Travel from Italy to Greece is: Unrestricted. See details.
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There are 5 ways to get from Rome to Mytilene by plane, ferry, train, bus or car ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Mytilini  •  6h 55m

  1. Fly from Rome (FCO) to Mytilini (MJT) FCO - MJT

4 alternative options

Fly to Chios, ferry  •  10h 35m

  1. Fly from Rome (FCO) to Chios (JKH) FCO - JKH
  2. Take the ferry from Chios to Mytilene

Train, ferry, bus  •  31h 32m

  1. Take the train from Roma Termini to Bari Centrale Fa / ...
  2. Take the ferry from Bari M.ma to Igoumenitsa Asf
  3. Take the bus from Igoumenitsa to Thessaloniki
  4. Take the ferry from Thessaloniki to Mytilene Bsf

Bus, ferry  •  44h 22m

  1. Take the bus from Roma to Sofia
  2. Take the bus from Sofia to Kavala
  3. Take the ferry from Kavala to Mytilene Bsf

Bus, car ferry  •  2 days 1h

  1. Take the bus from Roma to Sofia
  2. Take the bus from Sofia Serdica Bus Station to Bursa Terminal Bus
  3. Take the bus from Bursa to Ayvalık
  4. Take the car ferry from Ayvalık to Mytilene
Italy → Greece
Unrestricted

Travel safe during COVID-19

International entry into Greece from Italy

  • Entry is unrestricted for citizens and permanent residents of Italy
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Allowed for: All visitors

Restricted for: There are no current restrictions

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Conditions of entry into Greece from Italy

  • There are no current restrictions
This applies to arrivals from all countries, with no exceptions

Rules to follow in Greece

m

Mandatory

Mandatory

Considerations leaving from Italy

There are no current restrictions

Frequently Asked Questions


Yes, entry into Greece is currently allowed from Italy.

Explore travel options

Domestic travel is not restricted, but some conditions may apply

  • Face masks are mandatory
  • Observe COVID-19 safety rules

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The national COVID-19 helpline number in Mytilene is 210 521 2054.

Wearing a face mask on public transport in Mytilene is mandatory.

Make yourself known to an official member of staff and/or call the national coronavirus helpline number on 210 521 2054.

No, returning to Italy from Greece is currently allowed.

See options for return travel.

Last updated: 3 Oct 2022
Exceptions may apply, for full details: European Union.

We're working around the clock to bring you the latest COVID-19 travel updates.
This information is compiled from official sources. To the best of our knowledge, it is correct as of the last update.
Visit Rome2rio travel advice for general help.

Questions & Answers

The cheapest way to get from Rome to Mytilene is to fly which costs €110 - €650 and takes 6h 55m.

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The quickest way to get from Rome to Mytilene is to fly which costs €110 - €650 and takes 6h 55m.

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The distance between Rome and Mytilene is 1227 km.

The best way to get from Rome to Mytilene without a car is to train and ferry and bus which takes 31h 32m and costs €180 - €500.

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It takes approximately 6h 55m to get from Rome to Mytilene, including transfers.

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There is no direct flight from Rome Airport to Mytilini Airport. The quickest flight takes 4h 15m and has one stopover.

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Mytilene is 1h ahead of Rome. It is currently 7:03 AM in Rome and 8:03 AM in Mytilene.

Brussels Airlines, Alitalia, Sky Express and Aegean Airlines offer flights from Rome Airport to Mytilini Airport.

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There are 58+ hotels available in Mytilene. Prices start at €100 per night.

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The best way to get from Rome to Rome Airport is to train which takes 32 min and costs €7 - €35.

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Map of how to get from Rome to Mytilene.
Launch map view
  • Distance: 1226.6 km
  • Duration: 6h 55m

What companies run services between Rome, Italy and Mytilene, Greece?

Aegean Airlines, Sky Express and three other airlines fly from Rome to Mytilene every 4 hours.

Airlines
Sky Express
Website
skyexpress.gr
Flights from Rome to Mytilini via Athens
Ave. Duration
5h 26m
When
Every day
Estimated price
€120 - €650
Flights from Rome to Mytilini via Thessaloniki
Ave. Duration
5h 15m
When
Wednesday
Estimated price
€110 - €1000
Flights from Rome to Chios via Athens
Ave. Duration
5h 52m
When
Every day
Estimated price
€85 - €390
Flights from Rome to Chios via Thessaloniki
Ave. Duration
5h
When
Wednesday
Estimated price
€160 - €440
Flights from Rome to Chios via Athens, Mytilini
Ave. Duration
6h 40m
When
Monday and Wednesday
Estimated price
€160 - €440
Aegean Airlines
Website
en.aegeanair.com
Flights from Rome to Mytilini via Athens
Ave. Duration
4h 15m
When
Every day
Estimated price
€110 - €1000
Flights from Rome to Mytilini via Thessaloniki, Athens
Ave. Duration
9h 15m
When
Wednesday
Estimated price
€110 - €1000
Flights from Rome to Chios via Athens
Ave. Duration
4h 10m
When
Every day
Estimated price
€55 - €320
Flights from Rome to Chios via Thessaloniki, Athens
Ave. Duration
8h
When
Wednesday and Saturday
Estimated price
€160 - €440
Olympic Air
Website
olympicair.com
Flights from Rome to Chios via Athens
Ave. Duration
4h 10m
When
Every day
Estimated price
€55 - €320
Brussels Airlines
Website
brusselsairlines.com
Flights from Rome to Mytilini via Brussels
Ave. Duration
8h 35m
When
Friday
Estimated price
€250 - €1100
Train operators
Trenitalia Frecce

Trenitalia’s high-speed Frecce trains run on specialised tracks and have a greater level of service and comfort than InterCity and regional trains. There are three types of Frecce trains: Frecciarossa, (the fastest; connects major Italian cities); Frecciargento (mostly connect Rome to other Italian cities); and Frecciabianca (the slowest Frecce trains). Frecciarossa trains offer four classes of service, all with free Wi-Fi: Standard, Premium, Business and Executive. All Frecce tickets include a seat reservation and must be purchased before boarding the train.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Roma Termini to Bari Centrale
Ave. Duration
4h 5m
Frequency
Every 4 hours
Estimated price
€35 - €110
Website
Trenitalia Frecce
Super Economy
€35 - €50
Base Standard
€60 - €85
Base Premium
€75 - €110
ItaloTreno

Private train company Italotreno operates high-speed trains in Italy on the same tracks as Trenitalia. The routes service 21 stations across the country, including popular routes Milan-Florence, Rome-Venice and Bologna-Naples. Choose from four classes of service, all with free Wi-Fi: Smart, Comfort, Prima and Club Executive. Italo also operates Italobus – an integrated train-bus service that takes passengers from the main train stations to other Italian cities.

Contact Details
Phone
+39 060708
Website
italotreno.it
Train from Roma Termini to Bari Centrale
Ave. Duration
4h 20m
Frequency
3 times a day
Estimated price
€28 - €80
Website
Italo Treno
Smart Economy
€30 - €45
Smart Low Cost
€28 - €40
Smart Flex
€55 - €80
Trenitalia Intercity

Trenitalia’s Intercity (IC) trains are slower than the high-speed Frecce trains but are still a good way to travel between major cities and towns, with routes including Rome to Naples, Venice to Bologna and Milan to Genoa. Tickets usually open for booking 90 days ahead of travel, and you’ll need make a seat reservation before boarding. All IC trains have 1st and 2nd class carriages as well as a bar buffet car, air conditioning and power sockets. InterCity trains that run at night are called InterCity Notte (ICN).

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Roma Termini to Bari Centrale
Ave. Duration
6h 23m
Frequency
Once daily
Estimated price
€29 - €45
Website
Trenitalia Intercity
2nd Class
€29 - €45
Bus operators
KTEL Thesprotias
Phone
2665 0 22309
Email
info@ktel-thesprotias.gr
Website
ktel-thesprotias.gr
Bus from Igoumenitsa to Thessaloniki
Ave. Duration
5h
Frequency
Twice daily
Estimated price
€30 - €45
Website
KTEL Thesprotias
Georg
Phone
+ 359/38/66 34 04
Email
georg_ltd@abv.bg
Website
georg-bg.com
Bus from Roma to Sofia
Ave. Duration
28h 30m
Frequency
Once a week
Estimated price
€190 - €240
Schedules at
georg-bg.com
Kaleia
Phone
+359 894 77 44 02
Email
office@kaleiatravel.com
Website
kaleiatravel.com
Bus from Sofia to Kavala
Ave. Duration
6h
Frequency
Once daily
Schedules at
en.kaleiatravel.com
Ferry operators
Blue Star Ferries
Phone
+30-210-8919800
Email
bluestarferries@bluestarferries.com
Website
bluestarferries.com
Ferry from Chios to Mytilene
Ave. Duration
3h
Frequency
6 times a week
Estimated price
€25 - €80
Website
Blue Star Ferries
Business
€47 - €51
2 Bed Inside Cabin
€55 - €70
Economy
€25 - €35
4 Bed Outside Cabin
€45 - €55
2 Bed Lux Cabin
€60 - €80
Ferry from Thessaloniki to Mytilene
Ave. Duration
9h 55m
Frequency
Once a week
Estimated price
€40 - €110
Website
Blue Star Ferries
Business
€57 - €61
2 Bed Inside Cabin
€70 - €85
Economy
€40 - €55
4 Bed Outside Cabin
€65 - €80
2 Bed Lux Cabin
€85 - €110
Ferry from Kavala to Mytilene
Ave. Duration
7h 45m
Frequency
Once a week
Estimated price
€35 - €100
Website
Blue Star Ferries
Business
€54 - €58
2 Bed Inside Cabin
€65 - €80
Economy
€35 - €50
4 Bed Outside Cabin
€60 - €70
2 Bed Lux Cabin
€80 - €100
Hellenic Seaways
Phone
+30 210 4199000
Email
hswroro@hsw.gr
Website
hellenicseaways.gr
Ferry from Chios to Mytilene
Ave. Duration
2h 55m
Frequency
Once a week
Estimated price
€20 - €75
Website
Hellenic Seaways
Business
€35 - €50
2 Bed Lux Cabin
€55 - €75
Economy
€20 - €26
4 Bed Inside Cabin
€35 - €55
Superfast ferries
Phone
+30 210 8919700
Email
superfast@superfast.com
Website
superfast.com
Ferry from Bari M.ma to Igoumenitsa
Ave. Duration
9h
Frequency
Once daily
Estimated price
€75 - €220
Website
Superfast ferries
Deck
€80
Aircraft-type seats
€88
2 bed inside cabin
€214
3 bed outside cabin
€170 - €210
Turyol
Phone
+90 212 251 4421
Email
cesme@turyol.com
Website
turyolonline.com
Car ferry from Ayvalık to Mytilene
Ave. Duration
1h 30m
Frequency
3 times a week
Estimated price
€20
Schedules at
turyolonline.com

Want to know more about travelling around Greece

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