Spartanburg via Charlotte
Ave. Duration
7 h 29 min
When
Every day
Estimated price
$250 - $950
Flights from San Diego to Greenville/Spartanburg via Philadelphia
Ave. Duration
9 h 1 min
When
Every day
Estimated price
$300 - $1,100
Flights from San Diego to Columbia via Dallas/Ft.Worth
Ave. Duration
6 h 43 min
When
Every day
Estimated price
$290 - $1,100
Flights from San Diego to Columbia via Charlotte
Ave. Duration
7 h 44 min
When
Every day
Estimated price
$300 - $1,100
Flights from San Diego to Columbia via Philadelphia
Ave. Duration
9 h 12 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$360 - $1,300
Flights from San Diego to Florence via Charlotte
Ave. Duration
7 h 44 min
When
Every day
Estimated price
$330 - $1,300
Flights from San Diego to Florence via Los Angeles, Charlotte
Ave. Duration
9 h 25 min
When
Every day
Estimated price
$350 - $1,300
Flights from San Diego to Florence via Dallas/Ft.Worth, Charlotte
Ave. Duration
9 h 36 min
When
Every day
Estimated price
$340 - $1,300
Flights from San Diego to Florence via Chicago O'Hare, Charlotte
Ave. Duration
10 h 20 min
When
Every day
Estimated price
$360 - $1,300
Flights from San Diego to Florence via Phoenix, Charlotte
Ave. Duration
11 h 19 min
When
Every day
Estimated price
$330 - $1,300
Flights from San Diego to Charleston via Dallas/Ft.Worth
Ave. Duration
6 h 23 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$300 - $1,100
Flights from San Diego to Charleston via Charlotte
Ave. Duration
7 h 54 min
When
Every day
Estimated price
$300 - $1,100
Flights from San Diego to Charleston via Chicago O'Hare
Ave. Duration
8 h 49 min
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$320 - $1,200
Delta
Website
delta.com
Flights from San Diego to Charlotte via Atlanta
Ave. Duration
6 h 40 min
When
Every day
Estimated price
$210 - $1,200
Flights from San Diego to Greenville/Spartanburg via Atlanta
Ave. Duration
7 h 7 min
When
Every day
Estimated price
$230 - $950
Flights from San Diego to Greenville/Spartanburg via Detroit
Ave. Duration
8 h 24 min
When
Every day
Estimated price
$250 - $1,100
Flights from San Diego to Columbia via Atlanta
Ave. Duration
7 h 20 min
When
Every day
Estimated price
$270 - $1,200
Flights from San Diego to Charleston via Atlanta
Ave. Duration
7 h 20 min
When
Every day
Estimated price
$270 - $1,200
United Airlines
Website
united.com
Flights from San Diego to Greenville/Spartanburg via Houston
Ave. Duration
6 h 19 min
When
Every day
Estimated price
$250 - $1,100
Flights from San Diego to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
8 h 10 min
When
Every day
Estimated price
$260 - $1,100
Flights from San Diego to Greenville/Spartanburg via Washington Dulles
Ave. Duration
8 h 14 min
When
Every day
Estimated price
$280 - $1,100
Flights from San Diego to Columbia via Houston
Ave. Duration
7 h 4 min
When
Every day
Estimated price
$380 - $4,000
Flights from San Diego to Columbia via Chicago O'Hare
Ave. Duration
7 h 12 min
When
Every day
Estimated price
$380 - $4,000
Flights from San Diego to Columbia via Washington Dulles
Ave. Duration
7 h 38 min
When
Every day
Estimated price
$380 - $4,000
Flights from San Diego to Charleston via Houston
Ave. Duration
6 h 28 min
When
Every day
Estimated price
$300 - $1,300
Flights from San Diego to Charleston via Chicago O'Hare
Ave. Duration
7 h 57 min
When
Every day
Estimated price
$320 - $1,300
Flights from San Diego to Charleston via Washington Dulles
Ave. Duration
7 h 52 min
When
Every day
Estimated price
$330 - $1,300
Flights from San Diego to Charleston via Newark
Ave. Duration
8 h 22 min
When
Monday to Saturday
Estimated price
$350 - $1,400
Southwest Airlines
Website
southwest.com
Flights from San Diego to Charlotte via Nashville
Ave. Duration
6 h 7 min
When
Monday to Saturday
Estimated price
$280 - $1,300
Flights from San Diego to Charlotte via Chicago Midway
Ave. Duration
6 h 35 min
When
Sunday
Estimated price
$280 - $1,300
Flights from San Diego to Charlotte via Houston Hobby Apt
Ave. Duration
6 h 40 min
When
Sunday
Estimated price
$280 - $1,300
Flights from San Diego to Greenville/Spartanburg via Atlanta
Ave. Duration
5 h 53 min
When
Every day
Estimated price
$280 - $1,000
Flights from San Diego to Charleston via Denver
Ave. Duration
6 h 25 min
When
Sunday
Estimated price
$350 - $1,200
Flights from San Diego to Charleston via Houston Hobby Apt
Ave. Duration
6 h 40 min
When
Monday to Saturday
Estimated price
$350 - $1,200
Flights from San Diego to Charleston via Chicago Midway
Ave. Duration
7 h 8 min
When
Every day
Estimated price
$370 - $1,300
Frontier Airlines
Website
flyfrontier.com
Flights from San Diego to Charlotte via Denver
Ave. Duration
6 h 31 min
When
Every day
Estimated price
$170 - $800
JetBlue Airways
Website
jetblue.com
Flights from San Diego to Charleston via New York JFK
Ave. Duration
8 h 30 min
When
Every day
Estimated price
$370 - $1,400
