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How to get fromSaint Charles to Iowaby bus, plane, bus (Greyhound), train or car

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There are 5 ways to get from Saint Charles to Iowa by bus, plane, bus (Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 34 bus, fly to Des Moines

    best
    1. Take the bus from 4375 Rider Trail North Sb to North Hanley Transit Centerbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM)plane plane STL - DSM
    3h 4m
    $86–485
  2. Drive 311.3 mi

    cheapest
    1. Drive from Saint Charles to Des Moinescar car 311.3 mi
    6h 15m
    $57–83
  3. Bus

    1. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus Greyhound US1200 / ...
    2. Take the bus from Kansas City to Des Moinesbus bus Jefferson 802 / ...
    10h 35m
    $65–180
  4. Train, bus

    1. Take the train from St. Louis to Kansas Citytrain train Missouri River Runner / ...
    2. Take the bus from Kansas City to Des Moinesbus bus Jefferson 802 / ...
    12h 21m
    $60–295
  5. Fly to Omaha

    1. Fly from Lambert–St. Louis International Airport (STL) to Omaha (OMA)plane plane STL - OMA
    3h 18m
    $209–1,334

Lambert–St. Louis International Airport (STL) to Des Moines (DSM) flights

Calendar14Weekly Planes
Duration1h 10mAverage Duration
Ticket$66Cheapest Price
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Questions & Answers

What companies run services between Saint Charles, MO, USA and Iowa, USA?

You can take a bus from 4375 Rider Trail North Sb to Des Moines via North Hanley Transit Center, NORTH HANLEY station, CIVIC CENTER station, St Louis Bus Station, Kansas City, and Des Moines in around 10h 35m. Alternatively, Southwest Airlines flies from Lambert–St. Louis International Airport (STL) to Omaha (OMA) twice daily.

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