There are 7 ways to get from Rome to Mytilene by plane, train, bus, ferry, car, car ferry, or busferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Mytilene International Airport Odysseas Elytis
best- Fly from Fiumicino International Airport (FCO) to Mytilene International Airport Odysseas Elytis (MJT)plane FCO - MJT
6h 39m€112–236Train, bus, ferry
- Take the train from Roma Termini to Bologna centraletrain
- Take the bus from Bologna Centrale to Skopje, Transporten Centarbus
- Take the bus from Skopje, Transporten Centar to Thessaloníkibus
- Take the ferry from Thessaloniki to Mytileneferry Bsf
34h 1m€251–373Drive, car ferry, ferry
- Drive from Rome to Port Of Anconacar
- Take the car ferry from Port of Ancona to Durrëscarferry
- Drive from Port Of Durres to Thessalonikicar
- Take the ferry from Thessaloniki to Mytileneferry Bsf
- Take the ferry from Mytilene to Port of Ayvalikferry
- Take the car ferry from Port of Ayvalik to Mytilenecarferry
39h 52m€331–548Fly to Chios Airport, ferry
- Fly from Fiumicino International Airport (FCO) to Chios Airport (JKH)plane FCO - JKH
- Take the ferry from Chios to Mytileneferry
10h 45m€146–382Bus, ferry via Kavála
- Take the bus from Roma Termini to Kumanovobus
- Take the bus from Kumanovo to Thessaloniki Macedonia KTEL Bus Stationbus
- Take the bus from Thessaloniki Macedonia KTEL Bus Station to Kavalabus
- Take the ferry from Kavala to Mytileneferry Bsf
37h 55m€191–273Bus and ferry, bus, ferry
- Take the busferry from Roma, Autostazione Tiburtina to Elbasanbusferry
- Take the bus from Elbasan to Thessaloníkibus
- Take the ferry from Thessaloniki to Mytileneferry Bsf
38h 13mBus, ferry
- Take the bus from Roma Termini to Skopje, Transporten Centarbus
- Take the bus from Skopje Central Bus Station to Thessalonikibus
- Take the ferry from Thessaloniki to Mytileneferry Bsf
38h 16m€195–285
Fiumicino International Airport (FCO) to Mytilene International Airport Odysseas Elytis (MJT) flights
Questions & Answers
The cheapest way to get from Rome to Mytilene is to fly which costs €110 - €240 and takes 6h 39m.
The fastest way to get from Rome to Mytilene is to fly which takes 6h 39m and costs €110 - €240.
The distance between Rome and Mytilene is 1291 km.
The best way to get from Rome to Mytilene without a car is to train and bus and ferry which takes 34h 1m and costs €250 - €380.
It takes approximately 6h 39m to get from Rome to Mytilene, including transfers.
Mytilene is 1h ahead of Rome. It is currently 7:05 AM in Rome and 8:05 AM in Mytilene.
There are 79+ hotels available in Mytilene.
What companies run services between Rome, Italy and Mytilene, Greece?
ITA Airways, Sky Express, and three other airlines fly from Fiumicino International Airport (FCO) to Mytilene International Airport Odysseas Elytis (MJT) 5 times a day.
