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There are 6 ways to get from Rochester to St. Louis by plane, shuttle, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Rochester  •  5h 36m

  1. Fly from Rochester (RST) to St. Louis (STL) RST - STL

$210 - $1,113

Cheapest option

Bus  •  15h 45m

  1. Take the bus from Rochester, MN to Milwaukee 965
  2. Take the bus from Milwaukee, Wi to Chicago, Il
  3. Take the bus from Chicago, Il to St Louis, Mo

$108 - $198

4 alternative options

Shuttle to Minneapolis, fly  •  4h 57m

  1. Take a shuttle bus from 2nd Street Rochester to Minneapolis Airport
  2. Fly from Minneapolis (MSP) to St. Louis (STL) MSP - STL

$154 - $396

Bus, train  •  14h 19m

  1. Take the bus from Rochester, MN to Winona Amtrak Station
  2. Take the train from Winona Amtrak Station to Chicago Union Station
  3. Take the train from Chicago Union Station to St. Louis Gateway Station

$119 - $313

Shuttle, bus  •  17h 20m

  1. Take a shuttle bus from Rochester to Albert Lea. MN
  2. Take the bus from Albert Lea, MN to Des Moines, IA 801 / ...
  3. Take the bus from Des Moines, IA to Mt. Pleasant, IL
  4. Take the bus from Mt. Pleasant, IA to St Louis, MO

$113 - $225

Drive  •  8h 26m

  1. Drive from Rochester to St. Louis 456 miles

$40 - $65

Questions & Answers

The cheapest way to get from Rochester to St. Louis is to drive which costs $40 - $65 and takes 8h 26m.

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The quickest way to get from Rochester to St. Louis is to shuttle and fly which costs $150 - $400 and takes 4h 57m.

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No, there is no direct bus from Rochester to St. Louis. However, there are services departing from Rochester, MN and arriving at St Louis, Mo via Milwaukee, Wi and Chicago, Il. The journey, including transfers, takes approximately 15h 45m.

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The distance between Rochester and St. Louis is 393 miles. The road distance is 456 miles.

Get driving directions

The best way to get from Rochester to St. Louis without a car is to bus and train which takes 14h 19m and costs $110 - $320.

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It takes approximately 5h 36m to get from Rochester to St. Louis, including transfers.

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Rochester to St. Louis bus services, operated by Jefferson Lines, depart from Rochester, MN station.

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The best way to get from Rochester to St. Louis is to fly which takes 5h 36m and costs $210 - $1,200. Alternatively, you can bus, which costs $100 - $200 and takes 15h 45m.

Mode details

There is no direct flight from Rochester Airport to St. Louis Airport. The quickest flight takes 3h 40m and has one stopover.

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Rochester to St. Louis bus services, operated by Greyhound USA, arrive at St Louis, Mo station.

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Map of how to get from Rochester to St. Louis.
Launch map view
  • Distance: 393.2 miles
  • Duration: 5h 36m

What companies run services between Rochester, MN, USA and St. Louis, MO, USA?

United Airlines, Delta and American Airlines fly from Rochester to St. Louis hourly. Alternatively, you can take a bus from Rochester to St. Louis via Milwaukee, Milwaukee, Wi, and Chicago, Il in around 15h 45m.

