There are 7 ways to get from Saint Simons Island to Key West by plane, bus (Flixbus, Greyhound), taxi, train, bus, car, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Brunswick Golden Isles Airport
best- Fly from Brunswick Golden Isles Airport (BQK) to Key West International Airport (EYW)plane BQK - EYW
4h 55m$152–612Drive 579.4 mi
cheapest- Drive from Saint Simons Island to Key Westcar 579.4 mi
10h 28m$106–153Bus
- Take the bus from Brunswick to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
16h 35m$132–223Taxi, train, bus
- Take the taxi from Saint Simons Island to Jesup Stationtaxi
- Take the train from Jesup Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
19h 36m$191–350Bus to Jacksonville, fly
- Take the bus from Brunswick to Jacksonvillebus
- Fly from Jacksonville (JAX) to Key West International Airport (EYW)plane JAX - EYW
7h 45m$420–1,040Bus, ferry
- Take the bus from Brunswick to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry
17h 45m$243–318Bus, train
- Take the bus from Brunswick to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to West Palm Beach Bus Stationbus
- Take the train from West Palm Beach Station to Miami Airport Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
17h 52m$134–249
Brunswick Golden Isles Airport (BQK) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Saint Simons Island to Key West is to drive which costs $100 - $160 and takes 10h 28m.
The fastest way to get from Saint Simons Island to Key West is to fly which takes 4h 55m and costs $150 - $650.
The distance between Saint Simons Island and Key West is 483 miles. The road distance is 582.7 miles.
The best way to get from Saint Simons Island to Key West without a car is to bus which takes 16h 35m and costs $130 - $230.
It takes approximately 4h 55m to get from Saint Simons Island to Key West, including transfers.
The best way to get from Saint Simons Island to Key West is to fly which takes 4h 55m and costs $150 - $650. Alternatively, you can bus, which costs $130 - $230 and takes 16h 35m.
Yes, the driving distance between Saint Simons Island to Key West is 583 miles. It takes approximately 10h 28m to drive from Saint Simons Island to Key West.
There are 815+ hotels available in Key West.
What companies run services between Saint Simons Island, GA, USA and Key West, FL, USA?
Delta flies from Brunswick Golden Isles Airport (BQK) to Key West International Airport (EYW) twice daily. Alternatively, you can take a vehicle from Saint Simons Island to N Roosevelt & 3rd Street via Brunswick, Orlando Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 16h 35m.
- Website
- aa.com
Flights from Jacksonville to Key West International Airport via Miami
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $95–600
Flights from Jacksonville to Key West International Airport via Charlotte
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $150–800
- Website
- delta.com
Flights from Brunswick Golden Isles Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 21m
- When
- Every day
- Estimated price
- $100–550
Flights from Jacksonville to Key West International Airport via Atlanta
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $140–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jesup Station to Hollywood Amtrak Station
- Ave. Duration
- 10h 34m
- Frequency
- Once daily
- Estimated price
- $50–170
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $50–120
- Coach Seat short notice purchase
- $60–170
- Business - advance purchase
- $85–360
- Business Class
- $140–390
- Phone
- +1 800-874-7245
- Tri-RailCustomerExperience@sfrta.fl.gov
- Website
- tri-rail.com
Train from West Palm Beach Station to Miami Airport Station
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $5–11
- Website
- https://www.tri-rail.com
- Weekend | Holiday
- $5
- Weekday
- $8–11
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Brunswick to Orlando Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- 6 times a week
- Estimated price
- $35–70
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 4h 50m
- Frequency
- Hourly
- Estimated price
- $28–60
- Schedules at
- flixbus.com
Bus from Brunswick to Jacksonville
- Ave. Duration
- 1h
- Frequency
- 6 times a week
- Estimated price
- $14–20
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 4h 55m
- Frequency
- 4 times a day
- Estimated price
- $30–55
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to West Palm Beach Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $27–75
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $28–55
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- https://www.greyhound.com/
Bus from Brunswick to Jacksonville
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $13–18
- Website
- https://www.greyhound.com/
Bus from Orlando Bus Station to West Palm Beach Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- Twice daily
- Estimated price
- $25–55
- Website
- https://www.greyhound.com/
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
- Ave. Duration
- 1h 3m
- Estimated price
- $110–140
On Time Taxi
- Phone
- +1 912-506-2683
- Website
- ontimetaxijamaica.com
Metro Cab
- Phone
- +1 912-554-2000
- Website
- metrocabbrunswick.com
Latino Taxi
- Phone
- +1 912-289-4732
- Website
- latinotaxi.com
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