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How to get fromRoanoke to Florida Keysby plane, bus (Greyhound, Amtrak, Flixbus), bus, train or car

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There are 6 ways to get from Roanoke to Florida Keys by plane, bus (Greyhound, Amtrak, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Roanoke Regional Airport-Woodrum Field

    best
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Key West International Airport (EYW)planeROA - EYW
    8h 33m
    $136–513
  2. Bus

    1. Take the bus from Roanoke Bus Stop to Charlottesville Union Stationbus
    2. Take the bus from Charlottesville Amtrak Station to Richmond Main Street Amtrak Stationbus
    3. Take the bus from Richmond to Orlando Bus Stationbus
    4. Take the bus from Orlando Bus Station to Miami Airport Stationbus
    5. Take the bus from Miami Airport Station to Big Pine Keybus
    32h 35m
  3. Bus, train

    1. Take the bus from Roanoke Bus Stop to Fredericksburg Bus Stopbus
    2. Take the train from Fredericksburg Amtrak to Miami Amtrak Stationtrain
    3. Take the bus from Miami Airport Station to Big Pine Keybus
    34h 44m
    $184–433
  4. Drive 1,030.4 mi

    1. Drive from Roanoke to Florida Keyscar1,030.4 mi
    18h 18m
    $189–272
  5. Drive to Greenbrier Valley Airport, fly

    1. Drive from Roanoke to Greenbrier Valley Airport (LWB)car
    2. Fly from Greenbrier Valley Airport (LWB) to Key West International Airport (EYW)planeLWB - EYW
    9h 29m
    $150–537
  6. Train to Lynchburg Regional Airport, fly

    1. Take the train from Roanoke to Lynchburgtrain
    2. Fly from Lynchburg Regional Airport (LYH) to Key West International Airport (EYW)planeLYH - EYW
    11h 33m
    $146–727

Roanoke to Florida Keys by bus, train, taxi, and foot

Calendar7Weekly Services
Duration34h 44mAverage Duration
Ticket$184Cheapest Price
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Questions & Answers

What companies run services between Roanoke, VA, USA and Florida Keys, FL, USA?

Allegiant Air, American Airlines, and two other airlines fly from Roanoke Regional Airport-Woodrum Field (ROA) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Roanoke Bus Stop to Florida Keys via Charlottesville Union Station, Charlottesville Amtrak Station, Richmond, Orlando Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 32h 35m.

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