There are 6 ways to get from Roma Termini to Mainz by plane, train (Trenitalia), bus, car, or car train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Fiumicino International Airport (FCO) to Frankfurt (FRA)FCO - FRA
4h 53m€54–208Train
- Take the train from Roma Termini to Milano CentraleFr / ...
- Take the train from Milano Centrale to Mannheim HbfEc
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches TheaterS6
12h 36m€173–302Bus via Pescara
- Take the bus from Roma Termini Giolitti to Pescara
- Take the bus from Pescara to Frankfurt
19h 51m€107–133Drive 1,231.4 km
- Drive from Roma Termini to Mainz1,231.4 km
11h 25m€192–277Bus
- Take the bus from Roma, Autostazione Tiburtina to Frankfurt central train stationN77
22h 53m€70–156Drive, car train
- Drive from Roma Termini to Villach Hbf
- Take the car train from Villach Hbf to Würzburg Hbf
- Drive from Würzburg Hbf to Mainz
12h 11m€235–323
Roma Termini to Mainz by train
Questions & Answers
The cheapest way to get from Roma Termini to Mainz is to fly which costs €50 - €210 and takes 4h 53m.
The fastest way to get from Roma Termini to Mainz is to fly which takes 4h 53m and costs €50 - €210.
No, there is no direct bus from Roma Termini to Mainz station. However, there are services departing from Roma Termini Giolitti and arriving at Mainz central train station via Pescara and Frankfurt central train station. The journey, including transfers, takes approximately 19h 51m.
No, there is no direct train from Roma Termini to Mainz. However, there are services departing from Roma Termini and arriving at Mainz, Römisches Theater via Milano Centrale and Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 12h 36m.
The distance between Roma Termini and Mainz is 1019 km. The road distance is 1231.4 km.
The best way to get from Roma Termini to Mainz without a car is to train which takes 12h 36m and costs €170 - €310.
It takes approximately 4h 53m to get from Roma Termini to Mainz, including transfers.
Roma Termini to Mainz bus services, operated by Di Fonzo, depart from Roma Termini Giolitti station.
Roma Termini to Mainz train services, operated by Trenitalia Frecce, depart from Roma Termini station.
The best way to get from Roma Termini to Mainz is to fly which takes 4h 53m and costs €50 - €210. Alternatively, you can train, which costs €170 - €310 and takes 12h 36m, you could also bus via Pescara, which costs €100 - €140 and takes 19h 51m.
What companies run services between Roma Termini, Italy and Mainz, Germany?
ITA Airways, easyJet, and three other airlines fly from Fiumicino International Airport (FCO) to Frankfurt (FRA) every 3 hours. Alternatively, you can take a train from Roma Termini to Mainz, Römisches Theater via Milano Centrale, Mannheim Hbf, and Mannheim, Hauptbahnhof in around 12h 36m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Frankfurt
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- €60–250
Flights from Fiumicino International Airport to Frankfurt via Milan Linate
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- €90–290
- Website
- lufthansa.com
Flights from Fiumicino International Airport to Frankfurt
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- €60–250
Flights from Fiumicino International Airport to Frankfurt via Milan Linate
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- €90–290
- Website
- easyjet.com
Flights from Fiumicino International Airport to Frankfurt
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €40–140
- Website
- condor.com
Flights from Fiumicino International Airport to Frankfurt
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €50–190
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 8m
- Frequency
- Every 30 minutes
- Estimated price
- €50–110
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 40m
- Frequency
- Hourly
- Estimated price
- €45–100
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 7h 25m
- Frequency
- Once a week
- Estimated price
- €40–75
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Milano Centrale to Mannheim Hbf
- Ave. Duration
- 6h 48m
- Frequency
- Once daily
- Estimated price
- €120–180
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €120–180
- 2nd Class
- €120–160
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 19m
- Frequency
- Hourly
- Estimated price
- €13–19
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 5 times a week
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +49 (0) 221 800 20 820
- info@urlaubs-express.de
- Website
- urlaubs-express.de
Car train from Villach Hbf to Würzburg Hbf
- Ave. Duration
- 3h 34m
- Frequency
- Once daily
- Estimated price
- €95–120
- Website
- https://urlaubs-express.de/?lang=en
- Phone
- +39 0873 364785
- info@difonzobus.com
- Website
- difonzobus.com
Bus from Roma Termini Giolitti to Pescara
- Ave. Duration
- 2h 10m
- Frequency
- Every 4 hours
- Estimated price
- €12–15
- Schedules at
- difonzobus.com
- Phone
- +39 098 3520 315
- info@fsbusitaliafast.it
- Website
- simetbus.it
Bus from Pescara to Frankfurt
- Ave. Duration
- 14h 50m
- Frequency
- Once a week
- Estimated price
- €90–110
- Schedules at
- simetbus.it
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Roma, Autostazione Tiburtina to Frankfurt central train station
- Ave. Duration
- 20h 55m
- Frequency
- Once daily
- Estimated price
- €60–140
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Germany
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
More Questions & Answers
Roma Termini to Mainz bus services, operated by Di Fonzo, arrive at Pescara station.
Roma Termini to Mainz train services, operated by Trenitalia Frecce, arrive at Milano Centrale station.
Yes, the driving distance between Roma Termini to Mainz is 1231 km. It takes approximately 11h 25m to drive from Roma Termini to Mainz.
Book your Roma Termini to Mainz train tickets online with Omio.
There are 1132+ hotels available in Mainz.







































