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How to get fromRoanoke to Key Westby plane, bus (Amtrak), bus, train or car

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There are 6 ways to get from Roanoke to Key West by plane, bus (Amtrak), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Roanoke Regional Airport-Woodrum Field

    best
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Key West International Airport (EYW)plane plane ROA - EYW
    6h 5m
    $111–535

  2. Bus

    1. Take the bus from Roanoke Bus Stop to Charlottesville Union Stationbus bus
    2. Take the bus from Charlottesville Amtrak Station to Richmond Main Street Amtrak Stationbus bus
    3. Take the bus from Richmond to Orlando Bus Stationbus bus
    4. Take the bus from Orlando Bus Station to Miami Airport Stationbus bus
    5. Take the bus from Miami Airport Station to Big Pine Keybus bus
    6. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    33h 21m

  3. Bus, train

    1. Take the bus from Roanoke Bus Stop to Fredericksburg Bus Stopbus bus
    2. Take the train from Fredericksburg Amtrak to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    35h 18m

  4. Drive 1,045.8 mi

    1. Drive from Roanoke to Key Westcar car 1,045.8 mi
    18h 52m
    $191–276

  5. Drive to Greenbrier Valley Airport, fly

    1. Drive from Roanoke to Greenbrier Valley Airport (LWB)car car
    2. Fly from Greenbrier Valley Airport (LWB) to Key West International Airport (EYW)plane plane LWB - EYW
    8h 38m
    $124–581

  6. Train to Lynchburg Regional Airport, fly

    1. Take the train from Roanoke to Lynchburgtrain train
    2. Fly from Lynchburg Regional Airport (LYH) to Key West International Airport (EYW)plane plane LYH - EYW
    9h 22m

Roanoke Regional Airport-Woodrum Field (ROA) to Key West International Airport (EYW) flights

Calendar54Weekly Planes
Duration5h 42mAverage Duration
Ticket$100Cheapest Price
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Questions & Answers

What companies run services between Roanoke, VA, USA and Key West, FL, USA?

American Airlines, Delta, and United Airlines fly from Roanoke Regional Airport-Woodrum Field (ROA) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Roanoke Bus Stop to N Roosevelt & 3rd Street via Charlottesville Union Station, Charlottesville Amtrak Station, Richmond, Orlando Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 33h 21m.

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