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How to get fromRoma Termini to Mendrisioby train (Trenitalia), bus, car, plane or train

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There are 7 ways to get from Roma Termini to Mendrisio by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Roma Termini to Milano CentraletrainFr / ...
    2. Take the train from Milano Centrale to MendrisiotrainRe80
    4h 26m
    CHF 41–111
  2. Bus

    cheapest
    1. Take the bus from Roma, Autostazione Tiburtina to Comobus518 / ...
    11h 49m
    CHF 34–136
  3. Drive 627.5 km

    1. Drive from Roma Termini to Mendrisiocar627.5 km
    5h 59m
    CHF 102–148
  4. Fly to Milano Malpensa Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Milano Malpensa Airport (MXP)planeFCO - MXP
    2. Take the train from Malpensa Aeroporto T1 to Mendrisiotrain
    4h 14m
    CHF 48–179
  5. Train via Milan

    1. Take the train from Roma Termini to Milan Rogoredotrain9984 / ...
    2. Take the train from Milano Centrale to MendrisiotrainRe80
    4h 37m
    CHF 50–124
  6. Fly to Milan Linate Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Milan Linate Airport (LIN)planeFCO - LIN
    2. Take the train from Monza to Mendrisiotrain
    4h 58m
    CHF 49–212
  7. Fly to Turin Caselle Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Turin Caselle Airport (TRN)planeFCO - TRN
    2. Take the train from Torino Porta Susa to Milano Centraletrain
    3. Take the train from Milano Centrale to Mendrisiotrain
    5h 56m
    CHF 58–259

Roma Termini to Mendrisio by train

Calendar246Weekly Trains
Duration4h 26mAverage Duration
TicketCHF 41Cheapest Price
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Questions & Answers

What companies run services between Roma Termini, Italy and Mendrisio, Switzerland?

You can take a train from Roma Termini to Mendrisio via Milano Centrale in around 4h 26m. Alternatively, FlixBus operates a bus from Roma, Autostazione Tiburtina to Como twice daily. Tickets cost CHF 30–70 and the journey takes 9h 35m. Marino Autolinee S.p.A. also services this route once daily.

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