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from San Diego Santa Fe Depot to Fullerton Transportation Center
Ave. Duration
2 h 14 min
Frequency
Every 2 hours
Estimated price
$30 - $65
Website
amtrak.com
Coach Seat
$30 - $45
Flexi Coach Seat
$50 - $80
Business Coach Seat
$45 - $65
Room
$160 - $220
Train from Fullerton Transportation Center to Chicago Union Station
Ave. Duration
42 h 15 min
Frequency
Twice daily
Estimated price
$270 - $850
Website
amtrak.com
Coach Seat
$270 - $400
Flexi Coach Seat
$480 - $700
Business Coach Seat
$550 - $850
Room
$1,000 - $1,400
Train from Chicago Union Station to Washington Union Station
Ave. Duration
17 h 25 min
Frequency
Once daily
Estimated price
$100 - $310
Website
amtrak.com
Coach Seat
$100 - $160
Flexi Coach Seat
$190 - $280
Business Coach Seat
$220 - $310
Room
$440 - $600
Train from Washington Union Station to Florence Amtrak
Ave. Duration
7 h 40 min
Frequency
Twice daily
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$280 - $400
Train from San Diego Santa Fe Depot to Los Angeles Union Station Amtrak
Ave. Duration
2 h 59 min
Frequency
Every 2 hours
Estimated price
$30 - $75
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$55 - $85
Business Coach Seat
$50 - $75
Room
$170 - $240
Train from Los Angeles Union Station Amtrak to New Orleans Union Passenger Terminal
Ave. Duration
45 h 40 min
Frequency
3 times a week
Estimated price
$240 - $750
Website
amtrak.com
Coach Seat
$240 - $360
Flexi Coach Seat
$440 - $650
Business Coach Seat
$500 - $750
Room
$900 - $1,300
Train from New Orleans Union Passenger Terminal to Greensboro Galyon Transportation Center
Ave. Duration
19 h 37 min
Frequency
Once daily
Estimated price
$110 - $340
Website
amtrak.com
Coach Seat
$110 - $180
Flexi Coach Seat
$210 - $300
Business Coach Seat
$240 - $340
Room
$470 - $650
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from San Diego, Ca to San Bernardino, Ca
Ave. Duration
2 h 30 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $25
Flexible
$30 - $40
Bus from San Bernardino, Ca to Dallas, Tx
Ave. Duration
27 h 50 min
Frequency
Hourly
Estimated price
$120 - $320
Website
greyhound.com
Economy
$120 - $210
Flexible
$240 - $320
Bus from Dallas, Tx to Atlanta, Ga
Ave. Duration
17 h 30 min
Frequency
Hourly
Estimated price
$80 - $200
Website
greyhound.com
Economy
$80 - $130
Flexible
$150 - $200
Bus from San Antonio, Tx to Houston, Tx
Ave. Duration
3 h 15 min
Frequency
Hourly
Estimated price
$24 - $60
Website
greyhound.com
Economy
$24 - $40
Flexible
$45 - $60
Bus from Houston, Tx to Atlanta, Ga
Ave. Duration
16 h 55 min
Frequency
Every 30 minutes
Estimated price
$75 - $200
Website
greyhound.com
Economy
$75 - $130
Flexible
$150 - $200
Bus from Greensboro, Nc to Raleigh, Nc
Ave. Duration
1 h 45 min
Frequency
Hourly
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Bus from Raleigh, Nc to Florence, Sc
Ave. Duration
3 h 30 min
Frequency
Every 30 minutes
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Atlanta, GA to Florence, SC
Ave. Duration
5 h 30 min
Frequency
Once daily
Estimated price
$35 - $60
Schedules at
southeasternstages.com
Bus from Atlanta, Ga to Florence, SC
Ave. Duration
6 h 55 min
Frequency
3 times a day
Estimated price
$40 - $65
Schedules at
southeasternstages.com
Greyhound Mexico
Phone
01-800 890 6821
Website
greyhound.com.mx
Bus from San Diego to San Antonio
Ave. Duration
30 h
Frequency
5 times a day
Estimated price
$110 - $180
Schedules at
greyhound.com.mx

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More Questions & Answers

The quickest flight from San Diego Airport to Charlotte Airport is the direct flight which takes 4 h 31 min.

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San Diego to South Carolina bus services, operated by South Eastern Stages, arrive at Florence, SC station.

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South Carolina is 3 h ahead of San Diego. It is currently 8:25 PM in San Diego and 11:25 PM in South Carolina.

San Diego to South Carolina train services, operated by Amtrak, arrive at Florence Amtrak station.

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Yes, the driving distance between San Diego to South Carolina is 2444 miles. It takes approximately 39 h 26 min to drive from San Diego to South Carolina.

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Frontier Airlines, Delta, Southwest Airlines and American Airlines offer flights from San Diego Airport to Charlotte Airport.

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Book your San Diego to South Carolina train tickets online with Rome2rio.

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There are 16+ hotels available in South Carolina. Prices start at $52 USD per night.

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The best way to get from San Diego to San Diego Airport is to line 992 bus which takes 9 min and costs $2 - $3.

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