There are 10 ways to get from San Antonio to South Carolina by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly San Antonio to Greenville/Spartanburg  •  5 h 50 min

  1. Fly from San Antonio (SAT) to Greenville/Spartanburg (GSP) SAT - GSP

$201 - $796

Cheapest option

Bus via New Orleans  •  28 h

  1. Take the bus from San Antonio to New Orleans
  2. Take the bus from New Orleans to Marta Civic Center Station - Nb
  3. Take the bus from Atlanta GA to Columbia, SC
  4. Take the bus from Columbia, SC to Florence, SC

$128 - $190

8 alternative options

Fly San Antonio to Columbia  •  5 h 53 min

  1. Fly from San Antonio (SAT) to Columbia (CAE) SAT - CAE

$295 - $1,331

Fly San Antonio to Charlotte  •  5 h

  1. Fly from San Antonio (SAT) to Charlotte (CLT) SAT - CLT

$256 - $741

Fly San Antonio to Florence  •  7 h 11 min

  1. Fly from San Antonio (SAT) to Florence (FLO) SAT - FLO

$349 - $1,512

Fly San Antonio to Charleston  •  6 h 56 min

  1. Fly from San Antonio (SAT) to Charleston (CHS) SAT - CHS

$283 - $1,304

Bus to Austin, fly to Charlotte  •  6 h 53 min

  1. Take the bus from San Antonio, Tx to Austin, Tx
  2. Fly from Austin (AUS) to Charlotte (CLT) AUS - CLT

$232 - $680

Bus Greyhound USA  •  27 h 20 min

  1. Take the bus from San Antonio, Tx to Houston, Tx
  2. Take the bus from Houston, Tx to Atlanta, Ga
  3. Take the bus from Atlanta, GA to Florence, SC

$137 - $320

Train, bus  •  41 h 51 min

  1. Take the train from San Antonio Amtrak to New Orleans Union Passenger Terminal
  2. Take the train from New Orleans Union Passenger Terminal to Greensboro Galyon Transportation Center
  3. Take the bus from Greensboro, Nc to Raleigh, Nc
  4. Take the bus from Raleigh, Nc to Florence, Sc

$229 - $657

Drive  •  20 h 40 min

  1. Drive from San Antonio to Florence 1278.7 miles

$120 - $190

Questions & Answers

No, there is no direct bus from San Antonio to South Carolina. However, there are services departing from San Antonio, Tx and arriving at Florence, SC via Houston, Tx, Peachtree St @ Alabama St and Atlanta, GA. The journey, including transfers, takes approximately 27 h 20 min.

More details

The distance between San Antonio and South Carolina is 1108 miles. The road distance is 1278.7 miles.

Get driving directions

The best way to get from San Antonio to South Carolina without a car is to bus which takes 27 h 20 min and costs .

More details

It takes approximately 5 h 50 min to get from San Antonio to South Carolina, including transfers.

More details

San Antonio to South Carolina bus services, operated by Greyhound USA, depart from San Antonio, Tx station.

More details

The best way to get from San Antonio to South Carolina is to fly which takes 5 h 50 min and costs . Alternatively, you can bus, which costs and takes 27 h 20 min.

Mode details

There is no direct flight from San Antonio Airport to Greenville/Spartanburg Airport. The quickest flight takes 3 h 55 min and has one stopover.

Search flights

San Antonio to South Carolina bus services, operated by South Eastern Stages, arrive at Florence, SC station.

More details

South Carolina is 1 h ahead of San Antonio. It is currently 8:46 PM in San Antonio and 9:46 PM in South Carolina.

Yes, the driving distance between San Antonio to South Carolina is 1279 miles. It takes approximately 20 h 40 min to drive from San Antonio to South Carolina.

Get driving directions

Map of how to get from San Antonio to South Carolina.
Launch map view
  • Distance: 1108 miles
  • Duration: 5 h 50 min

What companies run services between San Antonio, TX, USA and South Carolina, USA?

Southwest Airlines, Delta and two other airlines fly from San Antonio to Greenville hourly. Alternatively, you can take a bus from San Antonio to Florence via Houston, Tx, Atlanta, Ga, Peachtree St @ Alabama St, Peachtree St Sw @ Brotherton Transportation Mall, and Atlanta, GA in around 27 h 20 min.

