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There are 5 ways to get from Saint Paul to St. Louis by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  3h 42m

  1. Fly from Minneapolis (MSP) to St. Louis (STL) MSP - STL

$125 - $356

Cheapest option

Bus Megabus  •  15h 10m

  1. Take the bus from St Paul, MN to Chicago
  2. Take the bus from Chicago, IL to St. Louis via St Louis

$66 - $93

3 alternative options

Train  •  14h 25m

  1. Take the train from St. Paul-Minneapolis Union Depot to Chicago Union Station Empire Builder
  2. Take the train from Chicago Union Station to St. Louis Gateway Station Lincoln Service / ...

$116 - $303

Bus Jefferson Lines  •  15h 9m

  1. Take the bus from Minneapolis, MN to Kansas City, MO 801 / ...
  2. Take the bus from Kansas City, Mo to St Louis, Mo 1682 / ...

$111 - $193

Drive  •  9h 43m

  1. Drive from Saint Paul to St. Louis 531.2 miles

$50 - $75

Questions & Answers

The cheapest way to get from Saint Paul to St. Louis is to drive which costs $50 - $75 and takes 9h 43m.

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The quickest way to get from Saint Paul to St. Louis is to fly which costs $120 - $360 and takes 3h 42m.

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No, there is no direct bus from Saint Paul to St. Louis. However, there are services departing from 6th St & Cedar St and arriving at St Louis, Mo via Minneapolis, MN and Kansas City, Mo. The journey, including transfers, takes approximately 15h 9m.

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No, there is no direct train from Saint Paul to St. Louis station. However, there are services departing from St. Paul-Minneapolis Union Depot and arriving at St. Louis Gateway Station via Chicago Union Station. The journey, including transfers, takes approximately 14h 25m.

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The distance between Saint Paul and St. Louis is 464 miles. The road distance is 531.2 miles.

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The best way to get from Saint Paul to St. Louis without a car is to train which takes 14h 25m and costs $110 - $310.

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It takes approximately 3h 42m to get from Saint Paul to St. Louis, including transfers.

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Saint Paul to St. Louis bus services, operated by Jefferson Lines, depart from Minneapolis, MN station.

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Saint Paul to St. Louis train services, operated by Amtrak, depart from St. Paul-Minneapolis Union Depot station.

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The best way to get from Saint Paul to St. Louis is to fly which takes 3h 42m and costs $120 - $360. Alternatively, you can train, which costs $110 - $310 and takes 14h 25m, you could also bus, which costs $110 - $200 and takes 15h 9m.

Mode details

Map of how to get from Saint Paul to St. Louis.
Launch map view
  • Distance: 463.9 miles
  • Duration: 3h 42m

What companies run services between Saint Paul, MN, USA and St. Louis, MO, USA?

Southwest Airlines, Delta and United Airlines fly from Saint Paul to St. Louis every 3 hours. Alternatively, you can take a train from Saint Paul to St. Louis via Chicago Union Station in around 14h 25m.

Airlines
Delta
Website
delta.com
Flights from Minneapolis to St. Louis
Ave. Duration
1h 43m
When
Every day
Estimated price
$270 - $750
Southwest Airlines
Website
southwest.com
Flights from Minneapolis to St. Louis
Ave. Duration
1h 29m
When
Every day
Estimated price
$200 - $900
Flights from Minneapolis to St. Louis via Chicago Midway
Ave. Duration
3h 37m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $900
United Airlines
Website
united.com
Flights from Minneapolis to St. Louis via Chicago O'Hare
Ave. Duration
3h 49m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$290 - $900
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from St. Paul-Minneapolis Union Depot to Chicago Union Station
Ave. Duration
7h 55m
Frequency
3 times a day
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$280 - $400
Train from Chicago Union Station to St. Louis Gateway Station
Ave. Duration
5h 30m
Frequency
Every 4 hours
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Jefferson Lines
Phone
800-451-5333
Email
info@jeffersonlines.com
Website
jeffersonlines.com
Bus from Minneapolis, MN to Kansas City, MO
Ave. Duration
8h 45m
Frequency
Twice daily
Estimated price
$80 - $120
Book at
jeffersonlines.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Kansas City, Mo to St Louis, Mo
Ave. Duration
4h
Frequency
3 times a day
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from St Paul, MN to Chicago
Ave. Duration
8h 10m
Frequency
4 times a day
Estimated price
$35 - $55
Book at
megabus.com
Bus from Chicago, IL to St. Louis
Ave. Duration
6h
Frequency
Twice daily
Estimated price
$29 - $40
Book at
megabus.com

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Minneapolis Airport to St. Louis Airport is the direct flight which takes 1h 25m.

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Saint Paul to St. Louis bus services, operated by Greyhound USA, arrive at St Louis, Mo station.

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Saint Paul to St. Louis train services, operated by Amtrak, arrive at St. Louis Gateway Station.

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Yes, the driving distance between Saint Paul to St. Louis is 531 miles. It takes approximately 9h 43m to drive from Saint Paul to St. Louis.

Get driving directions

United Airlines, Southwest Airlines and Delta offer flights from Minneapolis Airport to St. Louis Airport.

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Book your Saint Paul to St. Louis train tickets online with Rome2rio.

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There are 200+ hotels available in St. Louis. Prices start at $65 USD per night.

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The best way to get from Saint Paul to Minneapolis Airport is to line 54 bus which takes 24m and costs $2 - $3.

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