There are 9 ways to get from Saint Simons Island to Florida Keys by plane, bus (Flixbus, Greyhound), taxi, train, bus, car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Brunswick Golden Isles Airport to Key West International Airport
best- Fly from Brunswick Golden Isles Airport (BQK) to Key West International Airport (EYW)plane BQK - EYW
7h 31m$218–693Drive 563.9 mi
cheapest- Drive from Saint Simons Island to Florida Keyscar 563.9 mi
10h 5m$103–149Bus
- Take the bus from Brunswick to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
15h 48m$126–207Taxi, train, bus
- Take the taxi from Saint Simons Island to Jesup Stationtaxi
- Take the train from Jesup Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
18h 49m$190–344Drive to Savannah, fly to Key West International Airport
- Drive from Saint Simons Island to Savannah-Airport-SAVcar
- Fly from Savannah (SAV) to Key West International Airport (EYW)plane SAV - EYW
7h 44m$262–615Drive to Savannah, fly to Miami International Airport, shuttle
- Drive from Saint Simons Island to Savannah-Airport-SAVcar
- Fly from Savannah (SAV) to Miami International Airport (MIA)plane SAV - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
8h 32m$307–655Bus to Jacksonville, fly to Key West International Airport
- Take the bus from Brunswick to Jacksonvillebus
- Fly from Jacksonville (JAX) to Key West International Airport (EYW)plane JAX - EYW
10h 26m$362–1,236Bus, train
- Take the bus from Brunswick to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to West Palm Beach Bus Stationbus
- Take the train from West Palm Beach Station to Miami Airport Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
17h 5m$128–218Bus, shuttle
- Take the bus from Brunswick to Orlando Bus Stationbus
- Take the bus from Orlando - RedCoach Station, FL to Miami Airportbus
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
17h 14m$253–450
Brunswick Golden Isles Airport (BQK) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Saint Simons Island to Florida Keys is to drive which costs $100 - $150 and takes 10h 5m.
The fastest way to get from Saint Simons Island to Florida Keys is to fly which takes 7h 31m and costs $210 - $700.
The distance between Saint Simons Island and Florida Keys is 502 miles. The road distance is 567.2 miles.
The best way to get from Saint Simons Island to Florida Keys without a car is to bus which takes 15h 48m and costs $120 - $210.
It takes approximately 7h 31m to get from Saint Simons Island to Florida Keys, including transfers.
The best way to get from Saint Simons Island to Florida Keys is to fly which takes 7h 31m and costs $210 - $700. Alternatively, you can bus, which costs $120 - $210 and takes 15h 48m.
Yes, the driving distance between Saint Simons Island to Florida Keys is 567 miles. It takes approximately 10h 5m to drive from Saint Simons Island to Florida Keys.
There are 943+ hotels available in Florida Keys.
What companies run services between Saint Simons Island, GA, USA and Florida Keys, FL, USA?
Delta flies from Brunswick Golden Isles Airport (BQK) to Key West International Airport (EYW) 4 times a day. Alternatively, you can take a vehicle from Saint Simons Island to Florida Keys via Brunswick, Orlando Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 15h 48m.
- Website
- delta.com
Flights from Brunswick Golden Isles Airport to Key West International Airport via Atlanta
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- $100–550
Flights from Savannah to Key West International Airport via Atlanta
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $130–700
Flights from Jacksonville to Key West International Airport via Atlanta
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $150–800
- Website
- aa.com
Flights from Savannah to Key West International Airport via Charlotte
- Ave. Duration
- 6h 34m
- When
- Every day
- Estimated price
- $130–700
Flights from Savannah to Key West International Airport via Miami International Airport
- Ave. Duration
- 7h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
Flights from Savannah to Miami International Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $65–400
Flights from Jacksonville to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 32m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–650
Flights from Jacksonville to Key West International Airport via Charlotte
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $160–850
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jesup Station to Hollywood Amtrak Station
- Ave. Duration
- 10h 34m
- Frequency
- Once daily
- Estimated price
- $50–170
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $50–120
- Coach Seat short notice purchase
- $60–170
- Business - advance purchase
- $85–360
- Business Class
- $140–390
- Phone
- +1 800-874-7245
- Tri-RailCustomerExperience@sfrta.fl.gov
- Website
- tri-rail.com
Train from West Palm Beach Station to Miami Airport Station
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $5–11
- Website
- https://www.tri-rail.com
- Weekend | Holiday
- $5
- Weekday
- $8–11
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Brunswick to Orlando Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- 6 times a week
- Estimated price
- $30–70
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 4h 50m
- Frequency
- Hourly
- Estimated price
- $28–50
- Schedules at
- flixbus.com
Bus from Brunswick to Jacksonville
- Ave. Duration
- 1h
- Frequency
- 6 times a week
- Estimated price
- $9–85
- Schedules at
- flixbus.com
- Adult
- $9–85
Bus from Orlando Bus Station to West Palm Beach Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $27–50
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $28–50
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $21–29
- Website
- https://www.greyhound.com/
Bus from Brunswick to Jacksonville
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $13–16
- Website
- https://www.greyhound.com/
Bus from Orlando Bus Station to West Palm Beach Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- Twice daily
- Estimated price
- $25–40
- Website
- https://www.greyhound.com/
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- https://www.keysshuttle.com
Shuttle from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- https://www.keysshuttle.com
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Orlando - RedCoach Station, FL to Miami Airport
- Ave. Duration
- 4h 45m
- Frequency
- Every 4 hours
- Estimated price
- $24–140
- Website
- https://www.redcoachusa.com
- Web
- $24–140
- Ave. Duration
- 1h 3m
- Estimated price
- $110–140
On Time Taxi
- Phone
- +1 912-506-2683
- Website
- ontimetaxijamaica.com
Metro Cab
- Phone
- +1 912-554-2000
- Website
- metrocabbrunswick.com
Latino Taxi
- Phone
- +1 912-289-4732
- Website
- latinotaxi.com
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