Airlines
American Airlines
Website
aa.com
Flights from San Antonio to Greenville/Spartanburg via Dallas/Ft.Worth
Ave. Duration
5 h 14 min
When
Every day
Estimated price
$330 - $1,500
Flights from San Antonio to Greenville/Spartanburg via Charlotte
Ave. Duration
5 h 55 min
When
Every day
Estimated price
$330 - $1,500
Flights from San Antonio to Greenville/Spartanburg via Philadelphia
Ave. Duration
6 h 13 min
When
Every day
Estimated price
$330 - $1,500
Flights from San Antonio to Columbia via Charlotte
Ave. Duration
5 h 32 min
When
Every day
Estimated price
$300 - $1,300
Flights from San Antonio to Columbia via Dallas/Ft.Worth
Ave. Duration
5 h 32 min
When
Every day
Estimated price
$300 - $1,300
Flights from San Antonio to Columbia via Philadelphia
Ave. Duration
8 h 42 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$390 - $1,500
Flights from San Antonio to Charlotte
Ave. Duration
2 h 52 min
When
Every day
Estimated price
$360 - $1,300
Flights from San Antonio to Charlotte via Dallas/Ft.Worth
Ave. Duration
4 h 38 min
When
Every day
Estimated price
$360 - $1,300
Flights from San Antonio to Florence via Charlotte
Ave. Duration
7 h 20 min
When
Every day
Estimated price
$340 - $1,500
Flights from San Antonio to Florence via Dallas/Ft.Worth, Charlotte
Ave. Duration
7 h 42 min
When
Every day
Estimated price
$350 - $1,500
Flights from San Antonio to Charleston via Dallas/Ft.Worth
Ave. Duration
4 h 38 min
When
Every day
Estimated price
$310 - $1,300
Flights from San Antonio to Charleston via Charlotte
Ave. Duration
5 h 17 min
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$310 - $1,300
Flights from Austin to Charlotte
Ave. Duration
2 h 46 min
When
Every day
Estimated price
$290 - $750
Flights from Austin to Charlotte via Dallas/Ft.Worth
Ave. Duration
4 h 37 min
When
Monday to Saturday
Estimated price
$290 - $750
Delta
Website
delta.com
Flights from San Antonio to Greenville/Spartanburg via Atlanta
Ave. Duration
4 h 47 min
When
Every day
Estimated price
$330 - $1,500
Flights from San Antonio to Greenville/Spartanburg via Detroit
Ave. Duration
5 h 51 min
When
Saturday
Estimated price
$330 - $1,500
Flights from San Antonio to Columbia via Atlanta
Ave. Duration
4 h 59 min
When
Every day
Estimated price
$270 - $1,300
Flights from San Antonio to Charlotte via Atlanta
Ave. Duration
4 h 30 min
When
Every day
Estimated price
$350 - $1,400
Flights from San Antonio to Charleston via Atlanta
Ave. Duration
4 h 57 min
When
Every day
Estimated price
$280 - $1,300
Flights from Austin to Charlotte via Atlanta
Ave. Duration
4 h 25 min
When
Every day
Estimated price
$350 - $950
Southwest Airlines
Website
southwest.com
Flights from San Antonio to Greenville/Spartanburg via Atlanta
Ave. Duration
4 h 55 min
When
Every day
Estimated price
$270 - $1,100
Flights from San Antonio to Charlotte via Nashville
Ave. Duration
4 h 20 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$390 - $1,300
Flights from San Antonio to Charlotte via Houston Hobby Apt
Ave. Duration
4 h 30 min
When
Saturday and Sunday
Estimated price
$390 - $1,300
Flights from San Antonio to Charleston via Nashville
Ave. Duration
4 h 25 min
When
Monday to Friday
Estimated price
$350 - $1,400
Flights from San Antonio to Charleston via Houston Hobby Apt
Ave. Duration
4 h 43 min
When
Every day
Estimated price
$330 - $1,300
Flights from San Antonio to Charleston via Dallas
Ave. Duration
5 h 35 min
When
Sunday
Estimated price
$340 - $1,300
Flights from San Antonio to Charleston via Chicago Midway
Ave. Duration
5 h 57 min
When
Every day
Estimated price
$410 - $1,500
Flights from Austin to Charlotte via Nashville
Ave. Duration
4 h 20 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$370 - $1,200
Flights from Austin to Charlotte via Houston Hobby Apt
Ave. Duration
4 h 30 min
When
Saturday
Estimated price
$370 - $1,200
United Airlines
Website
united.com
Flights from San Antonio to Greenville/Spartanburg via Houston
Ave. Duration
5 h 6 min
When
Every day
Estimated price
$410 - $1,800
Flights from San Antonio to Greenville/Spartanburg via Washington Dulles