- Website
- en.aegeanair.com
Flights from Fiumicino International Airport to Mytilene International Airport Odysseas Elytis via Athens
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- €110–210
Flights from Fiumicino International Airport to Chios Airport via Athens
- Ave. Duration
- 6h 57m
- When
- Every day
- Estimated price
- €55–650
- Website
- skyexpress.gr
Flights from Fiumicino International Airport to Mytilene International Airport Odysseas Elytis via Athens
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- €100–200
Flights from Fiumicino International Airport to Chios Airport via Athens
- Ave. Duration
- 6h 46m
- When
- Every day
- Estimated price
- €55–320
- Website
- transavia.com
Flights from Fiumicino International Airport to Mytilene International Airport Odysseas Elytis via Skiathos
- Ave. Duration
- 4h 10m
- When
- Monday
- Estimated price
- €110–200
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Roma Termini to Bologna centrale
- Ave. Duration
- 2h 3m
- Frequency
- Every 20 minutes
- Estimated price
- €45–90
- Website
- https://www.italotreno.it/en
- Phone
- +389 75 209 209
- hakkomerc@gmail.com
- Website
- hakbus.org
Bus from Bologna Centrale to Skopje, Transporten Centar
- Ave. Duration
- 14h 48m
- Frequency
- Once a week
- Estimated price
- €110
- Website
- https://www.hakbus.org/
Bus from Roma Termini to Kumanovo
- Ave. Duration
- 21h 36m
- Frequency
- Once a week
- Estimated price
- €110
- Website
- https://www.hakbus.org/
Bus from Roma Termini to Skopje, Transporten Centar
- Ave. Duration
- 22h 1m
- Frequency
- Once a week
- Estimated price
- €110
- Website
- https://www.hakbus.org/
- Phone
- +389 2 240 2528
- ruleturs@sas.com.mk
- Website
- ruleturs.mk
Bus from Skopje, Transporten Centar to Thessaloníki
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a week
- Estimated price
- €35
- Schedules at
- ruleturs.mk
- Phone
- 0030 2108219900
- vsiamos@otenet.gr
- Website
- siamostours.com
Bus from Kumanovo to Thessaloniki Macedonia KTEL Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a week
- Estimated price
- €24
- Schedules at
- siamostours.com
- Phone
- +30 2510.222294
- info@ktelkavalas.gr
- Website
- ktelkavalas.gr
Bus from Thessaloniki Macedonia KTEL Bus Station to Kavala
- Ave. Duration
- 2h 10m
- Frequency
- Every 2 hours
- Estimated price
- €12–19
- Schedules at
- ktelkavalas.gr
- Phone
- +393293958604
- info@pistoiaviaggi.com
- Website
- pistoia-viaggi.it
Busferry from Roma, Autostazione Tiburtina to Elbasan
- Ave. Duration
- 18h 6m
- Frequency
- Once a week
- Schedules at
- pistoia-viaggi.it
- Phone
- +355 67 604 2191
- Website
- facebook.com
Bus from Elbasan to Thessaloníki
- Ave. Duration
- 7h 43m
- Frequency
- Twice daily
- Schedules at
- autobus.al
- Phone
- +30-2310540970
- info@simeonidistours.gr
- Website
- simeonidistours.gr
Bus from Skopje Central Bus Station to Thessaloniki
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- €25–35
- Website
- https://simeonidistours.gr/en/
Ferry from Thessaloniki to Mytilene
- Ave. Duration
- 10h 5m
- Frequency
- Twice a week
- Estimated price
- €60–140
- Website
- https://www.bluestarferries.com/en-gb/
Ferry from Chios to Mytilene
- Ave. Duration
- 2h 25m
- Frequency
- 4 times a week
- Estimated price
- €17–40
- Website
- https://www.bluestarferries.com/en-gb/
Ferry from Kavala to Mytilene
- Ave. Duration
- 7h 30m
- Frequency
- 4 times a week
- Estimated price
- €50–120
- Website
- https://www.bluestarferries.com/en-gb/
- Phone
- +3907150211621
- booking@adriaferries.com
- Website
- adriaferries.com
Car ferry from Port of Ancona to Durrës
- Ave. Duration
- 16h
- Frequency
- Once daily
- Estimated price
- €90–150
- Schedules at
- adriaferries.com
- Deck
- €95
- Inside cabin 2 beds
- €125
- Inner cabin 2 beds
- €145
- Car
- €130
- Phone
- 0545 783 50 61
- info@jalemtur.com
- Website
- jalemtur.com
Ferry from Mytilene to Port of Ayvalik
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- €30–40
- Schedules at
- jalemtur.com
- Phone
- +90 266 331 49 49
- info@ugurjale.com
- Website
- ugurjalelines.com
Car ferry from Port of Ayvalik to Mytilene
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- €29–30
- Schedules at
- ugurjalelines.com
Ferry from Chios to Mytilene
- Ave. Duration
- 3h
- Frequency
- 6 times a week
- Estimated price
- €35–50
- Website
- https://www.hellenicseaways.gr/en-gb
- Airplane Type Seats
- €35–50
Ferry from Kavala to Mytilene
- Ave. Duration
- 9h 35m
- Frequency
- Once a week
- Estimated price
- €45–65
- Website
- https://www.hellenicseaways.gr/en-gb
- Airplane Type Seats
- €45–65
Want to know more about travelling around Greece
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