There are 9 ways to get from Raleigh to Middlesboro by plane, car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Raleigh-Durham International Airport to Mcghee Tyson Airport, drive
best- Fly from Raleigh-Durham International Airport (RDU) to Mcghee Tyson Airport (TYS)plane RDU - TYS
- Drive from Mcghee Tyson Airport (TYS) to Middlesborocar
6h 47m$243–452Drive 341.4 mi
cheapest- Drive from Raleigh to Middlesborocar 341.4 mi
6h 53m$63–90Train, bus, drive
- Take the train from Raleigh Union Station to Durham Amtrak Stationtrain
- Take the bus from Durham to Atlanta Downtownbus
- Take the bus from Atlanta Bus Station to Londonbus
- Drive from London to Middlesborocar
16h 50m$113–228Fly Raleigh-Durham International Airport to Tri-Cities Regional Tn/Va Airport, drive
- Fly from Raleigh-Durham International Airport (RDU) to Tri-Cities Regional Tn/Va Airport (TRI)plane RDU - TRI
- Drive from Tri-Cities-Regional-Airport-TRI to Middlesborocar
7h 4m$82–488Train to Charlotte Douglas International Airport, fly to Mcghee Tyson Airport, drive
- Take the train from Raleigh Union Station to Charlotte Amtrak Stationtrain
- Fly from Charlotte Douglas International Airport (CLT) to Mcghee Tyson Airport (TYS)plane CLT - TYS
- Drive from Mcghee Tyson Airport (TYS) to Middlesborocar
8h 19m$113–539Train to Charlotte Douglas International Airport, fly to Tri-Cities Regional Tn/Va Airport, drive
- Take the train from Raleigh Union Station to Charlotte Amtrak Stationtrain
- Fly from Charlotte Douglas International Airport (CLT) to Tri-Cities Regional Tn/Va Airport (TRI)plane CLT - TRI
- Drive from Tri-Cities-Regional-Airport-TRI to Middlesborocar
8h 26m$97–435Train, bus, drive via Charlotte
- Take the train from Raleigh Union Station to Charlotte Amtrak Stationtrain
- Take the bus from Charlotte, NC to Atlantabus Nyc
- Take the bus from Atlanta Bus Station to Londonbus
- Drive from London to Middlesborocar
17h 7m$162–242Bus, drive
- Take the bus from Raleigh Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Londonbus
- Drive from London to Middlesborocar
17h 38m$100–255Bus, drive via Athens
- Take the bus from Raleigh to Marathon Gas - Oconee Loop - Athensbus
- Take the bus from Marathon Gas - Oconee Loop - Athens to Atlantabus
- Take the bus from Atlanta Bus Station to Londonbus
- Drive from London to Middlesborocar
20h 33m$177–320
Raleigh-Durham International Airport (RDU) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Raleigh to Middlesboro is to drive which costs $60 - $90 and takes 6h 53m.
The fastest way to get from Raleigh to Middlesboro is to fly and drive which takes 6h 47m and costs $240 - $460.
The distance between Raleigh and Middlesboro is 380 miles. The road distance is 343.4 miles.
It takes approximately 6h 47m to get from Raleigh to Middlesboro, including transfers.
Yes, the driving distance between Raleigh to Middlesboro is 343 miles. It takes approximately 6h 53m to drive from Raleigh to Middlesboro.
There are 26+ hotels available in Middlesboro.
What companies run services between Raleigh, NC, USA and Middlesboro, KY, USA?
There is no direct connection from Raleigh to Middlesboro. However, you can take the line 100 bus to RDU Airport at Terminal 1, walk to Raleigh-Durham-Airport-RDU airport, fly to Mcghee Tyson Airport (TYS), then drive to Middlesboro. Alternatively, you can take a train from Raleigh Union Station to Middlesboro via Durham Amtrak Station, Durham, Atlanta Downtown, Civic Center Station, Garnett Station, Atlanta Bus Station, and London in around 16h 50m.
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Mcghee Tyson Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $90–600
Flights from Raleigh-Durham International Airport to Mcghee Tyson Airport via Reagan Washington
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $120–750
Flights from Raleigh-Durham International Airport to Tri-Cities Regional Tn/Va Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $65–460
Flights from Raleigh-Durham International Airport to Tri-Cities Regional Tn/Va Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 50m
- When
- Tuesday, Wednesday, Friday, and Saturday
- Estimated price
- $210–950
Flights from Raleigh-Durham International Airport to Tri-Cities Regional Tn/Va Airport via Chicago O'Hare
- