There are 10 ways to get from San Antonio to South Carolina by plane, bus, night bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly San Antonio to Columbia  •  6 h 16 min

  1. Fly from San Antonio (SAT) to Columbia (CAE) SAT - CAE

$295 - $1,331

Cheapest option

Bus, Megabus  •  34 h 24 min

  1. Take the bus from San Antonio to DFW-Grand Prairie, Texas
  2. Take the Megabus from Grand Prairie to Marta Civic Center Station - Nb
  3. Take the bus from Atlanta, GA to Florence

$143 - $202

8 alternative options

Fly San Antonio to Greenville/Spartanburg  •  6 h 10 min

  1. Fly from San Antonio (SAT) to Greenville/Spartanburg (GSP) SAT - GSP

$201 - $796

Fly San Antonio to Charlotte  •  5 h 5 min

  1. Fly from San Antonio (SAT) to Charlotte (CLT) SAT - CLT

$256 - $741

Fly San Antonio to Charleston  •  7 h 11 min

  1. Fly from San Antonio (SAT) to Charleston (CHS) SAT - CHS

$283 - $1,304

Bus to Austin, fly to Charlotte  •  7 h 2 min

  1. Take the bus from San Antonio, Tx to Austin, Tx
  2. Fly from Austin (AUS) to Charlotte (CLT) AUS - CLT

$232 - $680

Bus  •  29 h 19 min

  1. Take the bus from San Antonio, Tx to Houston, Tx
  2. Take the bus from Houston, Tx to Atlanta, Ga
  3. Take the bus from Atlanta, Ga to Savannah, Ga
  4. Take the bus from Savannah, Ga to Florence, Sc

$150 - $382

Bus, night bus, train  •  30 h 12 min

  1. Take the bus from San Antonio, Tx to Houston, Tx
  2. Take the bus from Houston, Tx to Atlanta, Ga
  3. Take the night bus from Atlanta, Ga to Savannah, Ga
  4. Take the train from Savannah Amtrak to Florence Amtrak

$170 - $429

Train, bus  •  41 h 51 min

  1. Take the train from San Antonio Amtrak to New Orleans Union Passenger Terminal Amtrak
  2. Take the train from New Orleans Union Passenger Terminal Amtrak to Greensboro Galyon Transportation Center Amtrak
  3. Take the bus from Greensboro, Nc to Raleigh, Nc
  4. Take the bus from Raleigh, Nc to Florence, Sc

$229 - $657

Drive  •  20 h 40 min

  1. Drive from San Antonio to Florence 1278.7 miles

$120 - $190

Questions & Answers

The cheapest way to get from San Antonio to South Carolina is to drive which costs $120 - $190 and takes 20 h 40 min.

More details

The quickest way to get from San Antonio to South Carolina is to fly which costs $250 - $750 and takes 5 h 5 min.

More details

The distance between San Antonio and South Carolina is 1108 miles. The road distance is 1278.7 miles.

Get driving directions

It takes approximately 6 h 16 min to get from San Antonio to South Carolina, including transfers.

More details

No, there is no direct bus from San Antonio to South Carolina. However, there are services departing from San Antonio, Tx and arriving at Florence, Sc via Houston, Tx, Atlanta, Ga and Savannah, Ga. The journey, including transfers, takes approximately 29 h 19 min.

More details

What companies run services between San Antonio, TX, USA and South Carolina, USA?

Delta, United Airlines and American Airlines fly from San Antonio to Columbia hourly. Alternatively, you can take a bus from San Antonio to Florence via Houston, Tx, Atlanta, Ga, and Savannah, Ga in around 29 h 19 min.