Ave. Duration
6 h 2 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$410 - $1,800
Flights from San Antonio to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
5 h 55 min
When
Monday, Tuesday, Thursday, Friday, Saturday and Sunday
Estimated price
$410 - $1,800
Flights from San Antonio to Columbia via Houston
Ave. Duration
4 h 44 min
When
Every day
Estimated price
$300 - $1,400
Flights from San Antonio to Columbia via Washington Dulles
Ave. Duration
5 h 47 min
When
Every day
Estimated price
$370 - $1,600
Flights from San Antonio to Columbia via Chicago O'Hare
Ave. Duration
6 h 47 min
When
Every day
Estimated price
$360 - $1,600
Flights from San Antonio to Charlotte via Houston
Ave. Duration
4 h 34 min
When
Every day
Estimated price
$370 - $1,500
Flights from San Antonio to Charleston via Houston
Ave. Duration
4 h 46 min
When
Every day
Estimated price
$310 - $1,400
Flights from San Antonio to Charleston via Washington Dulles
Ave. Duration
5 h 39 min
When
Every day
Estimated price
$370 - $1,600
Flights from San Antonio to Charleston via Chicago O'Hare
Ave. Duration
5 h 59 min
When
Every day
Estimated price
$370 - $1,600
Flights from Austin to Charlotte via Houston
Ave. Duration
4 h 29 min
When
Monday to Saturday
Estimated price
$310 - $1,000
Frontier Airlines
Website
flyfrontier.com
Flights from Austin to Charlotte
Ave. Duration
2 h 43 min
When
Tuesday, Thursday and Sunday
Estimated price
$120 - $600
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from San Antonio Amtrak to New Orleans Union Passenger Terminal
Ave. Duration
15 h 15 min
Frequency
3 times a week
Estimated price
$85 - $240
Website
amtrak.com
Coach Seat
$85 - $130
Flexi Coach Seat
$150 - $220
Business Coach Seat
$160 - $240
Room
$350 - $490
Train from New Orleans Union Passenger Terminal to Greensboro Galyon Transportation Center
Ave. Duration
19 h 37 min
Frequency
Once daily
Estimated price
$110 - $340
Website
amtrak.com
Coach Seat
$110 - $180
Flexi Coach Seat
$210 - $300
Business Coach Seat
$240 - $340
Room
$470 - $650
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from San Antonio, Tx to Austin, Tx
Ave. Duration
1 h 30 min
Frequency
Every 15 minutes
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Bus from San Antonio, Tx to Houston, Tx
Ave. Duration
3 h 40 min
Frequency
Every 30 minutes
Estimated price
$24 - $60
Website
greyhound.com
Economy
$24 - $40
Flexible
$45 - $60
Bus from Houston, Tx to Atlanta, Ga
Ave. Duration
16 h 55 min
Frequency
Every 15 minutes
Estimated price
$75 - $200
Website
greyhound.com
Economy
$75 - $130
Flexible
$150 - $200
Bus from Greensboro, Nc to Raleigh, Nc
Ave. Duration
1 h 45 min
Frequency
Hourly
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Bus from Raleigh, Nc to Florence, Sc
Ave. Duration
3 h 30 min
Frequency
Every 30 minutes
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Atlanta, GA to Florence, SC
Ave. Duration
5 h 30 min
Frequency
Once daily
Estimated price
$35 - $60
Schedules at
southeasternstages.com
Bus from Columbia, SC to Florence, SC
Ave. Duration
1 h 20 min
Frequency
Once daily
Estimated price
$19 - $30
Schedules at
southeasternstages.com
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from San Antonio to New Orleans
Ave. Duration
10 h 40 min
Frequency
Twice daily
Estimated price
$45 - $65
Book at
megabus.com
Bus from New Orleans to Marta Civic Center Station - Nb
Ave. Duration
8 h 45 min
Frequency
Twice daily
Estimated price
$40 - $60
Book at
megabus.com
Bus from Atlanta GA to Columbia, SC
Ave. Duration
4 h 15 min
Frequency
Twice daily
Estimated price
$21 - $35
Book at
megabus.com

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More Questions & Answers

Southwest Airlines, United Airlines, American Airlines and Delta offer flights from San Antonio Airport to Greenville/Spartanburg Airport.

Search flights

There are 17+ hotels available in South Carolina. Prices start at $51 USD per night.

More details

The best way to get from San Antonio to San Antonio Airport is to line 5 bus which takes 38 min and costs .

More details