There are 7 ways to get from Rome to Mytilene by plane, train, busferry, bus, car ferry, ferry, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Mytilene International Airport Odysseas Elytis
best- Fly from Fiumicino International Airport (FCO) to Mytilene International Airport Odysseas Elytis (MJT)plane FCO - MJT
6h 49m€112–267Train, bus and ferry, bus, car ferry
- Take the train from Roma Termini to Brindisitrain Fa / ...
- Take the busferry from Brindisi - Piazza Capitanerie di Porto to Vlorëbusferry
- Take the bus from Vlore , station to Ioanninabus
- Take the bus from Ioannina to Thessaloniki Macedonia KTEL Bus Stationbus
- Take the car ferry from Port of Thessaloniki to Mytilenecarferry
28h 8mTrain, ferry, bus, car ferry
- Take the train from Roma Termini to Bari Centraletrain
- Take the ferry from Bari M.ma to Igoumenitsaferry Asf
- Take the bus from Igoumenitsa to Thessaloniki Macedonia KTEL Bus Stationbus
- Take the car ferry from Port of Thessaloniki to Mytilenecarferry
29h 22m€298–694Bus, car ferry
- Take the bus from Roma Termini to Skopje, Transporten Centarbus
- Take the bus from Skopje Central Bus Station to Thessalonikibus
- Take the car ferry from Port of Thessaloniki to Mytilenecarferry
35h 22m€270–515Fly to Chios Airport, ferry
- Fly from Fiumicino International Airport (FCO) to Chios Airport (JKH)plane FCO - JKH
- Take the ferry from Chios to Mytileneferry
10h 25m€126–343Drive, car ferry
- Drive from Rome to Port Of Anconacar
- Take the car ferry from Port of Ancona to Durrëscarferry
- Drive from Port Of Durres to Port of Thessalonikicar
- Take the car ferry from Port of Thessaloniki to Mytilenecarferry
32h 49m€343–709Bus and ferry, bus, ferry
- Take the busferry from Roma, Autostazione Tiburtina to Elbasanbusferry
- Take the bus from Elbasan to Thessaloníkibus
- Take the ferry from Thessaloniki to Mytileneferry Bsf
38h 3m
Fiumicino International Airport (FCO) to Mytilene International Airport Odysseas Elytis (MJT) flights
Questions & Answers
The cheapest way to get from Rome to Mytilene is to fly which costs €110 - €270 and takes 6h 49m.
The fastest way to get from Rome to Mytilene is to fly which takes 6h 49m and costs €110 - €270.
The distance between Rome and Mytilene is 1291 km.
The best way to get from Rome to Mytilene without a car is to train and bus and ferry and bus and car ferry which takes 28h 8m and costs .
It takes approximately 6h 49m to get from Rome to Mytilene, including transfers.
Mytilene is 1h ahead of Rome. It is currently 6:45 AM in Rome and 7:45 AM in Mytilene.
There are 464+ hotels available in Mytilene.
What companies run services between Rome, Italy and Mytilene, Greece?
Aegean Airlines, ITA Airways, and three other airlines fly from Fiumicino International Airport (FCO) to Mytilene International Airport Odysseas Elytis (MJT) 4 times a day.
