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How to get fromRochester to Chicagoby plane, train (Amtrak), bus (Flixbus, Greyhound), car or bus

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There are 7 ways to get from Rochester to Chicago by plane, train (Amtrak), bus (Flixbus, Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to Chicago O'Hare International Airport

    best
    1. Fly from Rochester (ROC) to Chicago O'Hare International Airport (ORD)plane plane ROC - ORD
    3h 16m
    $149–515

  2. Train (Amtrak)

    cheapest
    1. Take the train from Rochester to Chicago Union Stationtrain train Lake Shore Limited
    11h 43m
    $65–200

  3. Bus

    1. Take the bus from Rochester Bus Stop to Buffalobus bus
    2. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus
    14h 25m
    $71–158

  4. Drive 599.5 mi

    1. Drive from Rochester to Chicagocar car 599.5 mi
    10h 11m
    $110–158

  5. Fly Rochester to Chicago Midway International Airport

    1. Fly from Rochester (ROC) to Chicago Midway International Airport (MDW)plane plane ROC - MDW
    3h 4m
    $109–575

  6. Bus to Buffalo Niagara International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Rochester Bus Stop to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane plane BUF - ORD
    5h 2m
    $93–487

  7. Bus to Buffalo Niagara International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Rochester Bus Stop to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane plane BUF - MDW
    4h 51m
    $128–727

Rochester to Chicago by train (Amtrak)

Calendar14Weekly Trains
Duration11h 43mAverage Duration
Ticket$65Cheapest Price
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Questions & Answers

What companies run services between Rochester, NY, USA and Chicago, IL, USA?

American Airlines, United Airlines, and Delta fly from Rochester (ROC) to Chicago O'Hare International Airport (ORD) every 2 hours. Alternatively, Amtrak operates a train from Rochester to Chicago Union Station twice daily. Tickets cost $65–200 and the journey takes 11h 43m.

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