Airlines
American Airlines
Website
aa.com
Flights from San Antonio to Columbia via Charlotte
Ave. Duration
5 h 48 min
When
Every day
Estimated price
$300 - $1,300
Flights from San Antonio to Columbia via Dallas/Ft.Worth
Ave. Duration
5 h 39 min
When
Every day
Estimated price
$300 - $1,300
Flights from San Antonio to Columbia via Philadelphia
Ave. Duration
8 h 37 min
When
Every day
Estimated price
$390 - $1,500
Flights from San Antonio to Greenville/Spartanburg via Dallas/Ft.Worth
Ave. Duration
4 h 39 min
When
Every day
Estimated price
$330 - $1,500
Flights from San Antonio to Greenville/Spartanburg via Charlotte
Ave. Duration
5 h 35 min
When
Every day
Estimated price
$330 - $1,500
Flights from San Antonio to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
5 h 45 min
When
Saturday
Estimated price
$330 - $1,500
Flights from San Antonio to Greenville/Spartanburg via Philadelphia
Ave. Duration
6 h 14 min
When
Every day
Estimated price
$330 - $1,500
Flights from San Antonio to Charlotte
Ave. Duration
2 h 58 min
When
Every day
Estimated price
$360 - $1,300
Flights from San Antonio to Charlotte via Dallas/Ft.Worth
Ave. Duration
4 h 51 min
When
Every day
Estimated price
$360 - $1,300
Flights from San Antonio to Charleston via Charlotte
Ave. Duration
5 h 42 min
When
Every day
Estimated price
$310 - $1,300
Flights from San Antonio to Charleston via Dallas/Ft.Worth
Ave. Duration
5 h 28 min
When
Every day
Estimated price
$310 - $1,300
Flights from Austin to Charlotte
Ave. Duration
2 h 53 min
When
Every day
Estimated price
$290 - $750
Flights from Austin to Charlotte via Dallas/Ft.Worth
Ave. Duration
4 h 40 min
When
Every day
Estimated price
$290 - $750
Delta
Website
delta.com
Flights from San Antonio to Columbia via Atlanta
Ave. Duration
5 h 24 min
When
Every day
Estimated price
$270 - $1,300
Flights from San Antonio to Greenville/Spartanburg via Atlanta
Ave. Duration
5 h 15 min
When
Every day
Estimated price
$330 - $1,500
Flights from San Antonio to Greenville/Spartanburg via Detroit
Ave. Duration
6 h 17 min
When
Saturday
Estimated price
$330 - $1,500
Flights from San Antonio to Charlotte via Atlanta
Ave. Duration
4 h 48 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$350 - $1,400
Flights from San Antonio to Charleston via Atlanta
Ave. Duration
5 h 4 min
When
Every day
Estimated price
$280 - $1,300
Flights from Austin to Charlotte via Atlanta
Ave. Duration
4 h 30 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$350 - $950
United Airlines
Website
united.com
Flights from San Antonio to Columbia via Houston
Ave. Duration
4 h 49 min
When
Every day
Estimated price
$300 - $1,400
Flights from San Antonio to Columbia via Washington Dulles
Ave. Duration
5 h 50 min
When
Every day
Estimated price
$370 - $1,600
Flights from San Antonio to Columbia via Chicago O'Hare
Ave. Duration
7 h 33 min
When
Every day
Estimated price
$360 - $1,600
Flights from San Antonio to Greenville/Spartanburg via Houston
Ave. Duration
5 h 10 min
When
Every day
Estimated price
$410 - $1,800
Flights from San Antonio to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
6 h 3 min
When
Every day
Estimated price
$410 - $1,800
Flights from San Antonio to Greenville/Spartanburg via Washington Dulles
Ave. Duration
6 h 10 min
When
Every day
Estimated price
$410 - $1,800
Flights from San Antonio to Charlotte via Houston
Ave. Duration
4 h 29 min
When
Every day
Estimated price
$370 - $1,500
Flights from San Antonio to Charleston via Houston
Ave. Duration
5 h 17 min
When
Every day
Estimated price
$310 - $1,400
Flights from San Antonio to Charleston via Chicago O'Hare
Ave. Duration
6 h 11 min
When
Monday to Friday
Estimated price
$370 - $1,600
Flights from San Antonio to Charleston via Washington Dulles
Ave. Duration
6 h 12 min
When
Every day
Estimated price
$370 - $1,600
Flights from Austin to Charlotte via Houston
Ave. Duration
4 h 36 min
When
Every day
Estimated price
$310 - $1,000
Southwest Airlines
Website
southwest.com
