There are 6 ways to get from Roanoke to Key Largo by plane, shuttle, bus (Greyhound, Flixbus), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Roanoke Regional Airport-Woodrum Field to Miami International Airport, shuttle
best- Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Miami International Airport (MIA)plane ROA - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
8h 10m$189–574Drive 948.7 mi
cheapest- Drive from Roanoke to Key Largocar 948.7 mi
16h 36m$174–251Bus
- Take the bus from Roanoke Bus Stop to Lynchburg Transit Centerbus
- Take the bus from Lynchburg Transit Center to Richmondbus
- Take the bus from Richmond to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
27h 45m$177–288Train, bus
- Take the train from Roanoke to Alexandriatrain
- Take the train from Alexandria to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
31h 50m$358–795Fly Roanoke Regional Airport-Woodrum Field to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Fort Lauderdale–Hollywood International Airport (FLL)plane ROA - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
8h 31m$209–604Train, train to Piedmont Triad International Airport, fly to Miami International Airport, shuttle
- Take the train from Roanoke to Lynchburgtrain
- Take the train from Lynchburg to Greensborotrain
- Fly from Piedmont Triad International Airport (GSO) to Miami International Airport (MIA)plane GSO - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
10h 5m$267–815
Roanoke to Key Largo by bus and foot
Comparing Your Travel Options
The cheapest way to get from Roanoke to Key Largo is to drive which costs $170 - $250 and takes 16h 36m.
The fastest way to get from Roanoke to Key Largo is to fly and shuttle which takes 8h 10m and costs $180 - $600.
No, there is no direct bus from Roanoke to Key Largo. However, there are services departing from Roanoke Bus Stop and arriving at Key Largo Bus Stop via Lynchburg Transit Center, Richmond and Miami Airport Station. The journey, including transfers, takes approximately 27h 45m.
The distance between Roanoke and Key Largo is 866 miles. The road distance is 954.2 miles.
The best way to get from Roanoke to Key Largo without a car is to bus which takes 27h 45m and costs $170 - $290.
It takes approximately 8h 10m to get from Roanoke to Key Largo, including transfers.
Roanoke to Key Largo bus services, operated by Greyhound USA, depart from Roanoke Bus Stop station.
Roanoke to Key Largo bus services, operated by Greyhound USA, arrive at Lynchburg Transit Center station.
Yes, the driving distance between Roanoke to Key Largo is 954 miles. It takes approximately 16h 36m to drive from Roanoke to Key Largo.
Book your Roanoke to Key Largo bus tickets online with Omio and FlixBus.
What companies run services between Roanoke, VA, USA and Key Largo, FL, USA?
You can take a bus from Roanoke Bus Stop to Key Largo Bus Stop via Lynchburg Transit Center, Richmond, Richmond, and Miami Airport Station in around 27h 45m.
- Website
- aa.com
Flights from Roanoke Regional Airport-Woodrum Field to Miami International Airport via Charlotte
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $85–440
Flights from Roanoke Regional Airport-Woodrum Field to Miami International Airport via Philadelphia
- Ave. Duration
- 6h 29m
- When
- Every day
- Estimated price
- $120–550
Flights from Roanoke Regional Airport-Woodrum Field to Miami International Airport via Chicago O'Hare
- Ave. Duration
- 6h 23m
- When
- Every day
- Estimated price
- $140–650
Flights from Roanoke Regional Airport-Woodrum Field to Fort Lauderdale–Hollywood International Airport via Charlotte
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $85–450
Flights from Roanoke Regional Airport-Woodrum Field to Fort Lauderdale–Hollywood International Airport via Philadelphia
- Ave. Duration
- 7h
- When
- Every day
- Estimated price
- $120–600
Flights from Roanoke Regional Airport-Woodrum Field to Fort Lauderdale–Hollywood International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 34m
- When
- Every day
- Estimated price
- $180–750
Flights from Piedmont Triad International Airport to Miami International Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- $95–550
Flights from Piedmont Triad International Airport to Miami International Airport via Charlotte
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $100–550
Flights from Piedmont Triad International Airport to Miami International Airport via Reagan Washington
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $130–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Roanoke to Alexandria
- Ave. Duration
- 4h 47m
- Frequency
- Twice daily
- Estimated price
- $55–130
- Website
- Amtrak
Train from Alexandria to Hollywood Amtrak Station
- Ave. Duration
- 22h 36m
- Frequency
- Twice daily
- Estimated price
- $290–650
- Website
- Amtrak
Train from Roanoke to Lynchburg
- Ave. Duration
- 1h 14m
- Frequency
- Twice daily
- Estimated price
- $13–30
- Website
- Amtrak
Train from Lynchburg to Greensboro
- Ave. Duration
- 2h 9m
- Frequency
- Once daily
- Estimated price
- $28–65
- Website
- Amtrak
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $100–130
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $120–150
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $100–130
- Website
- Keys Shuttle
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Booking & Getting There
There are 342+ hotels available in Key Largo.




