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How to get fromRoma Termini to Mesagneby train (Trenitalia), bus, car or plane

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There are 5 ways to get from Roma Termini to Mesagne by train (Trenitalia), bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from Roma Termini to BrindisitrainFr / ...
    6h 35m
    €44–141
  2. Bus

    cheapest
    1. Take the bus from Roma, Autostazione Tiburtina to OstunibusN573
    9h 58m
    €14–85
  3. Drive 534.2 km

    1. Drive from Roma Termini to Mesagnecar534.2 km
    6h 6m
    €84–122
  4. Fly, bus

    1. Fly from Fiumicino International Airport (FCO) to Brindisi Airport (BDS)planeFCO - BDS
    2. Take the bus from Brindisi Via N.Brandi to Mesagnebus
    4h 20m
    €39–237
  5. Leonetti Bus

    1. Take the bus from Roma, Autostazione Tiburtina to Brindisi - Autorità PortualebusRome
    11h 22m
    €34–54

Roma Termini to Mesagne by bus

Calendar12Weekly Buses
Duration9h 58mAverage Duration
Ticket€14Cheapest Price
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Questions & Answers

What companies run services between Roma Termini, Italy and Mesagne, Italy?

Trenitalia Frecce operates a train from Roma Termini to Brindisi 5 times a day. Tickets cost €40–140 and the journey takes 5h 17m. Alternatively, FlixBus operates a bus from Roma, Autostazione Tiburtina to Ostuni once daily. Tickets cost €17–75 and the journey takes 6h 55m. Itabus S.p.A. also services this route once daily.

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