There are 6 ways to get from Rochester to Milwaukee by plane, train (Amtrak), bus (Flixbus, Greyhound), car, bus, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Rochester
best- Fly from Rochester (ROC) to General Mitchell International Airport (MKE)ROC - MKE
4h 33m$180–973Bus
cheapest- Take the bus from Rochester Bus Stop to Buffalo
- Take the bus from Buffalo to Cleveland Bus Station
- Take the bus from Cleveland Bus Station to Chicago Bus Station
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Station
17h 20m$91–237Train (Amtrak)
- Take the train from Rochester to Chicago Union StationLake Shore Limited
- Take the train from Chicago Union Station to MilwaukeeHiawatha Service / ...
14h 12m$100–242Drive 687.4 mi
- Drive from Rochester to Milwaukee687.4 mi
11h 47m$126–182Bus to Buffalo Niagara International Airport, fly
- Take the bus from Rochester Bus Stop to Buffalo Niagara International Airport
- Fly from Buffalo Niagara International Airport (BUF) to General Mitchell International Airport (MKE)BUF - MKE
6h 26m$208–1,224Bus via Detroit
- Take the bus from Rochester to Toronto
- Take the bus from Toronto to Detroit Bus Station
- Take the bus from Detroit Bus Station to Milwaukee Intermodal Station
21h 25m$116–304
Rochester to Milwaukee by train (Amtrak)
Questions & Answers
The cheapest way to get from Rochester to Milwaukee is to drive which costs $120 - $190 and takes 11h 47m.
The fastest way to get from Rochester to Milwaukee is to fly which takes 4h 33m and costs $180 - $1,000.
No, there is no direct bus from Rochester to Milwaukee station. However, there are services departing from Rochester Bus Stop and arriving at Milwaukee Intermodal Station via Buffalo, Cleveland Bus Station and Chicago Bus Station. The journey, including transfers, takes approximately 17h 20m.
No, there is no direct train from Rochester to Milwaukee. However, there are services departing from Rochester and arriving at Milwaukee via Chicago Union Station. The journey, including transfers, takes approximately 14h 12m.
The distance between Rochester and Milwaukee is 531 miles. The road distance is 691.4 miles.
The best way to get from Rochester to Milwaukee without a car is to train which takes 14h 12m and costs $95 - $250.
It takes approximately 4h 33m to get from Rochester to Milwaukee, including transfers.
Rochester to Milwaukee bus services, operated by Flixbus USA, depart from Rochester Bus Stop station.
Rochester to Milwaukee train services, operated by Amtrak, depart from Rochester station.
The best way to get from Rochester to Milwaukee is to fly which takes 4h 33m and costs $180 - $1,000. Alternatively, you can train, which costs $95 - $250 and takes 14h 12m, you could also bus, which costs $90 - $240 and takes 17h 20m.
What companies run services between Rochester, NY, USA and Milwaukee, WI, USA?
Delta, Southwest Airlines, and two other airlines fly from Rochester (ROC) to General Mitchell International Airport (MKE) hourly. Alternatively, you can take a train from Rochester to Milwaukee via Chicago Union Station in around 14h 12m.
- Website
- aa.com
Flights from Rochester to General Mitchell International Airport via Chicago O'Hare
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $170–1,000
Flights from Rochester to General Mitchell International Airport via Reagan Washington
- Ave. Duration
- 6h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $220–1,200
Flights from Rochester to General Mitchell International Airport via Philadelphia
- Ave. Duration
- 5h 6m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $220–1,200
Flights from Buffalo Niagara International Airport to General Mitchell International Airport via Chicago O'Hare
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $200–1,200
Flights from Buffalo Niagara International Airport to General Mitchell International Airport via Reagan Washington
- Ave. Duration
- 6h 19m
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $270–1,400
Flights from Buffalo Niagara International Airport to General Mitchell International Airport via Philadelphia
- Ave. Duration
- 5h 58m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $280–1,500
- Website
- delta.com
Flights from Rochester to General Mitchell International Airport via Detroit
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $160–950
Flights from Rochester to General Mitchell International Airport via New York La Guardia
- Ave. Duration
- 5h 52m
- When
- Monday to Friday
- Estimated price
- $230–1,200
Flights from Buffalo Niagara International Airport to General Mitchell International Airport via Detroit
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $190–1,200
- Website
- southwest.com
Flights from Rochester to General Mitchell International Airport via Baltimore
- Ave. Duration
- 4h 25m
- When
- Monday, Friday, and Saturday
- Estimated price
- $220–1,200
Flights from Rochester to General Mitchell International Airport via Chicago Midway
- Ave. Duration
- 6h 30m
- When
- Monday and Friday
- Estimated price
- $170–1,000
Flights from Buffalo Niagara International Airport to General Mitchell International Airport via Baltimore
- Ave. Duration
- 5h 11m
- When
- Wednesday, Thursday, and Saturday
- Estimated price
- $270–1,400
Flights from Buffalo Niagara International Airport to General Mitchell International Airport via Nashville
- Ave. Duration
- 5h 5m
- When
- Monday, Tuesday, and Friday
- Estimated price
- $310–1,600
Flights from Buffalo Niagara International Airport to General Mitchell International Airport via Chicago Midway
- Ave. Duration
- 6h 25m
- When
- Monday, Thursday, and Friday
- Estimated price
- $200–1,200
- Website
- united.com
Flights from Rochester to General Mitchell International Airport via Chicago O'Hare
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $170–1,000
Flights from Buffalo Niagara International Airport to General Mitchell International Airport via Chicago O'Hare
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $200–1,200
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Rochester to Chicago Union Station
- Ave. Duration
- 11h 43m
- Frequency
- Twice daily
- Estimated price
- $75–210
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $22–40
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $15–22
- Schedules at
- flixbus.com
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $19–35
- Schedules at
- flixbus.com
Bus from Rochester Bus Stop to Buffalo Niagara International Airport
- Ave. Duration
- 1h 10m
- Frequency
- Every 4 hours
- Estimated price
- $15–22
- Schedules at
- flixbus.com
Bus from Toronto to Detroit Bus Station
- Ave. Duration
- 6h 50m
- Frequency
- 3 times a day
- Estimated price
- $35–85
- Schedules at
- flixbus.com
Bus from Detroit Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 7h 55m
- Frequency
- 4 times a week
- Estimated price
- $50–110
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 25m
- Frequency
- 4 times a day
- Estimated price
- $16–23
- Website
- https://www.greyhound.com/
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $27–60
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Twice daily
- Estimated price
- $40–90
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $19–65
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 35m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://baronsbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Rochester to Toronto
- Ave. Duration
- 4h 40m
- Frequency
- Twice daily
- Estimated price
- $30–110
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $30–110
- Flexible
- $55–110
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Rochester to Milwaukee bus services, operated by Flixbus USA, arrive at Buffalo station.
Milwaukee is 1h behind Rochester. It is currently 3:18 PM in Rochester and 2:18 PM in Milwaukee.
Rochester to Milwaukee train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Rochester to Milwaukee is 691 miles. It takes approximately 11h 47m to drive from Rochester to Milwaukee.
Book your Rochester to Milwaukee train tickets online with Omio.
Book your Rochester to Milwaukee bus tickets online with Omio and FlixBus.
There are 262+ hotels available in Milwaukee.