Airlines
Delta
Website
delta.com
Flights from Rochester to St. Louis via Minneapolis
Ave. Duration
4h 41m
When
Every day
Estimated price
$200 - $1,100
Flights from Rochester to St. Louis via Atlanta
Ave. Duration
6h 29m
When
Every day
Estimated price
$280 - $1,300
Flights from Rochester to St. Louis via Minneapolis, Detroit
Ave. Duration
6h 54m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$250 - $1,200
Flights from Rochester to St. Louis via Minneapolis, Covington
Ave. Duration
7h 55m
When
Monday to Friday
Estimated price
$250 - $1,200
Flights from Minneapolis to St. Louis
Ave. Duration
1h 44m
When
Every day
Estimated price
$270 - $750
Southwest Airlines
Website
southwest.com
Flights from Minneapolis to St. Louis
Ave. Duration
1h 29m
When
Every day
Estimated price
$200 - $900
Flights from Minneapolis to St. Louis via Chicago Midway
Ave. Duration
3h 37m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $900
United Airlines
Website
united.com
Flights from Rochester to St. Louis via Chicago O'Hare
Ave. Duration
4h 34m
When
Every day
Estimated price
$240 - $1,200
Flights from Minneapolis to St. Louis via Chicago O'Hare
Ave. Duration
3h 49m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$290 - $900
American Airlines
Website
aa.com
Flights from Rochester to St. Louis via Chicago O'Hare
Ave. Duration
5h 4m
When
Every day
Estimated price
$220 - $1,100
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Winona Amtrak Station to Chicago Union Station
Ave. Duration
5h 44m
Frequency
3 times a day
Estimated price
$50 - $140
Website
amtrak.com
Coach Seat
$50 - $80
Flexi Coach Seat
$95 - $140
Business Coach Seat
$95 - $140
Room
$240 - $340
Train from Chicago Union Station to St. Louis Gateway Station
Ave. Duration
5h 30m
Frequency
Every 4 hours
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Groome Transportation
Phone
(800) 280-9270
Website
groometransportation.com
Shuttle from 2nd Street Rochester to Minneapolis Airport
Ave. Duration
1h 35m
Frequency
Hourly
Estimated price
$30 - $45
Schedules at
groometransportation.com
Bus from Rochester, MN to Winona Amtrak Station
Ave. Duration
1h 5m
Frequency
Every 3 hours
Estimated price
$25 - $45
Schedules at
groometransportation.com
Amtrak Thruway

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Thruway
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Bus from Rochester, MN to Winona Amtrak Station
Ave. Duration
1h 5m
Frequency
Every 4 hours
Estimated price
$18 - $26
Website
amtrak.com
Jefferson Lines
Phone
800-451-5333
Email
info@jeffersonlines.com
Website
jeffersonlines.com
Bus from Rochester, MN to Milwaukee
Ave. Duration
6h 5m
Frequency
Once daily
Estimated price
$55 - $80
Book at
jeffersonlines.com
Bus from Albert Lea, MN to Des Moines, IA
Ave. Duration
2h 55m
Frequency
Twice daily
Estimated price
$35 - $50
Book at
jeffersonlines.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Milwaukee, Wi to Chicago, Il
Ave. Duration
1h 55m
Frequency
Every 4 hours
Estimated price
$15 - $35
Website
greyhound.com
Economy
$15 - $23
Flexible
$27 - $35
Bus from Chicago, Il to St Louis, Mo
Ave. Duration
5h 45m
Frequency
Every 4 hours
Estimated price
$35 - $85
Website
greyhound.com
Economy
$35 - $55
Flexible
$65 - $85
Land to Air Express
Website
landtoairexpress.com
Shuttle from Rochester to Albert Lea. MN
Ave. Duration
1h 5m
Frequency
Every 4 hours
Estimated price
$8 - $30
Schedules at
landtoairexpress.com
Burlington Trailways
Website
burlingtontrailways.com
Bus from Des Moines, IA to Mt. Pleasant, IL
Ave. Duration
2h 40m
Frequency
Once daily
Estimated price
$29 - $45
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Mt. Pleasant, IA to St Louis, MO
Ave. Duration
7h 40m
Frequency
Once daily
Estimated price
$40 - $100
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com

Want to know more about travelling around United States

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More Questions & Answers

Yes, the driving distance between Rochester to St. Louis is 456 miles. It takes approximately 8h 26m to drive from Rochester to St. Louis.

Get driving directions

United Airlines, American Airlines and Delta offer flights from Rochester Airport to St. Louis Airport.

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There are 203+ hotels available in St. Louis. Prices start at $64 USD per night.

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The best way to get from Rochester to Rochester Airport is to shuttle which takes 15m and costs $7 - $11.

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