There are 5 ways to get from Research Triangle to St. Louis by plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL)plane RDU - STL
2h 53m$308–729Bus
cheapest- Take the bus from Durham to Atlanta Bus Stationbus FlixBus N2471 / ...
- Take the bus from Atlanta Bus Station to St Louis Bus Stationbus FlixBus N2521
20h 45m$110–252Train (Amtrak)
- Take the train from Cary to Chicago Union Stationtrain Floridian
- Take the train from Chicago Union Station to St. Louistrain Lincoln Service / ...
31h 25m$395–856Drive 768.4 mi
- Drive from Research Triangle to St. Louiscar 768.4 mi
14h 5m$141–203Train, bus
- Take the train from Cary to Pittsburgh Amtrak Stationtrain Floridian
- Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus Greyhound US0421
31h 34m$260–562
Research Triangle to St. Louis by bus
Questions & Answers
The cheapest way to get from Research Triangle to St. Louis is to bus which costs $110 - $260 and takes 20h 45m.
The fastest way to get from Research Triangle to St. Louis is to fly which takes 2h 53m and costs $300 - $750.
No, there is no direct bus from Research Triangle to St. Louis station. However, there are services departing from RDU Airport at Terminal 1 and arriving at St Louis Bus Station via Regional Transit Center, Durham and Atlanta Bus Station. The journey, including transfers, takes approximately 20h 45m.
The distance between Research Triangle and St. Louis is 684 miles. The road distance is 772.9 miles.
The best way to get from Research Triangle to St. Louis without a car is to bus which takes 20h 45m and costs $110 - $260.
It takes approximately 2h 53m to get from Research Triangle to St. Louis, including transfers.
Research Triangle to St. Louis bus services, operated by Flixbus USA, depart from Durham station.
The best way to get from Research Triangle to St. Louis is to fly which takes 2h 53m and costs $300 - $750. Alternatively, you can bus, which costs $110 - $260 and takes 20h 45m, you could also train, which costs $390 - $900 and takes 31h 25m.
Research Triangle to St. Louis bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Research Triangle to St. Louis is 773 miles. It takes approximately 14h 5m to drive from Research Triangle to St. Louis.
What companies run services between Research Triangle, NC, USA and St. Louis, MO, USA?
Southwest Airlines, American Airlines, and Delta fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from RDU Airport at Terminal 1 to St Louis Bus Station via Regional Transit Center, Pettigrew St at Parking Deck, Durham, and Atlanta Bus Station in around 20h 45m.
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- $130–750
Flights from Raleigh-Durham International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 4h 21m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–750
Flights from Raleigh-Durham International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 4h 26m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $150–850
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 4h 22m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–800
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Lambert–St. Louis International Airport via Charlotte
- Ave. Duration
- 4h 10m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $130–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Cary to Chicago Union Station
- Ave. Duration
- 25h 21m
- Frequency
- Once daily
- Estimated price
- $290–650
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $75–170
- Website
- https://www.amtrak.com/home.html
Train from Cary to Pittsburgh Amtrak Station
- Ave. Duration
- 15h 24m
- Frequency
- Once daily
- Estimated price
- $160–360
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Durham to Atlanta Bus Station
- Ave. Duration
- 7h
- Frequency
- 4 times a day
- Estimated price
- $45–85
- Schedules at
- flixbus.com
Bus from Atlanta Bus Station to St Louis Bus Station
- Ave. Duration
- 10h 40m
- Frequency
- Once daily
- Estimated price
- $65–120
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Durham to Atlanta Bus Station
- Ave. Duration
- 8h 25m
- Frequency
- 4 times a day
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
Bus from Pittsburgh Intermodal Station to St Louis Bus Station
- Ave. Duration
- 12h 55m
- Frequency
- 3 times a day
- Estimated price
- $100–200
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 381+ hotels available in St. Louis.






