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How to get fromSaco to Chicagoby plane, train (Amtrak), train, bus or car

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There are 9 ways to get from Saco to Chicago by plane, train (Amtrak), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Portland to Chicago Midway International Airport

    best
    1. Fly from Portland (PWM) to Chicago Midway International Airport (MDW)planePWM - MDW
    6h 4m
    $120–617
  2. Fly Portland to Chicago O'Hare International Airport

    cheapest
    1. Fly from Portland (PWM) to Chicago O'Hare International Airport (ORD)planePWM - ORD
    6h 30m
    $90–437
  3. Train (Amtrak)

    1. Take the train from Saco Amtrak Station to BostontrainDowneaster
    2. Take the train from Boston to Chicago Union StationtrainLake Shore Limited
    25h 37m
    $169–736
  4. Train, bus

    1. Take the train from Saco Amtrak Station to Bostontrain
    2. Take the bus from Boston, MA to Port Authority Bus Terminalbus
    3. Take the bus from Port Authority Bus Terminal to Newark Penn Stationbus108
    4. Take the bus from Newark Penn Station to Chicago Bus Stationbus
    29h 17m
    $155–351
  5. Drive 1,021.5 mi

    1. Drive from Saco to Chicagocar1,021.5 mi
    18h 48m
    $187–270
  6. Train to Boston Logan Airport, fly to Chicago Midway International Airport

    1. Take the train from Saco Amtrak Station to Woburn Amtrak Stationtrain
    2. Fly from Boston Logan Airport (BOS) to Chicago Midway International Airport (MDW)planeBOS - MDW
    7h 10m
    $107–529
  7. Train to Boston Logan Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Saco Amtrak Station to Woburn Amtrak Stationtrain
    2. Fly from Boston Logan Airport (BOS) to Chicago O'Hare International Airport (ORD)planeBOS - ORD
    7h 27m
    $122–389
  8. Train, bus to Manchester Airport, fly to Chicago Midway International Airport

    1. Take the train from Saco Amtrak Station to Bostontrain
    2. Take the bus from Boston to Boston Manchester Airportbus
    3. Fly from Manchester Airport (MHT) to Chicago Midway International Airport (MDW)planeMHT - MDW
    8h 42m
    $154–667
  9. Train, bus to Manchester Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Saco Amtrak Station to Bostontrain
    2. Take the bus from Boston to Boston Manchester Airportbus
    3. Fly from Manchester Airport (MHT) to Chicago O'Hare International Airport (ORD)planeMHT - ORD
    9h 10m
    $124–477

Saco to Chicago by train and subway (Amtrak)

Calendar7Weekly Services
Duration25h 37mAverage Duration
Ticket$169Cheapest Price
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Questions & Answers

What companies run services between Saco, ME, USA and Chicago, IL, USA?

Southwest Airlines flies from Portland (PWM) to Chicago Midway International Airport (MDW) twice daily. Alternatively, you can take a train from Saco Amtrak Station to Chicago Union Station via Boston, North Station, Back Bay, and Boston in around 25h 37m.

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