From San Diego Santa Fe Depot Amtrak train to Oceanside Transit Center then bus to Murr Hot Springs at 41200 Walmart. 3 h 11 min $34. From Broadway & 5th Av bus to Escondido Transit Center, bus to County Center Dr 41000 at Library, then line 23 bus to Hancock FS Rancho Spring Medical Ctr.. 3 h 54 min $11. From San Diego drive to Murrieta. 1 h 6 min $7.