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How to get fromSaco to Buffaloby train, plane, bus, train (Amtrak), car or bus (Amtrak, Flixbus, Greyhound)

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There are 7 ways to get from Saco to Buffalo by train, plane, bus, train (Amtrak), car, or bus (Amtrak, Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Boston Logan Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Saco Amtrak Station to Woburn Amtrak Stationtrain train
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    6h 39m
    $189–1,071

  2. Train, bus

    cheapest
    1. Take the train from Saco Amtrak Station to Bostontrain train
    2. Take the bus from Boston, MA to Syracuse, NYbus bus
    3. Take the bus from Syracuse, NY to Buffalo, NYbus bus
    14h 42m
    $72–193

  3. Train (Amtrak)

    1. Take the train from Saco Amtrak Station to Bostontrain train Downeaster
    2. Take the train from Boston to Buffalo Depew Stationtrain train Lake Shore Limited
    16h 15m
    $89–281

  4. Drive 494.2 mi

    1. Drive from Saco to Buffalocar car 494.2 mi
    10h 2m
    $91–131

  5. Fly Portland to Buffalo Niagara International Airport

    1. Fly from Portland (PWM) to Buffalo Niagara International Airport (BUF)plane plane PWM - BUF
    8h 10m
    $232–1,392

  6. Train to Boston Logan Airport, fly to Rochester, bus

    1. Take the train from Saco Amtrak Station to Woburn Amtrak Stationtrain train
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the bus from Rochester, NY to Buffalo, NYbus bus
    8h 40m
    $249–726

  7. Bus

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to Syracuse Bus Stationbus bus
    3. Take the bus from Syracuse Bus Station to Buffalobus bus
    15h 9m
    $95–226

Saco to Buffalo by train, tram, and bus

Calendar2Weekly Services
Duration14h 42mAverage Duration
Ticket$72Cheapest Price
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Questions & Answers

What companies run services between Saco, ME, USA and Buffalo, NY, USA?

You can take a train from Saco Amtrak Station to Buffalo via Boston, North Station, Back Bay, Boston, and Buffalo Depew Station in around 16h 15m. Alternatively, Delta, United Airlines, and two other airlines fly from Portland (PWM) to Buffalo Niagara International Airport (BUF) hourly.

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Need to know: Greyhound

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