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How to get fromSaco to Chicagoby plane, train (Amtrak), bus (Flixbus), car, train, or bus

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There are 9 ways to get from Saco to Chicago by plane, train (Amtrak), bus (Flixbus), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Portland to Chicago Midway International Airport

    best
    1. Fly from Portland (PWM) to Chicago Midway International Airport (MDW)plane plane PWM - MDW
    5h 58m
    $121–623

  2. Fly Portland to Chicago O'Hare International Airport

    cheapest
    1. Fly from Portland (PWM) to Chicago O'Hare International Airport (ORD)plane plane PWM - ORD
    6h 27m
    $96–443

  3. Train (Amtrak)

    1. Take the train from Saco Amtrak Station to Bostontrain train Downeaster
    2. Take the train from Boston to Chicago Union Stationtrain train Lake Shore Limited
    25h 36m
    $344–716

  4. Bus

    1. Take the bus from Dyer Library to St John Stbus bus 60
    2. Take the bus from City of Portland to New York Midtownbus bus
    3. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    32h 50m
    $187–317

  5. Drive 1,020.7 mi

    1. Drive from Saco to Chicagocar car 1,020.7 mi
    19h
    $187–270

  6. Train to Boston Logan Airport, fly to Chicago Midway International Airport

    1. Take the train from Saco Amtrak Station to Woburn Amtrak Stationtrain train
    2. Fly from Boston Logan Airport (BOS) to Chicago Midway International Airport (MDW)plane plane BOS - MDW
    7h 1m
    $123–489

  7. Train to Boston Logan Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Saco Amtrak Station to Woburn Amtrak Stationtrain train
    2. Fly from Boston Logan Airport (BOS) to Chicago O'Hare International Airport (ORD)plane plane BOS - ORD
    7h 22m
    $138–669

  8. Train, bus to Manchester Airport, fly to Chicago Midway International Airport

    1. Take the train from Saco Amtrak Station to Bostontrain train
    2. Take the bus from Boston to Boston Manchester Airportbus bus
    3. Fly from Manchester Airport (MHT) to Chicago Midway International Airport (MDW)plane plane MHT - MDW
    8h 33m
    $133–546

  9. Train, bus to Manchester Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Saco Amtrak Station to Bostontrain train
    2. Take the bus from Boston to Boston Manchester Airportbus bus
    3. Fly from Manchester Airport (MHT) to Chicago O'Hare International Airport (ORD)plane plane MHT - ORD
    9h 8m
    $113–436

Saco to Chicago by train and subway (Amtrak)

Calendar7Weekly Services
Duration25h 36mAverage Duration
Ticket$344Cheapest Price
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Questions & Answers

Map of how to get from Saco to Chicago.ExpandLaunch map view
  • Distance: 925.8 mi
  • Duration: 5h 58m

What companies run services between Saco, ME, USA and Chicago, IL, USA?

Southwest Airlines flies from Portland (PWM) to Chicago Midway International Airport (MDW) 3 times a day. Alternatively, you can take a train from Saco Amtrak Station to Chicago Union Station via Boston, North Station, Back Bay, and Boston in around 25h 36m.

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Want to know more about travelling around United States

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