There are 7 ways to get from Saco to Pittsburgh by train, plane, bus, train (Amtrak), bus (Flixbus, Greyhound), car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Portland, fly, bus
best- Take the train from Saco Amtrak Station to Portlandtrain
- Fly from Portland (PWM) to Pittsburgh International Airport (PIT)plane PWM - PIT
- Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus
6h 4mBus via Boston
cheapest- Take the bus from Dyer Library to St John Stbus 60
- Take the bus from City of Portland to Bostonbus
- Take the bus from Boston to New Yorkbus
- Take the bus from Port Authority Bus Terminal to Pittsburgh Greyhoundbus
18h 27m$107–222Train (Amtrak)
- Take the train from Saco Amtrak Station to Bostontrain
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Pittsburgh Amtrak Stationtrain
17h 14m$213–1,096Drive 652.3 mi
- Drive from Saco to Pittsburghcar 652.3 mi
11h 48m$119–172Train to Boston Logan Airport, fly
- Take the train from Saco Amtrak Station to Woburn Amtrak Stationtrain
- Fly from Boston Logan Airport (BOS) to Pittsburgh International Airport (PIT)plane BOS - PIT
7h 2m$445–1,014Train, train to Theodore Francis Green State Airport, fly
- Take the train from Saco Amtrak Station to Bostontrain
- Take the train from Ruggles to TF Green Airporttrain
- Fly from Theodore Francis Green State Airport (PVD) to Pittsburgh International Airport (PIT)plane PVD - PIT
9h 2m$172–781Bus
- Take the bus from Dyer Library to St John Stbus 60
- Take the bus from City of Portland to New York Midtownbus
- Take the bus from New York Midtown to Pittsburgh Intermodal Stationbus
19h 5m$112–192
Saco to Pittsburgh by train and subway (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Saco to Pittsburgh is to bus via Boston which costs $100 - $230 and takes 18h 27m.
The fastest way to get from Saco to Pittsburgh is to train and fly which takes 7h 2m and costs $440 - $1,100.
No, there is no direct bus from Saco to Pittsburgh. However, there are services departing from Dyer Library and arriving at Pittsburgh Greyhound via City of Portland, Boston and Port Authority Bus Terminal. The journey, including transfers, takes approximately 18h 27m.
No, there is no direct train from Saco station to Pittsburgh station. However, there are services departing from Saco Amtrak Station and arriving at Pittsburgh Amtrak Station via North Station, Boston and Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 17h 14m.
The distance between Saco and Pittsburgh is 605 miles. The road distance is 656.1 miles.
The best way to get from Saco to Pittsburgh without a car is to train which takes 17h 14m and costs $210 - $1,100.
It takes approximately 6h 4m to get from Saco to Pittsburgh, including transfers.
Saco to Pittsburgh bus services, operated by Biddeford Saco Old Orchard Beach Transit, depart from Dyer Library station.
Saco to Pittsburgh train services, operated by Amtrak, depart from Saco Amtrak Station.
The best way to get from Saco to Pittsburgh is to train which takes 17h 14m and costs $210 - $1,100. Alternatively, you can bus via Boston, which costs $100 - $230 and takes 18h 27m.
What companies run services between Saco, ME, USA and Pittsburgh, PA, USA?
You can take a train from Saco Amtrak Station to Pittsburgh Amtrak Station via Boston, North Station, Back Bay, Boston, and Ny Moynihan Train Hall At Penn Station in around 17h 14m. Alternatively, you can take a bus from Dyer Library to Pittsburgh Greyhound via St John St, City of Portland, Boston, New York, and Port Authority Bus Terminal in around 18h 27m.