- Website
- en.aegeanair.com
Flights from Fiumicino International Airport to Mytilene International Airport Odysseas Elytis via Athens
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- €50–240
Flights from Fiumicino International Airport to Mytilene International Airport Odysseas Elytis via Thessaloniki
- Ave. Duration
- 4h 25m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €110–240
Flights from Fiumicino International Airport to Chios Airport via Athens
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- €50–250
Flights from Fiumicino International Airport to Chios Airport via Thessaloniki
- Ave. Duration
- 8h
- When
- Monday and Friday
- Estimated price
- €110–250
- Website
- skyexpress.gr
Flights from Fiumicino International Airport to Mytilene International Airport Odysseas Elytis via Athens
- Ave. Duration
- 7h 10m
- When
- Every day
- Estimated price
- €100–250
Flights from Fiumicino International Airport to Chios Airport via Athens
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- €50–250
- Website
- transavia.com
Flights from Fiumicino International Airport to Mytilene International Airport Odysseas Elytis via Skiathos
- Ave. Duration
- 4h 10m
- When
- Monday
- Estimated price
- €50–200
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Brindisi
- Ave. Duration
- 5h 23m
- Frequency
- 5 times a day
- Estimated price
- €80–160
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Roma Termini to Bari Centrale
- Ave. Duration
- 4h 20m
- Frequency
- Once daily
- Estimated price
- €60–120
- Website
- https://www.italotreno.it/en
- Phone
- +393293958604
- info@pistoiaviaggi.com
- Website
- pistoia-viaggi.it
Busferry from Brindisi - Piazza Capitanerie di Porto to Vlorë
- Ave. Duration
- 4h 28m
- Frequency
- Once a week
- Schedules at
- pistoia-viaggi.it
Busferry from Roma, Autostazione Tiburtina to Elbasan
- Ave. Duration
- 18h 6m
- Frequency
- Once a week
- Schedules at
- pistoia-viaggi.it
- Phone
- +355 69 661 4303
- likospartak@gmail.com
- Website
- likokostatours.weebly.com
Bus from Vlore , station to Ioannina
- Ave. Duration
- 3h 7m
- Frequency
- Once daily
- Schedules at
- facebook.com
- Phone
- +30 26510 25014
- ktelioa@otenet.gr
- Website
- ktelioannina.gr
Bus from Ioannina to Thessaloniki Macedonia KTEL Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- 5 times a day
- Estimated price
- €24–35
- Schedules at
- ktelioannina.gr
- Book at
- eticket.ktelioannina.gr
- Phone
- +30 2665 0 22309
- info@ktel-thesprotias.gr
- Website
- ktel-thesprotias.gr
Bus from Igoumenitsa to Thessaloniki Macedonia KTEL Bus Station
- Ave. Duration
- 5h
- Frequency
- Twice daily
- Estimated price
- €35–55
- Schedules at
- ktel-thesprotias.gr
- Book at
- ktelbus.gr
- Phone
- +389 75 209 209
- hakkomerc@gmail.com
- Website
- hakbus.org
Bus from Roma Termini to Skopje, Transporten Centar
- Ave. Duration
- 22h 1m
- Frequency
- Once a week
- Estimated price
- €110
- Website
- https://www.hakbus.org/
- Phone
- +30-2310540970
- info@simeonidistours.gr
- Website
- simeonidistours.gr
Bus from Skopje Central Bus Station to Thessaloniki
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- €20–35
- Schedules at
- simeonidistours.gr
- Phone
- +355 67 604 2191
- Website
- facebook.com
Bus from Elbasan to Thessaloníki
- Ave. Duration
- 7h 43m
- Frequency
- Twice daily
- Schedules at
- autobus.al
- Phone
- +30 210 710 7 710
- reservations.dpt@seajets.gr
- Website
- seajets.com
Car ferry from Port of Thessaloniki to Mytilene
- Ave. Duration
- 7h 10m
- Frequency
- Once a week
- Estimated price
- €140–370
- Website
- https://www.seajets.com/
Ferry from Bari M.ma to Igoumenitsa
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- €55–140
- Website
- https://www.bluestarferries.com/en-gb/
Ferry from Chios to Mytilene
- Ave. Duration
- 2h 25m
- Frequency
- Twice a week
- Estimated price
- €17–40
- Website
- https://www.bluestarferries.com/en-gb/
Ferry from Thessaloniki to Mytilene
- Ave. Duration
- 9h 55m
- Frequency
- Once a week
- Estimated price
- €65–160
- Website
- https://www.bluestarferries.com/en-gb/
Ferry from Chios to Mytilene
- Ave. Duration
- 3h
- Frequency
- 6 times a week
- Estimated price
- €35–50
- Website
- https://www.hellenicseaways.gr/en-gb
- Airplane Type Seats
- €35–50
- Phone
- +3907150211621
- booking@adriaferries.com
- Website
- adriaferries.com
Car ferry from Port of Ancona to Durrës
- Ave. Duration
- 16h
- Frequency
- Once daily
- Estimated price
- €80–145
- Schedules at
- adriaferries.com
- Deck
- €95
- Inside cabin 2 beds
- €125
- Inner cabin 2 beds
- €145
- Car
- €130
Want to know more about travelling around Greece
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