Rome2Rio

How to get fromRome to Mainby plane, train (Trenitalia), bus, train, night train, car or car train

Find Transport to Main

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There are 6 ways to get from Rome to Main by plane, train (Trenitalia), bus, train, night train, car, or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Fiumicino International Airport (FCO) to Frankfurt (FRA)plane plane FCO - FRA
    4h 59m
    €51–210

  2. Train

    1. Take the train from Roma Termini to Milano Centraletrain train
    2. Take the train from Milano Centrale to Mannheim Hbftrain train Ec
    3. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    12h 32m
    €209–351

  3. Bus, train

    1. Take the bus from Roma, Autostazione Tiburtina to Mannheim central bus stationbus bus N77
    2. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    21h 19m
    €97–168

  4. Night train, train

    1. Take the night train from Roma Tiburtina to Muenchen Hbfnighttrain night train En
    2. Take the train from München Hbf to Frankfurttrain train 47 / ...
    19h 33m
    €245–454

  5. Drive 1,229.8 km

    1. Drive from Rome to Maincar car 1,229.8 km
    11h 32m
    €193–279

  6. Drive, car train

    1. Drive from Rome to Villach Hbfcar car
    2. Take the car train from Villach Hbf to Würzburg Hbfcartrain train
    3. Drive from Würzburg Hbf to Maincar car
    11h 57m
    €238–328

Rome to Main by bus and train

Calendar7Weekly Services
Duration21h 19mAverage Duration
Ticket€97Cheapest Price
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Questions & Answers

What companies run services between Rome, Italy and Main, Hesse, Germany?

easyJet, Condor Flugdienst, and three other airlines fly from Fiumicino International Airport (FCO) to Frankfurt (FRA) hourly. Alternatively, you can take a train from Roma Termini to Mainz, Römisches Theater via Milano Centrale, Mannheim Hbf, and Mannheim, Hauptbahnhof in around 12h 32m.

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Want to know more about travelling around Germany

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