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How to get fromRochester to Natickby plane, train, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

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There are 6 ways to get from Rochester to Natick by plane, train, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Rochester, train

    best
    1. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    2. Take the train from Back Bay to Natick Centertrain train
    3h 24m
    $89–438

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Rochester Bus Stop to Springfield Union Stationbus bus Greyhound US0171
    2. Take the bus from Springfield Union Station to Framinghambus bus Greyhound US0270s
    10h 38m
    $54–102

  3. Train (Amtrak)

    1. Take the train from Rochester to Framingham Amtraktrain train Lake Shore Limited
    10h 42m
    $111–248

  4. Drive 375.7 mi

    1. Drive from Rochester to Natickcar car 375.7 mi
    6h 34m
    $69–99

  5. Bus to Buffalo Niagara International Airport, fly

    1. Take the bus from Rochester Bus Stop to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    5h 25m
    $76–402

  6. Bus via Ithaca (Flixbus)

    1. Take the bus from Rochester Bus Stop to Ithacabus bus FlixBus 2685 / ...
    2. Take the bus from Ithaca to Bostonbus bus FlixBus 2691
    12h 29m
    $65–114

Rochester to Natick by bus (Greyhound)

Calendar7Weekly Buses
Duration10h 38mAverage Duration
Ticket$54Cheapest Price
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Questions & Answers

Map of how to get from Rochester to Natick.ExpandLaunch map view
  • Distance: 372.7 mi
  • Duration: 3h 24m

What companies run services between Rochester, NY, USA and Natick, MA, USA?

You can take a bus from Rochester Bus Stop to Natick Center MBTA via Springfield Union Station, Framingham, and Framingham MBTA Station in around 10h 38m. Alternatively, Amtrak operates a train from Rochester to Framingham Amtrak once daily. Tickets cost $110–250 and the journey takes 9h 52m.

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Need to know: Greyhound

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