Rome2Rio

How to get fromResearch Triangle to St. Louisby plane, bus (Flixbus, Greyhound), train (Amtrak), car, train or bus

Find Transport to St. Louis

See all options

There are 5 ways to get from Research Triangle to St. Louis by plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL)plane plane RDU - STL
    2h 53m
    $308–729
  2. Bus

    cheapest
    1. Take the bus from Durham to Atlanta Bus Stationbus bus FlixBus N2471 / ...
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus FlixBus N2521
    20h 45m
    $110–252
  3. Train (Amtrak)

    1. Take the train from Cary to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    31h 25m
    $395–856
  4. Drive 768.4 mi

    1. Drive from Research Triangle to St. Louiscar car 768.4 mi
    14h 5m
    $141–203
  5. Train, bus

    1. Take the train from Cary to Pittsburgh Amtrak Stationtrain train Floridian
    2. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus bus Greyhound US0421
    31h 34m
    $260–562

Research Triangle to St. Louis by bus

Calendar7Weekly Buses
Duration20h 45mAverage Duration
Ticket$110Cheapest Price
See schedules

Questions & Answers

What companies run services between Research Triangle, NC, USA and St. Louis, MO, USA?

Southwest Airlines, American Airlines, and Delta fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from RDU Airport at Terminal 1 to St Louis Bus Station via Regional Transit Center, Pettigrew St at Parking Deck, Durham, and Atlanta Bus Station in around 20h 45m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers