Rome2Rio

How to get fromRome to Medeby train, bus, car, plane, or train (Trenitalia)

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There are 9 ways to get from Rome to Mede by train, bus, car, plane, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Roma Termini to Milano Centraletrain train 9950 / ...
    5h 44m
    €80–158

  2. Bus

    cheapest
    1. Take the bus from Roma, Autostazione Tiburtina to Alessandriabus bus N503
    10h 14m
    €45–80

  3. Drive 594.8 km

    1. Drive from Rome to Medecar car 594.8 km
    5h 40m
    €94–135

  4. Fly to Milan Linate Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Milan Linate Airport (LIN)plane plane FCO - LIN
    2. Take the train from Milano Dateo to Paviatrain train
    3. Take the train from Pavia to Medetrain train
    5h 31m
    €60–176

  5. Train via Milan

    1. Take the train from Roma Termini to Milan Rogoredotrain train 9962
    7h 6m
    €75–174

  6. Train #2 (Trenitalia)

    1. Take the train from Roma Termini to Alessandriatrain train Fr
    7h 19m
    €63–166

  7. Fly to Genoa Cristoforo Colombo Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Genoa Cristoforo Colombo Airport (GOA)plane plane FCO - GOA
    2. Take the train from Genova P.Za Principe to Alessandriatrain train
    6h 25m
    €59–185

  8. Fly to Turin Caselle Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Turin Caselle Airport (TRN)plane plane FCO - TRN
    2. Take the train from Torino Lingotto to Alessandriatrain train
    6h 39m
    €53–190

  9. Fly to Milano Malpensa Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Milano Malpensa Airport (MXP)plane plane FCO - MXP
    2. Take the train from Malpensa Aeroporto T1 to Milano Bovisa Politecnicotrain train
    3. Take the train from Milano Bovisa Politecnico to Paviatrain train
    6h 22m
    €59–170

Rome to Mede by bus

Calendar6Weekly Buses
Duration10h 14mAverage Duration
Ticket€45Cheapest Price
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Questions & Answers

Map of how to get from Rome to Mede.ExpandLaunch map view
  • Distance: 653.1 km
  • Duration: 5h 44m

What companies run services between Rome, Italy and Mede, Italy?

ItaloTreno operates a train from Roma Termini to Milano Centrale every 30 minutes. Tickets cost €70–150 and the journey takes 3h 5m. Alternatively, FlixBus operates a bus from Roma, Autostazione Tiburtina to Alessandria once daily. Tickets cost €45–80 and the journey takes 8h 30m.

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