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How to get fromRaleigh to St. Louisby plane, bus (Greyhound, Flixbus), train (Amtrak), car or bus (Greyhound)

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There are 6 ways to get from Raleigh to St. Louis by plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Raleigh-Durham International Airport

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL)plane plane RDU - STL
    4h 40m
    $203–465

  2. Bus

    cheapest
    1. Take the bus from Raleigh Bus Station to Atlanta Bus Stationbus bus Greyhound US0670 / ...
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus FlixBus N2521
    20h 52m
    $106–321

  3. Train (Amtrak)

    1. Take the train from Raleigh Union Station to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    30h 23m
    $174–497

  4. Drive 779.4 mi

    1. Drive from Raleigh to St. Louiscar car 779.4 mi
    14h 13m
    $143–206

  5. Drive to Albert J. Ellis Airport, fly

    1. Drive from Raleigh to Albert J. Ellis Airport (OAJ)car car
    2. Fly from Albert J. Ellis Airport (OAJ) to Lambert–St. Louis International Airport (STL)plane plane OAJ - STL
    7h 16m
    $132–680

  6. Bus via Columbus

    1. Take the bus from Raleigh Bus Station to Winston Salem(Trans Center)bus bus
    2. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    3. Take the bus from Columbus to St Louis Bus Stationbus bus
    23h 47m
    $107–236

Raleigh to St. Louis by bus

Calendar7Weekly Buses
Duration20h 52mAverage Duration
Ticket$106Cheapest Price
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Questions & Answers

What companies run services between Raleigh, NC, USA and St. Louis, MO, USA?

Southwest Airlines, Delta, and American Airlines fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a bus from GoRaleigh Station to St Louis Bus Station via Capital Blvd at Crabtree Blvd, Raleigh Bus Station, and Atlanta Bus Station in around 20h 52m.

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