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How to get fromRoanoke to Key Westby plane, bus (Greyhound, Amtrak, Flixbus), bus, train or car

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There are 5 ways to get from Roanoke to Key West by plane, bus (Greyhound, Amtrak, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Roanoke Regional Airport-Woodrum Field

    best
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Key West International Airport (EYW)planeROA - EYW
    5h 47m
    $100–457

  2. Bus

    1. Take the bus from Roanoke Bus Stop to Charlottesville Union Stationbus
    2. Take the bus from Charlottesville Amtrak Station to Richmond Main Street Amtrak Stationbus
    3. Take the bus from Richmond to Orlando Bus Stationbus
    4. Take the bus from Orlando Bus Station to Miami Airport Stationbus
    5. Take the bus from Miami Airport Station to Big Pine Keybus
    6. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    33h 22m

  3. Bus, train

    1. Take the bus from Roanoke Bus Stop to Fredericksburg Bus Stopbus
    2. Take the train from Fredericksburg Amtrak to West Palm Beach Amtrak Stationtrain
    3. Take the train from West Palm Beach Station to Miami Airport Stationtrain
    4. Take the bus from Miami Airport Station to Big Pine Keybus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    35h 55m
    $158–429

  4. Drive 1,045.8 mi

    1. Drive from Roanoke to Key Westcar1,045.8 mi
    18h 41m
    $191–276

  5. Drive to Greenbrier Valley Airport, fly

    1. Drive from Roanoke to Greenbrier Valley Airport (LWB)car
    2. Fly from Greenbrier Valley Airport (LWB) to Key West International Airport (EYW)planeLWB - EYW
    6h 42m
    $114–471

Roanoke to Key West by bus, train, and foot

Calendar7Weekly Services
Duration35h 55mAverage Duration
Ticket$158Cheapest Price
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Questions & Answers

What companies run services between Roanoke, VA, USA and Key West, FL, USA?

Allegiant Air, American Airlines, and two other airlines fly from Roanoke Regional Airport-Woodrum Field (ROA) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Roanoke Bus Stop to N Roosevelt & 3rd Street via Charlottesville Union Station, Charlottesville Amtrak Station, Richmond, Orlando Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 33h 22m.

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