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How to get fromRome to Medeby train, bus, car, plane, or train (Trenitalia)

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There are 9 ways to get from Rome to Mede by train, bus, car, plane, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Roma Termini to Milano Centraletrain train 9950 / ...
    5h 23m
    €82–161

  2. Fly to Turin Caselle Airport, train

    cheapest
    1. Fly from Fiumicino International Airport (FCO) to Turin Caselle Airport (TRN)plane plane FCO - TRN
    2. Take the train from Torino Lingotto to Alessandriatrain train
    6h 16m
    €49–200

  3. Bus

    1. Take the bus from Roma, Autostazione Tiburtina to Alessandriabus bus N503
    10h 14m
    €50–85

  4. Drive 594.8 km

    1. Drive from Rome to Medecar car 594.8 km
    5h 40m
    €93–134

  5. Fly to Milan Linate Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Milan Linate Airport (LIN)plane plane FCO - LIN
    2. Take the train from Pavia to Medetrain train
    5h 34m
    €61–180

  6. Train via Milan

    1. Take the train from Roma Termini to Milan Rogoredotrain train 9962
    7h 6m
    €77–177

  7. Train via Genoa (Trenitalia)

    1. Take the train from Roma Termini to Genova P.Za Principetrain train Fa / ...
    2. Take the train from Genova P.Za Principe to Alessandriatrain train 2144 / ...
    7h 30m
    €63–167

  8. Fly to Genoa Cristoforo Colombo Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Genoa Cristoforo Colombo Airport (GOA)plane plane FCO - GOA
    2. Take the train from Genova P.Za Principe to Alessandriatrain train
    5h 52m
    €59–185

  9. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FCO - BLQ
    2. Take the train from Bologna centrale to Milano Centraletrain train
    3. Take the train from Milano Centrale to Paviatrain train
    4. Take the train from Pavia to Medetrain train
    6h 24m
    €78–207

Rome to Mede by bus

Calendar6Weekly Buses
Duration10h 14mAverage Duration
Ticket€50Cheapest Price
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Questions & Answers

Map of how to get from Rome to Mede.ExpandLaunch map view
  • Distance: 653.1 km
  • Duration: 5h 23m

What companies run services between Rome, Italy and Mede, Italy?

ItaloTreno operates a train from Roma Termini to Milano Centrale every 30 minutes. Tickets cost €70–150 and the journey takes 3h 5m. Alternatively, FlixBus operates a bus from Roma, Autostazione Tiburtina to Alessandria once daily. Tickets cost €50–85 and the journey takes 8h 30m.

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