There are 6 ways to get from Saint Charles to Appleton by plane, train, bus, bus (Flixbus, Greyhound), car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Appleton International Airport
best- Fly from Lambert–St. Louis International Airport (STL) to Appleton International Airport (ATW)plane STL - ATW
5h 45m$91–428Drive 456.4 mi
cheapest- Drive from Saint Charles to Appletoncar 456.4 mi
7h 53m$84–121Train, bus
- Take the train from St. Louis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Milwaukeetrain
- Take the bus from Milwaukee to Oshkoshbus
12h 25m$277–417Bus
- Take the bus from St Louis Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus
- Take the bus from Milwaukee to Oshkoshbus
14h 31m$138–200Fly to Green Bay, taxi
- Fly from Lambert–St. Louis International Airport (STL) to Green Bay (GRB)plane STL - GRB
- Take the taxi from Green Bay (GRB) to Appletontaxi
6h 14m$177–530Fly to General Mitchell International Airport, bus
- Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)plane STL - MKE
- Take the bus from Milwaukee to Oshkoshbus
6h 41m$563–954
Lambert–St. Louis International Airport (STL) to Appleton International Airport (ATW) flights
Comparing Your Travel Options
The cheapest way to get from Saint Charles to Appleton is to drive which costs $80 - $120 and takes 7h 53m.
The fastest way to get from Saint Charles to Appleton is to fly which takes 5h 45m and costs $90 - $430.
No, there is no direct bus from Saint Charles to Appleton. However, there are services departing from 4375 Rider Trail North Sb and arriving at Oshkosh via North Hanley Transit Center, St Louis Bus Station, Chicago Bus Station and Milwaukee. The journey, including transfers, takes approximately 14h 31m.
The distance between Saint Charles and Appleton is 422 miles. The road distance is 459 miles.
The best way to get from Saint Charles to Appleton without a car is to train and bus which takes 12h 25m and costs $270 - $420.
It takes approximately 5h 45m to get from Saint Charles to Appleton, including transfers.
Saint Charles to Appleton bus services, operated by Flixbus USA, depart from St Louis Bus Station.
The best way to get from Saint Charles to Appleton is to fly which takes 5h 45m and costs $90 - $430. Alternatively, you can bus, which costs $130 - $200 and takes 14h 31m.
Saint Charles to Appleton bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
Yes, the driving distance between Saint Charles to Appleton is 459 miles. It takes approximately 7h 53m to drive from Saint Charles to Appleton.
What companies run services between Saint Charles, MO, USA and Appleton, WI, USA?
United Airlines, Delta, and American Airlines fly from Lambert–St. Louis International Airport (STL) to Appleton International Airport (ATW) hourly. Alternatively, you can take a vehicle from Saint Charles to Appleton via 4375 Rider Trail North Sb, North Hanley Transit Center, Civic Center Transit Center, St Louis Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Oshkosh in around 14h 31m.
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Appleton International Airport via Minneapolis
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $80–450
Flights from Lambert–St. Louis International Airport to Appleton International Airport via Detroit
- Ave. Duration
- 6h 31m
- When
- Every day
- Estimated price
- $85–460
Flights from Lambert–St. Louis International Airport to Appleton International Airport via Atlanta
- Ave. Duration
- 7h 43m
- When
- Every day
- Estimated price
- $120–600
Flights from Lambert–St. Louis International Airport to Green Bay via Minneapolis
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $80–450
Flights from Lambert–St. Louis International Airport to Green Bay via Atlanta
- Ave. Duration
- 6h 13m
- When
- Every day
- Estimated price
- $120–600
Flights from Lambert–St. Louis International Airport to Green Bay via Detroit
- Ave. Duration
- 6h 34m
- When
- Every day
- Estimated price
- $85–460
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $60–390
Flights from Lambert–St. Louis International Airport to Green Bay via Chicago O'Hare
- Ave. Duration
- 4h 6m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $65–390
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $60–390
Flights from Lambert–St. Louis International Airport to Appleton International Airport via Charlotte
- Ave. Duration
- 7h 9m
- When
- Every day
- Estimated price
- $120–600
Flights from Lambert–St. Louis International Airport to Appleton International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 19m
- When
- Wednesday
- Estimated price
- $130–650
Flights from Lambert–St. Louis International Airport to Green Bay via Chicago O'Hare
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $65–390
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to General Mitchell International Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- $80–550
Flights from Lambert–St. Louis International Airport to General Mitchell International Airport via Chicago Midway
- Ave. Duration
- 3h 25m
- When
- Saturday
- Estimated price
- $80–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $150–240
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
- Phone
- 920 496 3600
- Website
- example.com
Bus from Milwaukee to Oshkosh
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $20–23
- Schedules at
- golamers.com
Bus from Milwaukee to Oshkosh
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $20–23
- Schedules at
- golamers.com
Bus from Milwaukee to Oshkosh
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $21–24
- Schedules at
- golamers.com
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- $45–75
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $13–21
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $15–24
- Website
- Greyhound
- Ave. Duration
- 41 min
- Estimated price
- $95–120
Yellow Cab Green Bay
- Phone
- +1-920-435-1111
- Website
- yellowcabgreenbay.com
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Booking & Getting There
There are 58+ hotels available in Appleton.