Flights from San Antonio to Greenville/Spartanburg via Atlanta
Ave. Duration
4 h 52 min
When
Every day
Estimated price
$270 - $1,100
Flights from San Antonio to Charlotte via Nashville
Ave. Duration
4 h 10 min
When
Saturday
Estimated price
$390 - $1,300
Flights from San Antonio to Charlotte via Houston Hobby Apt
Ave. Duration
4 h 10 min
When
Monday to Friday
Estimated price
$390 - $1,300
Flights from San Antonio to Charlotte via Dallas
Ave. Duration
4 h 47 min
When
Monday to Saturday
Estimated price
$390 - $1,300
Flights from San Antonio to Charleston via Houston Hobby Apt
Ave. Duration
4 h 57 min
When
Saturday and Sunday
Estimated price
$330 - $1,300
Flights from San Antonio to Charleston via St. Louis
Ave. Duration
4 h 57 min
When
Saturday and Sunday
Estimated price
$380 - $1,400
Flights from San Antonio to Charleston via Chicago Midway
Ave. Duration
5 h 45 min
When
Every day
Estimated price
$410 - $1,500
Flights from San Antonio to Charleston via Dallas
Ave. Duration
5 h 45 min
When
Saturday
Estimated price
$340 - $1,300
Flights from Austin to Charlotte via Nashville
Ave. Duration
4 h
When
Sunday
Estimated price
$370 - $1,200
Flights from Austin to Charlotte via Houston Hobby Apt
Ave. Duration
4 h 5 min
When
Monday to Friday
Estimated price
$370 - $1,200
Flights from Austin to Charlotte via Dallas
Ave. Duration
4 h 20 min
When
Monday to Friday
Estimated price
$370 - $1,200
Frontier Airlines
Website
flyfrontier.com
Flights from San Antonio to Charlotte
Ave. Duration
2 h 59 min
When
Tuesday, Thursday and Sunday
Estimated price
$140 - $600
Flights from Austin to Charlotte
Ave. Duration
2 h 45 min
When
Tuesday, Thursday and Sunday
Estimated price
$120 - $600
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Savannah Amtrak to Florence Amtrak
Ave. Duration
3 h 14 min
Frequency
Twice daily
Estimated price
$40 - $100
Website
amtrak.com
Coach Seat
$40 - $60
Flexi Coach Seat
$70 - $110
Business Coach Seat
$70 - $100
Room
$200 - $280
Train from San Antonio Amtrak to New Orleans Union Passenger Terminal Amtrak
Ave. Duration
15 h 15 min
Frequency
3 times a week
Estimated price
$85 - $240
Website
amtrak.com
Coach Seat
$85 - $130
Flexi Coach Seat
$150 - $220
Business Coach Seat
$160 - $240
Room
$350 - $490
Train from New Orleans Union Passenger Terminal Amtrak to Greensboro Galyon Transportation Center Amtrak
Ave. Duration
19 h 37 min
Frequency
Once daily
Estimated price
$110 - $340
Website
amtrak.com
Coach Seat
$110 - $180
Flexi Coach Seat
$210 - $300
Business Coach Seat
$240 - $340
Room
$470 - $650
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from San Antonio, Tx to Austin, Tx
Ave. Duration
1 h 30 min
Frequency
Every 30 minutes
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Bus from San Antonio, Tx to Houston, Tx
Ave. Duration
3 h 15 min
Frequency
Hourly
Estimated price
$24 - $60
Website
greyhound.com
Economy
$24 - $40
Flexible
$45 - $60
Bus from Houston, Tx to Atlanta, Ga
Ave. Duration
16 h 55 min
Frequency
Every 30 minutes
Estimated price
$75 - $200
Website
greyhound.com
Economy
$75 - $130
Flexible
$150 - $200
Bus from Atlanta, Ga to Savannah, Ga
Ave. Duration
4 h 35 min
Frequency
Every 30 minutes
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $70
Bus from Savannah, Ga to Florence, Sc
Ave. Duration
3 h 40 min
Frequency
Hourly
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Bus from Greensboro, Nc to Raleigh, Nc
Ave. Duration
1 h 45 min
Frequency
Hourly
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Bus from Raleigh, Nc to Florence, Sc
Ave. Duration
3 h 30 min
Frequency
Every 30 minutes
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from San Antonio to DFW-Grand Prairie, Texas
Ave. Duration
5 h 35 min
Frequency
4 times a day
Estimated price
$25 - $40
Schedules at
us.megabus.com
Bus from Grand Prairie to Marta Civic Center Station - Nb
Ave. Duration
18 h 10 min
Frequency
Once daily
Estimated price
$75 - $95
Schedules at
us.megabus.com

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