There are 5 ways to get from Saint Paul to St. Louis by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  3 h 29 min

  1. MSP - STL

$124 - $354

Cheapest option

Bus Megabus  •  14 h 45 min

  1. via Chicago

$58 - $93

3 alternative options

Bus Jefferson Lines  •  14 h 13 min

  1. 801 / ...
  2. 1682 / ...

$111 - $193

Train  •  14 h 25 min

  1. Empire Builder
  2. Lincoln Service / ...

$116 - $303

Drive  •  9 h 43 min

  1. 531.2 miles

$50 - $75

What companies run services between Saint Paul, MN, USA and St. Louis, MO, USA?

Southwest Airlines, Delta and two other airlines fly from Saint Paul to St. Louis hourly. Alternatively, you can take a bus from Saint Paul to St. Louis via 7th St N & Hennepin Ave / 1st Ave, Minneapolis, MN, Kansas City, MO, and Kansas City, Mo in around 14 h 13 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Minneapolis to St. Louis
Ave. Duration
1 h 26 min
When
Every day
Estimated price
$200 - $900
Delta
Website
delta.com
Flights from Minneapolis to St. Louis
Ave. Duration
1 h 32 min
When
Every day
Estimated price
$270 - $750
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from St. Paul-Minneapolis Union Depot Amtrak to Chicago Union Station Amtrak
Ave. Duration
7 h 55 min
Frequency
3 times a day
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$280 - $400
Train from Chicago Union Station Amtrak to St. Louis Gateway Station Amtrak
Ave. Duration
5 h 30 min
Frequency
Every 4 hours
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Jefferson Lines
Phone
800-451-5333
Email
info@jeffersonlines.com
Website
jeffersonlines.com
Bus from Minneapolis, MN to Kansas City, MO
Ave. Duration
8 h 45 min
Frequency
Hourly
Estimated price
$80 - $120
Schedules at
jeffersonlines.com
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Kansas City, Mo to St Louis, Mo
Ave. Duration
4 h
Frequency
Hourly
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from St Paul, MN to Chicago
Ave. Duration
8 h
Frequency
4 times a day
Estimated price
$29 - $55
Schedules at
us.megabus.com
Bus from Chicago to St. Louis
Ave. Duration
5 h 45 min
Frequency
4 times a day
Estimated price
$29 - $40
Schedules at
us.megabus.com

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Questions & Answers

The distance between Saint Paul and St. Louis is 742 km. The road distance is 850 km.

The cheapest way to get from Saint Paul to St. Louis is to drive which costs $50 - $75 and takes 9 h 43 min.

The quickest way to get from Saint Paul to St. Louis is to fly which takes 3 h 29 min and costs $120 - $360.

No, there is no direct train from Saint Paul to St. Louis. However, there are services departing from St. Paul-Minneapolis Union Depot Amtrak and arriving at St. Louis Gateway Station Amtrak via Chicago Union Station Amtrak. The journey, including transfers, takes approximately 14 h 25 min.

No, there is no direct bus from Saint Paul to St. Louis. However, there are services departing from 6th St & Cedar St and arriving at St Louis, Mo via Minneapolis, MN and Kansas City, Mo. The journey, including transfers, takes approximately 14 h 13 min.

It takes approximately 3 h 29 min to get from Saint Paul to St. Louis, including transfers.