There are 8 ways to get from Rome to Mede by train, bus, car, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Roma Termini to Milano Centraletrain 9950 / ...
5h 33m€84–167Bus
cheapest- Take the bus from Roma, Autostazione Tiburtina to Alessandriabus N503
10h 14m€40–75Drive 594.7 km
- Drive from Rome to Medecar 594.7 km
5h 40m€93–134Fly to Milan Linate Airport, train
- Fly from Fiumicino International Airport (FCO) to Milan Linate Airport (LIN)plane FCO - LIN
- Take the train from Milano Dateo to Paviatrain
- Take the train from Pavia to Medetrain
5h 27m€55–157Train via Milan
- Take the train from Roma Termini to Milan Rogoredotrain 9962
5h 43m€80–152Train #2 (Trenitalia)
- Take the train from Roma Termini to Alessandriatrain Fr
7h 9m€61–161Fly to Genoa Cristoforo Colombo Airport, train
- Fly from Fiumicino International Airport (FCO) to Genoa Cristoforo Colombo Airport (GOA)plane FCO - GOA
- Take the train from Genova P.Za Principe to Alessandriatrain
6h 26m€59–156Fly to Turin Caselle Airport, train
- Fly from Fiumicino International Airport (FCO) to Turin Caselle Airport (TRN)plane FCO - TRN
- Take the train from Torino Lingotto to Alessandriatrain
- Take the train from Alessandria to Medetrain
6h 15m€58–191
Rome to Mede by train
Questions & Answers
The cheapest way to get from Rome to Mede is to bus which costs €40 - €75 and takes 10h 14m.
The fastest way to get from Rome to Mede is to fly and train which takes 5h 27m and costs €55 - €160.
No, there is no direct bus from Rome to Mede. However, there are services departing from Roma, Autostazione Tiburtina and arriving at Mede via Alessandria. The journey, including transfers, takes approximately 10h 14m.
No, there is no direct train from Rome to Mede. However, there are services departing from Roma Termini and arriving at Mede via Milano Centrale and Pavia. The journey, including transfers, takes approximately 5h 33m.
The distance between Rome and Mede is 653 km. The road distance is 594.7 km.
The best way to get from Rome to Mede without a car is to train which takes 5h 33m and costs €80 - €170.
It takes approximately 5h 33m to get from Rome to Mede, including transfers.
Rome to Mede bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Rome to Mede train services, operated by ItaloTreno, depart from Roma Termini station.
The best way to get from Rome to Mede is to train which takes 5h 33m and costs €80 - €170. Alternatively, you can bus, which costs €40 - €75 and takes 10h 14m.
What companies run services between Rome, Italy and Mede, Italy?
ItaloTreno operates a train from Roma Termini to Milano Centrale every 30 minutes. Tickets cost €75–160 and the journey takes 3h 5m. Alternatively, FlixBus operates a bus from Roma, Autostazione Tiburtina to Alessandria once daily. Tickets cost €40–75 and the journey takes 8h 30m.
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Milan Linate Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €45–140
Flights from Fiumicino International Airport to Genoa Cristoforo Colombo Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- €40–110
Flights from Fiumicino International Airport to Turin Caselle Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- €45–140
- Website
- aeroitalia.com
Flights from Fiumicino International Airport to Milan Linate Airport via Olbia
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- €100–380
Flights from Fiumicino International Airport to Genoa Cristoforo Colombo Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €40–220
- Website
- flexflight.dk
Flights from Fiumicino International Airport to Milan Linate Airport via Olbia
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- €100–380
Flights from Fiumicino International Airport to Genoa Cristoforo Colombo Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €40–220
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €75–160
- Website
- https://www.italotreno.it/en
Train from Roma Termini to Milan Rogoredo
- Ave. Duration
- 3h 28m
- Frequency
- Once daily
- Estimated price
- €75–150
- Website
- https://www.italotreno.it/en
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Milano Dateo to Pavia
- Ave. Duration
- 39 min
- Frequency
- Every 30 minutes
- Estimated price
- €3–5
- Website
- https://www.trenord.it/en/
Train from Pavia to Mede
- Ave. Duration
- 42 min
- Frequency
- Hourly
- Estimated price
- €2–3
- Website
- https://www.trenord.it/en/
Train from Alessandria to Mede
- Ave. Duration
- 26 min
- Frequency
- Hourly
- Estimated price
- €3–4
- Website
- https://www.trenord.it/en/
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Alessandria
- Ave. Duration
- 5h 48m
- Frequency
- Once daily
- Estimated price
- €80–160
- Schedules at
- trenitalia.com
Train from Genova P.Za Principe to Alessandria
- Ave. Duration
- 42 min
- Frequency
- Once daily
- Estimated price
- €10–20
- Schedules at
- trenitalia.com
Train from Torino Lingotto to Alessandria
- Ave. Duration
- 51 min
- Frequency
- Once daily
- Estimated price
- €12–24
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Alessandria
- Ave. Duration
- 7h 7m
- Frequency
- Once daily
- Estimated price
- €55–130
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Alessandria
- Ave. Duration
- 50 min
- Frequency
- 3 times a day
- Estimated price
- €7–16
- Website
- https://www.trenitalia.com/en.html
Train from Torino Lingotto to Alessandria
- Ave. Duration
- 46 min
- Frequency
- 3 times a day
- Estimated price
- €8–20
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Genova P.Za Principe to Alessandria
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €9–15
- Website
- https://www.trenitalia.com/en.html
Train from Torino Lingotto to Alessandria
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Roma, Autostazione Tiburtina to Alessandria
- Ave. Duration
- 8h 30m
- Frequency
- Once daily
- Estimated price
- €40–75
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Italy
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More Questions & Answers
Rome to Mede bus services, operated by FlixBus, arrive at Alessandria station.
Rome to Mede train services, operated by ItaloTreno, arrive at Milano Centrale station.
Yes, the driving distance between Rome to Mede is 595 km. It takes approximately 5h 40m to drive from Rome to Mede.
Book your Rome to Mede train tickets online with Omio.
There are 306+ hotels available in Mede.

























