There are 8 ways to get from San Diego to Palo Alto by plane, train, subway, bus, night bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to San Jose, Caltrain  •  3 h 38 min

  1. Fly from San Diego (SAN) to San Jose (SJC) SAN - SJC
  2. Take the Caltrain from Santa Clara Caltrain to California Ave Caltrain

$82 - $339

Cheapest option

Bus Tufesa  •  14 h 53 min

  1. Take the bus from San Diego, CA to Anaheim Tufesa
  2. Take the bus from Anaheim to San Jose, CA Tufesa

$36 - $88

6 alternative options

Fly to San Francisco  •  4 h 1 min

  1. Fly from San Diego (SAN) to San Francisco (SFO) SAN - SFO

$80 - $325

Fly to Oakland, BART, bus  •  4 h 37 min

  1. Fly from San Diego (SAN) to Oakland (OAK) SAN - OAK
  2. Take the BART from Coliseum to Union City
  3. Take the bus from Union City BART to Middlefield Rd:Willow Rd

$95 - $367

Bus Greyhound USA  •  10 h 31 min

  1. Take the bus from San Diego, Ca to Los Angeles, Ca 9486 / ...
  2. Take the bus from Los Angeles, Ca to San Jose, Ca 6860 / ...

$57 - $136

Train  •  14 h 47 min

  1. Take the train from San Diego Santa Fe Depot Amtrak to Los Angeles Union Station Amtrak Pacific Surfliner
  2. Take the train from Los Angeles Union Station Amtrak to San Jose Diridon Station Amtrak Coast Starlight

$102 - $260

Bus, night bus  •  10 h 52 min

  1. Take the bus from San Diego, Ca to Los Angeles, Ca 9486 / ...
  2. Take the night bus from Los Angeles, Ca to San Jose, Ca 6876

$57 - $136

Drive  •  8 h 4 min

  1. Drive from San Diego to Palo Alto 479.2 miles

$45 - $70

What companies run services between San Diego, CA, USA and Palo Alto, CA, USA?

Alaska Airlines, Inc., Virgin America and two other airlines fly from San Diego to Palo Alto hourly. Alternatively, you can take a bus from San Diego to Palo Alto via Los Angeles, Ca, San Jose, Ca, and San Jose Diridon Caltrain in around 10 h 31 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from San Diego to San Jose
Ave. Duration
1 h 22 min
When
Every day
Estimated price
$140 - $650
Flights from San Diego to San Francisco
Ave. Duration
1 h 34 min
When
Every day
Estimated price
$150 - $650
Flights from San Diego to Oakland
Ave. Duration
1 h 29 min
When
Every day
Estimated price
$150 - $700
Alaska Airlines, Inc.
Website
alaskaair.com
Flights from San Diego to San Jose
Ave. Duration
1 h 33 min
When
Every day
Estimated price
$80 - $500
Flights from San Diego to San Francisco
Ave. Duration
1 h 32 min
When
Every day
Estimated price
$120 - $550
United Airlines
Website
united.com
Flights from San Diego to San Francisco
Ave. Duration
1 h 36 min
When
Every day
Estimated price
$110 - $550
Virgin America
Website
virginamerica.com
Flights from San Diego to San Francisco
Ave. Duration
1 h 32 min
When
Every day
Estimated price
$120 - $550
Train operators
Caltrain
Website
caltrain.com
Train from Santa Clara Caltrain to California Ave Caltrain
Ave. Duration
23 min
Frequency
Every 30 minutes
Estimated price
$3 - $5
Schedules at
caltrain.com
BART
Website
bart.gov
Subway from Coliseum to Union City
Ave. Duration
21 min
Frequency
Every 15 minutes
Estimated price
$3 - $5
Schedules at
bart.gov
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from San Diego Santa Fe Depot Amtrak to Los Angeles Union Station Amtrak
Ave. Duration
2 h 59 min
Frequency
Every 2 hours
Estimated price
$30 - $75
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$55 - $85
Business Coach Seat
$50 - $75
Room
$170 - $240
Train from Los Angeles Union Station Amtrak to San Jose Diridon Station Amtrak
Ave. Duration
10 h 1 min
Frequency
Once daily
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$290 - $400
Bus operators
AC Transit
Website
actransit.org
Bus from Union City BART to Middlefield Rd:Willow Rd
Ave. Duration
36 min
Frequency
Hourly
Estimated price
$3
Schedules at
actransit.org
Book at
actransit.org
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from San Diego, Ca to Los Angeles, Ca
Ave. Duration
2 h 25 min
Frequency
Hourly
Estimated price
$17 - $40
Website
greyhound.com
Economy
$17 - $27
Flexible
$30 - $40
Bus from Los Angeles, Ca to San Jose, Ca
Ave. Duration
6 h 45 min
Frequency
Hourly
Estimated price
$35 - $90
Website
greyhound.com
Economy
$35 - $60
Flexible
$70 - $90
Tufesa
Phone
016444102444
Website
tufesa.com.mx
Bus from San Diego, CA to Anaheim
Ave. Duration
2 h 39 min
Frequency
Twice daily
Estimated price
$9 - $21
Schedules at
tufesa.com.mx
Book at
gotobus.com
Plus
$9 - $14
Platinum
$15 - $19
Ejecutivo
$15 - $21
Bus from Anaheim to San Jose, CA
Ave. Duration
9 h 25 min
Frequency
Once daily
Estimated price
$24 - $65
Schedules at
tufesa.com.mx
Book at
gotobus.com
Plus
$24 - $35
Platinum
$35 - $45
Ejecutivo
$40 - $55

Want to know more about travelling around United States

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Questions & Answers

How far is it from San Diego to Palo Alto?

The distance between San Diego and Palo Alto is 694 km. The road distance is 767 km.

What is the cheapest way to get from San Diego to Palo Alto?

The cheapest way to get from San Diego to Palo Alto is to drive which costs $45 - $70 and takes 8 h 4 min.

What is the fastest way to get from San Diego to Palo Alto?

The quickest way to get from San Diego to Palo Alto is to fly and Caltrain which takes 3 h 38 min and costs $80 - $340.

Is there a direct train between San Diego and Palo Alto?

No, there is no direct train from San Diego to Palo Alto. However, there are services departing from San Diego Santa Fe Depot Amtrak and arriving at California Ave Caltrain via Los Angeles Union Station Amtrak and San Jose Diridon Caltrain. The journey, including transfers, takes approximately 14 h 47 min.

Is there a direct bus between San Diego and Palo Alto?

No, there is no direct bus from San Diego to Palo Alto. However, there are services departing from San Diego, CA and arriving at El Camino & California via Anaheim and King & Story. The journey, including transfers, takes approximately 14 h 53 min.

How long does it take to get from San Diego to Palo Alto?

It takes approximately 3 h 38 min to get from San Diego to Palo Alto, including transfers.