There are 6 ways to get from Rochester to Natick by plane, train, bus (Greyhound), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Rochester, train
best- Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane ROC - BOS
- Take the train from Back Bay to Natick Centertrain
3h 22m$259–788Bus, train
cheapest- Take the bus from Rochester to Syracusebus 325
- Take the bus from Syracuse Bus Station to Albanybus
- Take the bus from Albany to Worcester Union Stationbus
- Take the train from Worcester to Natick Centertrain
11h 28m$60–127Bus (Greyhound)
- Take the bus from Rochester Bus Stop to Bostonbus Greyhound US0171
10h 25m$66–129Train (Amtrak)
- Take the train from Rochester to Framingham Amtraktrain Lake Shore Limited
10h 42m$111–248Drive 375.7 mi
- Drive from Rochester to Natickcar 375.7 mi
6h 34m$69–99Bus to Buffalo Niagara International Airport, fly
- Take the bus from Rochester Bus Stop to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane BUF - BOS
5h 20m$110–632
Rochester to Natick by bus (Greyhound)
Questions & Answers
The cheapest way to get from Rochester to Natick is to bus which costs $65 - $130 and takes 10h 25m.
The fastest way to get from Rochester to Natick is to fly and train which takes 3h 22m and costs $250 - $800.
No, there is no direct bus from Rochester to Natick. However, there are services departing from Rochester Bus Stop and arriving at Natick Center - South Ave opp Adams St via South Station - Bus Terminal Gate B1/B2. The journey, including transfers, takes approximately 10h 25m.
No, there is no direct train from Rochester to Natick. However, there are services departing from Rochester and arriving at Natick Center via Framingham. The journey, including transfers, takes approximately 10h 42m.
The distance between Rochester and Natick is 375 miles. The road distance is 377.9 miles.
The best way to get from Rochester to Natick without a car is to bus which takes 10h 25m and costs $65 - $130.
It takes approximately 3h 22m to get from Rochester to Natick, including transfers.
Rochester to Natick bus services, operated by Greyhound USA, depart from Rochester Bus Stop station.
Rochester to Natick train services, operated by Amtrak, depart from Rochester station.
The best way to get from Rochester to Natick is to bus which takes 10h 25m and costs $65 - $130. Alternatively, you can train, which costs $110 - $250 and takes 10h 42m.
What companies run services between Rochester, NY, USA and Natick, MA, USA?
Greyhound USA operates a bus from Rochester Bus Stop to Boston once daily. Tickets cost $65–130 and the journey takes 8h 40m. Alternatively, Amtrak operates a train from Rochester to Framingham Amtrak once daily. Tickets cost $110–250 and the journey takes 9h 52m.
- Website
- aa.com
Flights from Rochester to Boston Logan Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $65–450
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $90–600
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $90–600
- Website
- united.com
Flights from Rochester to Boston Logan Airport via Newark
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- $75–480
- Website
- southwest.com
Flights from Rochester to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 42m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–550
- Website
- delta.com
Flights from Rochester to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 3h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–480
- Phone
- +1-617-222-3200
- Website
- mbta.com
Train from Back Bay to Natick Center
- Ave. Duration
- 34 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- https://www.mbta.com
- Adult
- $3–9
Train from Worcester to Natick Center
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $5–11
- Website
- https://www.mbta.com
- Adult
- $5–11
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Rochester to Framingham Amtrak
- Ave. Duration
- 9h 52m
- Frequency
- Once daily
- Estimated price
- $110–250
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Rochester Bus Stop to Boston
- Ave. Duration
- 8h 40m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Rochester Bus Stop to Buffalo Niagara International Airport
- Ave. Duration
- 1h 10m
- Frequency
- Every 3 hours
- Estimated price
- $8–14
- Schedules at
- flixbus.com
Bus from Syracuse Bus Station to Albany
- Ave. Duration
- 2h 45m
- Frequency
- 5 times a week
- Estimated price
- $18–35
- Schedules at
- flixbus.com
Bus from Albany to Worcester Union Station
- Ave. Duration
- 3h 30m
- Frequency
- 5 times a week
- Estimated price
- $17–30
- Schedules at
- flixbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Rochester to Syracuse
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $20–55
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $20–50
- Flexible
- $40–55
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More Questions & Answers
Rochester to Natick bus services, operated by Greyhound USA, arrive at Boston station.
Rochester to Natick train services, operated by Amtrak, arrive at Framingham Amtrak station.
Yes, the driving distance between Rochester to Natick is 378 miles. It takes approximately 6h 34m to drive from Rochester to Natick.
There are 437+ hotels available in Natick.













