There are 5 ways to get from Roanoke to Chicago by plane, bus (Greyhound, Flixbus), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Roanoke Regional Airport-Woodrum Field
best- Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Chicago O'Hare International Airport (ORD)plane ROA - ORD
4h 27m$51–289Bus
- Take the bus from Roanoke Bus Stop to Nashville Bus Stationbus Greyhound US0600
- Take the bus from Nashville Bus Station to Chicago Bus Stationbus Greyhound US0100
18h 45m$123–279Train (Amtrak)
- Take the train from Roanoke to Charlottesvilletrain Northeast Regional
- Take the train from Charlottesville to Chicago Union Stationtrain Cardinal
24h 36m$146–1,036Drive 647.7 mi
- Drive from Roanoke to Chicagocar 647.7 mi
11h 37m$119–171Drive to Greenbrier Valley Airport, fly
- Drive from Roanoke to Greenbrier Valley Airport (LWB)car
- Fly from Greenbrier Valley Airport (LWB) to Chicago O'Hare International Airport (ORD)plane LWB - ORD
4h 29m$75–393
Roanoke to Chicago by bus
Questions & Answers
The cheapest way to get from Roanoke to Chicago is to drive which costs $110 - $180 and takes 11h 37m.
The fastest way to get from Roanoke to Chicago is to fly which takes 4h 27m and costs $50 - $290.
No, there is no direct bus from Roanoke to Chicago station. However, there are services departing from Roanoke Bus Stop and arriving at Chicago Bus Station via Nashville Bus Station. The journey, including transfers, takes approximately 18h 45m.
No, there is no direct train from Roanoke to Chicago station. However, there are services departing from Roanoke and arriving at Chicago Union Station via Charlottesville. The journey, including transfers, takes approximately 24h 36m.
The distance between Roanoke and Chicago is 558 miles. The road distance is 651.5 miles.
The best way to get from Roanoke to Chicago without a car is to bus which takes 18h 45m and costs $120 - $280.
It takes approximately 4h 27m to get from Roanoke to Chicago, including transfers.
Roanoke to Chicago bus services, operated by Greyhound USA, depart from Roanoke Bus Stop station.
Roanoke to Chicago train services, operated by Amtrak Northeast Regional, depart from Roanoke station.
The best way to get from Roanoke to Chicago is to fly which takes 4h 27m and costs $50 - $290. Alternatively, you can bus, which costs $120 - $280 and takes 18h 45m, you could also train, which costs $140 - $1,100 and takes 24h 36m.
What companies run services between Roanoke, VA, USA and Chicago, IL, USA?
American Airlines, United Airlines, and Delta fly from Roanoke Regional Airport-Woodrum Field (ROA) to Chicago O'Hare International Airport (ORD) every 2 hours. Alternatively, you can take a bus from Roanoke Bus Stop to Chicago Bus Station via Nashville Bus Station in around 18h 45m.
- Website
- aa.com
Flights from Roanoke Regional Airport-Woodrum Field to Chicago O'Hare International Airport
- Ave. Duration
- 2h 18m
- When
- Every day
- Estimated price
- $45–280
Flights from Roanoke Regional Airport-Woodrum Field to Chicago O'Hare International Airport via Charlotte
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $55–310
Flights from Roanoke Regional Airport-Woodrum Field to Chicago O'Hare International Airport via Philadelphia
- Ave. Duration
- 5h 17m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $65–340
Flights from Greenbrier Valley Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h
- When
- Monday, Friday, and Sunday
- Estimated price
- $60–370
- Website
- united.com
Flights from Roanoke Regional Airport-Woodrum Field to Chicago O'Hare International Airport
- Ave. Duration
- 2h 12m
- When
- Every day
- Estimated price
- $45–280
Flights from Roanoke Regional Airport-Woodrum Field to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $55–310
- Website
- delta.com
Flights from Roanoke Regional Airport-Woodrum Field to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $65–340
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Roanoke to Charlottesville
- Ave. Duration
- 2h 28m
- Frequency
- Twice daily
- Estimated price
- $15–240
- Website
- https://www.amtrak.com/home
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $15–240
- Business Class
- $65–280
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Charlottesville to Chicago Union Station
- Ave. Duration
- 21h 8m
- Frequency
- 3 times a week
- Estimated price
- $130–800
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Roanoke Bus Stop to Nashville Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- Once daily
- Estimated price
- $65–100
- Website
- https://www.greyhound.com/
Bus from Nashville Bus Station to Chicago Bus Station
- Ave. Duration
- 9h 40m
- Frequency
- 4 times a day
- Estimated price
- $55–180
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Nashville Bus Station to Chicago Bus Station
- Ave. Duration
- 9h 25m
- Frequency
- 3 times a day
- Estimated price
- $60–160
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Roanoke to Chicago bus services, operated by Greyhound USA, arrive at Nashville Bus Station.
Chicago is 1h behind Roanoke. It is currently 12:15 PM in Roanoke and 11:15 AM in Chicago.
Roanoke to Chicago train services, operated by Amtrak Northeast Regional, arrive at Charlottesville station.
Yes, the driving distance between Roanoke to Chicago is 652 miles. It takes approximately 11h 37m to drive from Roanoke to Chicago.
Book your Roanoke to Chicago train tickets online with Omio.
Book your Roanoke to Chicago bus tickets online with Omio and FlixBus.
There are 1068+ hotels available in Chicago.