- Website
- united.com
Flights from Portland to Pittsburgh International Airport via Washington Dulles
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $100–600
Flights from Portland to Pittsburgh International Airport via Newark
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $95–550
Flights from Boston Logan Airport to Pittsburgh International Airport via Washington Dulles
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $80–440
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport via Washington Dulles
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $70–400
- Website
- southwest.com
Flights from Portland to Pittsburgh International Airport via Baltimore
- Ave. Duration
- 4h 37m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $100–550
Flights from Boston Logan Airport to Pittsburgh International Airport via Baltimore
- Ave. Duration
- 3h 53m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $75–440
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport via Baltimore
- Ave. Duration
- 3h 46m
- When
- Monday to Wednesday
- Estimated price
- $70–400
- Website
- aa.com
Flights from Portland to Pittsburgh International Airport via Philadelphia
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $100–550
Flights from Boston Logan Airport to Pittsburgh International Airport via Philadelphia
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $75–430
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport via Philadelphia
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $65–390
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport via Reagan Washington
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $70–400
- Website
- delta.com
Flights from Portland to Pittsburgh International Airport via New York La Guardia
- Ave. Duration
- 4h 12m
- When
- Sunday
- Estimated price
- $95–550
Flights from Boston Logan Airport to Pittsburgh International Airport
- Ave. Duration
- 2h 3m
- When
- Every day
- Estimated price
- $70–420
- Website
- jetblue.com
Flights from Boston Logan Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $70–420
- Website
- flybreeze.com
Flights from Portland to Pittsburgh International Airport
- Ave. Duration
- 1h 53m
- When
- Thursday, Sunday, and Tuesday
- Estimated price
- $260–1,100
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 40m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $130–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Saco Amtrak Station to Portland
- Ave. Duration
- 25 min
- Frequency
- 5 times a day
- Estimated price
- $4–10
- Website
- Amtrak
Train from Saco Amtrak Station to Boston
- Ave. Duration
- 2h 10m
- Frequency
- Every 4 hours
- Estimated price
- $29–65
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 57m
- Frequency
- Every 3 hours
- Estimated price
- $65–150
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Pittsburgh Amtrak Station
- Ave. Duration
- 9h 13m
- Frequency
- Once daily
- Estimated price
- $130–280
- Website
- Amtrak
Train from Saco Amtrak Station to Woburn Amtrak Station
- Ave. Duration
- 1h 49m
- Frequency
- Every 4 hours
- Estimated price
- $25–55
- Website
- Amtrak
Train from Saco Amtrak Station to Boston
- Ave. Duration
- 2h 10m
- Frequency
- Every 4 hours
- Estimated price
- $29–65
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 44m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Train from Ruggles to TF Green Airport
- Ave. Duration
- 1h 17m
- Frequency
- Every 4 hours
- Estimated price
- $9–15
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–15
- Phone
- +1 412-442-2000
- Website
- Pittsburgh Regional Transit
Bus from Pittsburgh International Airport to Seventh Ave + William Penn Pl
- Ave. Duration
- 41 min
- Frequency
- Every 30 minutes
- Website
- Pittsburgh Regional Transit
- Phone
- 207 282 5408
- Website
- BSOOB
Bus from Dyer Library to St John St
- Ave. Duration
- 1h 9m
- Frequency
- Every 4 hours
- Estimated price
- $2
- Website
- BSOOB
Bus from Dyer Library to St John St
- Ave. Duration
- 1h 9m
- Frequency
- Every 4 hours
- Estimated price
- $2
- Website
- BSOOB
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from City of Portland to Boston
- Ave. Duration
- 2h 1m
- Frequency
- Once daily
- Estimated price
- $15–26
- Schedules at
- Flixbus USA
Bus from City of Portland to New York Midtown
- Ave. Duration
- 7h 16m
- Frequency
- Once daily
- Estimated price
- $45–80
- Schedules at
- Flixbus USA
Bus from New York Midtown to Pittsburgh Intermodal Station
- Ave. Duration
- 8h 40m
- Frequency
- 3 times a day
- Estimated price
- $65–110
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from City of Portland to Boston
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $15–30
- Website
- Greyhound
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from Boston to New York
- Ave. Duration
- 4h 35m
- Frequency
- Hourly
- Estimated price
- $40–110
- Website
- Peter Pan
- Phone
- +1-877-462-6342
- questions@us.megabus.com
- Website
- Megabus
Bus from Port Authority Bus Terminal to Pittsburgh Greyhound
- Ave. Duration
- 7h 45m
- Frequency
- Once daily
- Estimated price
- $50–80
- Website
- Megabus
- Adult One-way
- $50–80
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Booking & Getting There
Saco to Pittsburgh bus services, operated by Biddeford Saco Old Orchard Beach Transit, arrive at St John St station.
Saco to Pittsburgh train services, operated by Amtrak, arrive at Boston station.
Yes, the driving distance between Saco to Pittsburgh is 656 miles. It takes approximately 11h 48m to drive from Saco to Pittsburgh.
Book your Saco to Pittsburgh train tickets online with Omio.
There are 649+ hotels available in Pittsburgh.
















