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How to get fromRoanoke to Florida Keysby plane, bus (Greyhound, Amtrak, Flixbus), bus, train or car

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There are 5 ways to get from Roanoke to Florida Keys by plane, bus (Greyhound, Amtrak, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Roanoke Regional Airport-Woodrum Field

    best
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Key West International Airport (EYW)plane plane ROA - EYW
    9h 4m
    $151–623

  2. Bus

    1. Take the bus from Roanoke Bus Stop to Charlottesville Union Stationbus bus
    2. Take the bus from Charlottesville Amtrak Station to Richmond Main Street Amtrak Stationbus bus
    3. Take the bus from Richmond to Orlando Bus Stationbus bus
    4. Take the bus from Orlando Bus Station to Miami Airport Stationbus bus
    5. Take the bus from Miami Airport Station to Big Pine Keybus bus
    32h 35m

  3. Bus, train

    1. Take the bus from Roanoke Bus Stop to Fredericksburg Bus Stopbus bus
    2. Take the train from Fredericksburg Amtrak to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    34h 46m
    $231–481

  4. Drive 1,030.4 mi

    1. Drive from Roanoke to Florida Keyscar car 1,030.4 mi
    18h 29m
    $189–272

  5. Train to Lynchburg Regional Airport, fly

    1. Take the train from Roanoke to Lynchburgtrain train
    2. Fly from Lynchburg Regional Airport (LYH) to Key West International Airport (EYW)plane plane LYH - EYW
    11h 29m
    $156–827

Roanoke Regional Airport-Woodrum Field (ROA) to Key West International Airport (EYW) flights

Calendar70Weekly Planes
Duration6h 5mAverage Duration
Ticket$103Cheapest Price
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Questions & Answers

What companies run services between Roanoke, VA, USA and Florida Keys, FL, USA?

American Airlines, Delta, and two other airlines fly from Roanoke Regional Airport-Woodrum Field (ROA) to Key West International Airport (EYW) every 3 hours. Alternatively, you can take a bus from Roanoke Bus Stop to Florida Keys via Charlottesville Union Station, Charlottesville Amtrak Station, Richmond, Orlando Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 32h 35m.

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