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How to get fromRochester to Indianapolisby plane, train, bus, bus (Flixbus, Greyhound), car, bus (Greyhound), or train (Amtrak)

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There are 7 ways to get from Rochester to Indianapolis by plane, train, bus, bus (Flixbus, Greyhound), car, bus (Greyhound), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Rochester

    best
    1. Fly from Rochester (ROC) to Indianapolis (IND)plane plane ROC - IND
    4h 47m
    $139–722

  2. Bus

    cheapest
    1. Take the bus from Rochester Bus Stop to Buffalobus bus
    2. Take the bus from Buffalo to Columbusbus bus
    3. Take the bus from Columbus to Indianapolisbus bus
    13h 25m
    $82–133

  3. Train, bus

    1. Take the train from Rochester to Toledotrain train Lake Shore Limited
    2. Take the bus from Toledo to Indianapolis, INbus bus Detroit / ...
    11h 49m
    $112–266

  4. Drive  563.5 mi

    1. Drive from Rochester to Indianapoliscar car 563.5 mi
    9h 46m
    $103–149

  5. Bus to Buffalo Niagara International Airport, fly

    1. Take the bus from Rochester Bus Stop to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Indianapolis (IND)plane plane BUF - IND
    6h 36m
    $102–566

  6. Bus via Brook Park (Greyhound)

    1. Take the bus from Rochester Bus Stop to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Dayton Trotwood Bus Stationbus bus
    3. Take the bus from Dayton Trotwood Bus Station to Indianapolis Union Stationbus bus
    14h 15m
    $89–148

  7. Train (Amtrak)

    1. Take the train from Rochester to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    17h 37m
    $201–453

Rochester to Indianapolis by train and bus

Calendar14Weekly Services
Duration11h 49mAverage Duration
Ticket$112Cheapest Price
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Comparing Your Travel Options

Map of how to get from Rochester to Indianapolis.ExpandLaunch map view
  • Distance: 524.2 mi
  • Duration: 4h 47m

What companies run services between Rochester, NY, USA and Indianapolis, IN, USA?

Delta, Southwest Airlines, and two other airlines fly from Rochester (ROC) to Indianapolis (IND) hourly. Alternatively, you can take a bus from Rochester Bus Stop to Indianapolis via Buffalo and Columbus in around 13h 25m.

Airlines
Train operators
Bus operators

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