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How to get fromRochester to Indianapolisby plane, train, bus, bus (Flixbus, Greyhound), car or train (Amtrak)

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There are 7 ways to get from Rochester to Indianapolis by plane, train, bus, bus (Flixbus, Greyhound), car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Rochester

    best
    1. Fly from Rochester (ROC) to Indianapolis (IND)plane plane ROC - IND
    5h 1m
    $199–622

  2. Train, bus

    cheapest
    1. Take the train from Rochester to Toledotrain train Lake Shore Limited
    2. Take the bus from Toledo to Indianapolis, INbus bus Detroit
    11h 49m
    $52–220

  3. Bus

    1. Take the bus from Rochester Bus Stop to Buffalobus bus
    2. Take the bus from Buffalo, NY to Cincinnati, OHbus bus
    3. Take the bus from Cincinnati Bus Station to Indianapolis Union Stationbus bus
    15h 30m
    $80–153

  4. Drive 563.5 mi

    1. Drive from Rochester to Indianapoliscar car 563.5 mi
    9h 41m
    $103–149

  5. Bus to Buffalo Niagara International Airport, fly

    1. Take the bus from Rochester Bus Stop to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Indianapolis (IND)plane plane BUF - IND
    7h 1m
    $127–674

  6. Bus via Cleveland

    1. Take the bus from Rochester Bus Stop to Buffalobus bus
    2. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Dayton Trotwood Bus Stationbus bus
    4. Take the bus from Dayton Trotwood Bus Station to Indianapolisbus bus
    15h 30m
    $96–243

  7. Train (Amtrak)

    1. Take the train from Rochester to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    17h 37m
    $96–265

Rochester to Indianapolis by train and bus

Calendar7Weekly Services
Duration11h 49mAverage Duration
Ticket$52Cheapest Price
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Questions & Answers

What companies run services between Rochester, NY, USA and Indianapolis, IN, USA?

Delta, United Airlines, and two other airlines fly from Rochester (ROC) to Indianapolis (IND) hourly. Alternatively, you can take a bus from Rochester Bus Stop to Indianapolis Union Station via Buffalo, Buffalo, NY, Cincinnati, OH, and Cincinnati Bus Station in around 15h 30m.

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