There are 9 ways to get from Rome to Mede by train, bus, car, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Roma Termini to Milano Centraletrain 9950 / ...
5h 23m€75–124Fly to Turin Caselle Airport, train
cheapest- Fly from Fiumicino International Airport (FCO) to Turin Caselle Airport (TRN)plane FCO - TRN
- Take the train from Torino Lingotto to Alessandriatrain
6h 16m€36–224Bus
- Take the bus from Roma, Autostazione Tiburtina to Alessandriabus N503
10h 14m€45–75Drive 594.8 km
- Drive from Rome to Medecar 594.8 km
5h 40m€96–139Fly to Milan Linate Airport, train
- Fly from Fiumicino International Airport (FCO) to Milan Linate Airport (LIN)plane FCO - LIN
- Take the train from Pavia to Medetrain
5h 34m€66–198Train via Milan
- Take the train from Roma Termini to Milan Rogoredotrain 9962
6h 32m€72–123Train via Genoa (Trenitalia)
- Take the train from Roma Termini to Genova P.Za Principetrain Fa / ...
- Take the train from Genova P.Za Principe to Alessandriatrain 2144 / ...
7h 31m€63–137Fly to Genoa Cristoforo Colombo Airport, train
- Fly from Fiumicino International Airport (FCO) to Genoa Cristoforo Colombo Airport (GOA)plane FCO - GOA
- Take the train from Genova P.Za Principe to Alessandriatrain
- Take the train from Alessandria to Medetrain
5h 59m€55–188Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Fiumicino International Airport (FCO) to Bologna Guglielmo Marconi Airport (BLQ)plane FCO - BLQ
- Take the train from Bologna Centrale to Milano Rogoredotrain
- Take the train from Pavia to Medetrain
6h 13m€76–292
Rome to Mede by train
Comparing Your Travel Options
The cheapest way to get from Rome to Mede is to bus which costs €45 - €75 and takes 10h 14m.
The fastest way to get from Rome to Mede is to train which takes 5h 23m and costs €75 - €130.
No, there is no direct bus from Rome to Mede. However, there are services departing from Roma, Autostazione Tiburtina and arriving at Mede via Alessandria. The journey, including transfers, takes approximately 10h 14m.
No, there is no direct train from Rome to Mede. However, there are services departing from Roma Termini and arriving at Mede via Milano Centrale and Pavia. The journey, including transfers, takes approximately 5h 23m.
The distance between Rome and Mede is 653 km. The road distance is 594.8 km.
The best way to get from Rome to Mede without a car is to train which takes 5h 23m and costs €75 - €130.
It takes approximately 5h 23m to get from Rome to Mede, including transfers.
Rome to Mede bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Rome to Mede train services, operated by ItaloTreno, depart from Roma Termini station.
The best way to get from Rome to Mede is to train which takes 5h 23m and costs €75 - €130. Alternatively, you can bus, which costs €45 - €75 and takes 10h 14m.
What companies run services between Rome, Italy and Mede, Italy?
ItaloTreno operates a train from Roma Termini to Milano Centrale hourly. Tickets cost €65–110 and the journey takes 3h 5m. Alternatively, FlixBus operates a bus from Roma, Autostazione Tiburtina to Alessandria 5 times a week. Tickets cost €45–75 and the journey takes 8h 30m.
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Milan Linate Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €50–180
Flights from Fiumicino International Airport to Genoa Cristoforo Colombo Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- €50–160
Flights from Fiumicino International Airport to Turin Caselle Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €80–190
Flights from Fiumicino International Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 2m
- When
- Every day
- Estimated price
- €60–140
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 5m
- Frequency
- Hourly
- Estimated price
- €65–110
- Website
- Italo Treno
Train from Roma Termini to Milan Rogoredo
- Ave. Duration
- 4h 13m
- Frequency
- Once daily
- Estimated price
- €65–110
- Website
- Italo Treno
Train from Bologna Centrale to Milano Rogoredo
- Ave. Duration
- 1h 32m
- Frequency
- 3 times a day
- Estimated price
- €24–40
- Website
- Italo Treno
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Alessandria
- Ave. Duration
- 8h 30m
- Frequency
- 5 times a week
- Estimated price
- €45–75
- Website
- Flixbus
Want to know more about travelling around Italy
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Booking & Getting There
Rome to Mede bus services, operated by FlixBus, arrive at Alessandria station.
Rome to Mede train services, operated by ItaloTreno, arrive at Milano Centrale station.
Yes, the driving distance between Rome to Mede is 595 km. It takes approximately 5h 40m to drive from Rome to Mede.
Book your Rome to Mede train tickets online with Omio.
There are 314+ hotels available in Mede.









