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How to get fromSaint Charles to Appletonby plane, train, bus, bus (Flixbus) or car

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There are 6 ways to get from Saint Charles to Appleton by plane, train, bus, bus (Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Appleton International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Appleton International Airport (ATW)plane plane STL - ATW
    5h 21m
    $98–527

  2. Bus (Flixbus)

    cheapest
    1. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus N2521 / ...
    2. Take the bus from Chicago Bus Station to Appleton Transit Centerbus bus FlixBus 2550
    13h 45m
    $69–109

  3. Train, bus

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Milwaukeetrain train
    3. Take the bus from Milwaukee to Appleton Amtrak Stationbus bus
    12h 36m
    $86–181

  4. Drive 456.4 mi

    1. Drive from Saint Charles to Appletoncar car 456.4 mi
    7h 53m
    $84–121

  5. Fly to Green Bay

    1. Fly from Lambert–St. Louis International Airport (STL) to Green Bay (GRB)plane plane STL - GRB
    6h 57m
    $119–547

  6. Fly to General Mitchell International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)plane plane STL - MKE
    2. Take the bus from Milwaukee Airport Amtrak Bus Stop to Appleton Amtrak Stationbus bus
    6h 51m
    $166–1,032

Saint Charles to Appleton by bus and train

Calendar26Weekly Services
Duration12h 36mAverage Duration
Ticket$86Cheapest Price
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Questions & Answers

What companies run services between Saint Charles, MO, USA and Appleton, WI, USA?

American Airlines, United Airlines, and Delta fly from Lambert–St. Louis International Airport (STL) to Appleton International Airport (ATW) hourly. Alternatively, you can take a bus from 4375 Rider Trail North Sb to Appleton Transit Center via North Hanley Transit Center, NORTH HANLEY station, CIVIC CENTER station, St Louis Bus Station, and Chicago Bus Station in around 13h 45m.

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