There are 5 ways to get from Roanoke to Tupelo by bus (Greyhound), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Roanoke Bus Stop to Nashville Bus Station
- Take the bus from Nashville Bus Station to Memphis Bus Station
- Take the bus from Memphis Bus Station to Tupelo
15h 19m$137–263Fly to Golden Triangle Regional Airport, drive
cheapest- Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Golden Triangle Regional Airport (GTR)ROA - GTR
- Drive from Golden Triangle Regional Airport (GTR) to Tupelo
9h 39m$75–371Drive 602.6 mi
- Drive from Roanoke to Tupelo602.6 mi
10h 33m$110–159Fly to Birmingham–Shuttlesworth International Airport, drive
- Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Birmingham–Shuttlesworth International Airport (BHM)ROA - BHM
- Drive from Birmingham-Airport-BHM to Tupelo
7h 13m$118–594Fly to Huntsville International Airport-Carl T Jones Field, drive
- Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Huntsville International Airport-Carl T Jones Field (HSV)ROA - HSV
- Drive from Huntsville International Airport-Carl T Jones Field (HSV) to Tupelo
7h 26m$97–459
Roanoke Regional Airport-Woodrum Field (ROA) to Golden Triangle Regional Airport (GTR) flights
Questions & Answers
The cheapest way to get from Roanoke to Tupelo is to drive which costs $110 - $160 and takes 10h 33m.
The fastest way to get from Roanoke to Tupelo is to fly and drive which takes 7h 13m and costs $110 - $600.
The distance between Roanoke and Tupelo is 751 miles. The road distance is 606.2 miles.
The best way to get from Roanoke to Tupelo without a car is to bus which takes 15h 19m and costs $130 - $270.
It takes approximately 15h 19m to get from Roanoke to Tupelo, including transfers.
Tupelo is 1h behind Roanoke. It is currently 11:30 PM in Roanoke and 10:30 PM in Tupelo.
Yes, the driving distance between Roanoke to Tupelo is 606 miles. It takes approximately 10h 33m to drive from Roanoke to Tupelo.
There are 34+ hotels available in Tupelo.
What companies run services between Roanoke, VA, USA and Tupelo, MS, USA?
You can take a bus from Roanoke Bus Stop to Tupelo via Nashville Bus Station, Memphis Bus Station, and Tupelo in around 15h 19m.
- Website
- aa.com
Flights from Roanoke Regional Airport-Woodrum Field to Birmingham–Shuttlesworth International Airport via Charlotte
- Ave. Duration
- 4h 21m
- When
- Monday to Saturday
- Estimated price
- $95–550
Flights from Roanoke Regional Airport-Woodrum Field to Birmingham–Shuttlesworth International Airport via Philadelphia
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $150–750
Flights from Roanoke Regional Airport-Woodrum Field to Birmingham–Shuttlesworth International Airport via Chicago O'Hare
- Ave. Duration
- 5h 11m
- When
- Tuesday and Wednesday
- Estimated price
- $150–750
Flights from Roanoke Regional Airport-Woodrum Field to Huntsville International Airport-Carl T Jones Field via Charlotte
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $70–420
Flights from Roanoke Regional Airport-Woodrum Field to Huntsville International Airport-Carl T Jones Field via Chicago O'Hare
- Ave. Duration
- 6h 18m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
- Website
- delta.com
Flights from Roanoke Regional Airport-Woodrum Field to Golden Triangle Regional Airport via Atlanta
- Ave. Duration
- 8h 32m
- When
- Every day
- Estimated price
- $60–350
Flights from Roanoke Regional Airport-Woodrum Field to Golden Triangle Regional Airport via New York La Guardia, Atlanta
- Ave. Duration
- 7h 57m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–500
Flights from Roanoke Regional Airport-Woodrum Field to Golden Triangle Regional Airport via Charlotte, Atlanta
- Ave. Duration
- 7h 31m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- $65–360
Flights from Roanoke Regional Airport-Woodrum Field to Golden Triangle Regional Airport via Washington Dulles, Atlanta
- Ave. Duration
- 7h 37m
- When
- Monday, Tuesday, Wednesday, Friday, and Sunday
- Estimated price
- $85–420
Flights from Roanoke Regional Airport-Woodrum Field to Birmingham–Shuttlesworth International Airport via Atlanta
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $90–550
Flights from Roanoke Regional Airport-Woodrum Field to Huntsville International Airport-Carl T Jones Field via Atlanta
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $75–430
- Website
- united.com
Flights from Roanoke Regional Airport-Woodrum Field to Birmingham–Shuttlesworth International Airport via Chicago O'Hare
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $150–750
Flights from Roanoke Regional Airport-Woodrum Field to Huntsville International Airport-Carl T Jones Field via Washington Dulles
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $90–490
Flights from Roanoke Regional Airport-Woodrum Field to Huntsville International Airport-Carl T Jones Field via Chicago O'Hare
- Ave. Duration
- 7h 25m
- When
- Every day
- Estimated price
- $110–550
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Roanoke Bus Stop to Nashville Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- Once daily
- Estimated price
- $65–120
- Website
- https://www.greyhound.com/
Bus from Nashville Bus Station to Memphis Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $40–80
- Website
- https://www.greyhound.com/
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $20–60
- Website
- https://www.greyhound.com/
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