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How to get fromRochester to Pittsburghby bus (Greyhound), train (Amtrak), car, plane, bus, or bus (Flixbus, Greyhound)

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There are 6 ways to get from Rochester to Pittsburgh by bus (Greyhound), train (Amtrak), car, plane, bus, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Brook Park (Greyhound)

    best
    1. Take the bus from Rochester Bus Stop to Cleveland Bus Stationbus bus Greyhound US0171
    2. Take the bus from Cleveland Bus Station to Pittsburgh Intermodal Stationbus bus Greyhound US0420 / ...
    8h 10m
    $75–115

  2. Drive  282.9 mi

    cheapest
    1. Drive from Rochester to Pittsburghcar car 282.9 mi
    4h 56m
    $49–70

  3. Train (Amtrak)

    1. Take the train from Rochester to Cleveland Amtraktrain train Lake Shore Limited
    2. Take the train from Cleveland Amtrak to Pittsburgh Amtrak Stationtrain train Floridian
    8h 35m
    $212–330

  4. Fly

    1. Fly from Rochester (ROC) to Pittsburgh International Airport (PIT)plane plane ROC - PIT
    5h 3m
    $127–720

  5. Bus

    1. Take the bus from Rochester to Buffalobus bus Adt N810-D / ...
    2. Take the bus from Buffalo to Pittsburghbus bus Fab530
    9h 50m
    $89–295

  6. Bus #2

    1. Take the bus from Rochester Bus Stop to Buffalobus bus FlixBus 2685 / ...
    2. Take the bus from Buffalo to Pittsburghbus bus Fab530
    10h
    $82–270

Rochester to Pittsburgh by bus (Greyhound)

Calendar14Weekly Buses
Duration8h 10mAverage Duration
Ticket$75Cheapest Price
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Comparing Your Travel Options

Map of how to get from Rochester to Pittsburgh.ExpandLaunch map view
  • Distance: 407.4 mi
  • Duration: 8h 10m

What companies run services between Rochester, NY, USA and Pittsburgh, PA, USA?

You can take a bus from Rochester Bus Stop to Pittsburgh Intermodal Station via Cleveland Bus Station in around 8h 10m. Alternatively, you can take a train from Rochester to Pittsburgh Amtrak Station via Cleveland Amtrak in around 8h 35m.

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