There are 6 ways to get from Rochester to Brookline by plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Rochester
best- Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane ROC - BOS
2h 10m$101–529Bus (Greyhound)
cheapest- Take the bus from Rochester Bus Stop to Bostonbus Greyhound US0171
9h 11m$66–105Train (Amtrak)
- Take the train from Rochester to Bostontrain Lake Shore Limited
10h 18m$230–370Drive 387.3 mi
- Drive from Rochester to Brooklinecar 387.3 mi
6h 52m$71–103Bus to Buffalo Niagara International Airport, fly
- Take the bus from Rochester Bus Stop to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane BUF - BOS
4h 9m$79–393Bus via Ithaca (Flixbus)
- Take the bus from Rochester Bus Stop to Ithacabus FlixBus 2685 / ...
- Take the bus from Ithaca to Bostonbus FlixBus 2691
11h 39m$71–108
Rochester to Brookline by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Rochester to Brookline is to bus which costs $65 - $110 and takes 9h 11m.
The fastest way to get from Rochester to Brookline is to fly which takes 2h 10m and costs $100 - $550.
No, there is no direct bus from Rochester to Brookline. However, there are services departing from Rochester Bus Stop and arriving at Nubian via Essex St @ Atlantic Ave. The journey, including transfers, takes approximately 9h 11m.
Yes, there is a direct train departing from Rochester and arriving at Boston. Services depart once daily, and operate every day. The journey takes approximately 10h 18m.
The distance between Rochester and Brookline is 358 miles. The road distance is 389.5 miles.
The best way to get from Rochester to Brookline without a car is to bus which takes 9h 11m and costs $65 - $110.
It takes approximately 2h 10m to get from Rochester to Brookline, including transfers.
Rochester to Brookline bus services, operated by Greyhound USA, depart from Rochester Bus Stop station.
Rochester to Brookline train services, operated by Amtrak, depart from Rochester station.
The best way to get from Rochester to Brookline is to fly which takes 2h 10m and costs $100 - $550. Alternatively, you can bus, which costs $65 - $110 and takes 9h 11m, you could also train, which costs $230 - $370 and takes 10h 18m.
What companies run services between Rochester, NY, USA and Brookline, MA, USA?
American Airlines, Southwest Airlines, and two other airlines fly from Rochester (ROC) to Boston Logan Airport (BOS) every 4 hours. Alternatively, Greyhound USA operates a bus from Rochester Bus Stop to Boston once daily. Tickets cost $65–100 and the journey takes 8h 40m.
- Website
- aa.com
Flights from Rochester to Boston Logan Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $75–500
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $60–370
- Website
- southwest.com
Flights from Rochester to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 47m
- When
- Sunday and Saturday
- Estimated price
- $100–600
Flights from Buffalo Niagara International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 41m
- When
- Monday to Wednesday
- Estimated price
- $75–430
- Website
- jetblue.com
Flights from Rochester to Boston Logan Airport via New York JFK
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- $85–550
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $60–370
- Website
- united.com
Flights from Rochester to Boston Logan Airport via Newark
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $85–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Rochester to Boston
- Ave. Duration
- 10h 18m
- Frequency
- Once daily
- Estimated price
- $230–370
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Rochester Bus Stop to Boston
- Ave. Duration
- 8h 40m
- Frequency
- Once daily
- Estimated price
- $65–100
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo Niagara International Airport
- Ave. Duration
- 1h 10m
- Frequency
- Every 4 hours
- Estimated price
- $9–15
- Schedules at
- Flixbus USA
Bus from Rochester Bus Stop to Ithaca
- Ave. Duration
- 2h 10m
- Frequency
- Twice daily
- Estimated price
- $13–20
- Schedules at
- Flixbus USA
Bus from Ithaca to Boston
- Ave. Duration
- 7h 55m
- Frequency
- 3 times a week
- Estimated price
- $55–85
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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Booking & Getting There
Rochester to Brookline bus services, operated by Greyhound USA, arrive at Boston station.
Rochester to Brookline train services, operated by Amtrak, arrive at Boston station.
Yes, the driving distance between Rochester to Brookline is 390 miles. It takes approximately 6h 52m to drive from Rochester to Brookline.
Book your Rochester to Brookline train tickets online with Omio.
Book your Rochester to Brookline bus tickets online with Omio.
There are 1696+ hotels available in Brookline.