There are 5 ways to get from Roma Termini to Mesagne by train (Trenitalia), bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Trenitalia)
best- Take the train from Roma Termini to BrindisiFr / ...
6h 35m€44–141Bus
cheapest- Take the bus from Roma, Autostazione Tiburtina to OstuniN573
9h 58m€14–85Drive 534.2 km
- Drive from Roma Termini to Mesagne534.2 km
6h 6m€84–122Fly, bus
- Fly from Fiumicino International Airport (FCO) to Brindisi Airport (BDS)FCO - BDS
- Take the bus from Brindisi Via N.Brandi to Mesagne
4h 20m€39–237Leonetti Bus
- Take the bus from Roma, Autostazione Tiburtina to Brindisi - Autorità PortualeRome
11h 22m€34–54
Roma Termini to Mesagne by bus
Questions & Answers
The cheapest way to get from Roma Termini to Mesagne is to bus which costs €13 - €85 and takes 9h 58m.
The fastest way to get from Roma Termini to Mesagne is to fly and bus which takes 4h 20m and costs €35 - €240.
No, there is no direct bus from Roma Termini to Mesagne. However, there are services departing from P.Za Di Cinquecento and arriving at Mesagne via Roma, Autostazione Tiburtina and Ostuni - viale Dello Sport. The journey, including transfers, takes approximately 9h 58m.
The distance between Roma Termini and Mesagne is 606 km. The road distance is 534.2 km.
The best way to get from Roma Termini to Mesagne without a car is to train which takes 6h 35m and costs €40 - €150.
It takes approximately 6h 35m to get from Roma Termini to Mesagne, including transfers.
Roma Termini to Mesagne bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
The best way to get from Roma Termini to Mesagne is to train which takes 6h 35m and costs €40 - €150. Alternatively, you can bus, which costs €13 - €85 and takes 9h 58m.
Roma Termini to Mesagne bus services, operated by FlixBus, arrive at Ostuni station.
Yes, the driving distance between Roma Termini to Mesagne is 534 km. It takes approximately 6h 6m to drive from Roma Termini to Mesagne.
What companies run services between Roma Termini, Italy and Mesagne, Italy?
Trenitalia Frecce operates a train from Roma Termini to Brindisi 5 times a day. Tickets cost €40–140 and the journey takes 5h 17m. Alternatively, FlixBus operates a bus from Roma, Autostazione Tiburtina to Ostuni once daily. Tickets cost €17–75 and the journey takes 6h 55m. Itabus S.p.A. also services this route once daily.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- ryanair.com
Flights from Fiumicino International Airport to Brindisi Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €30–180
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Brindisi Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €45–210
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Brindisi
- Ave. Duration
- 5h 17m
- Frequency
- 5 times a day
- Estimated price
- €40–140
- Schedules at
- trenitalia.com
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Roma, Autostazione Tiburtina to Ostuni
- Ave. Duration
- 6h 55m
- Frequency
- Once daily
- Estimated price
- €17–75
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Roma, Autostazione Tiburtina to Ostuni
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- €11–70
- Website
- https://www.itabus.it/en/home
- Phone
- 800232042, 3667880781
- Website
- stpbrindisi.it
Bus from Brindisi Via N.Brandi to Mesagne
- Ave. Duration
- 27 min
- Frequency
- Hourly
- Estimated price
- €1
- Schedules at
- stpbrindisi.it
- Phone
- +39081/969167
- servizioclienti@leonettiroma.it
- Website
- leonettiroma.it
Bus from Roma, Autostazione Tiburtina to Brindisi - Autorità Portuale
- Ave. Duration
- 8h 30m
- Frequency
- Once a week
- Estimated price
- €30–50
- Website
- https://www.leonettiroma.it/
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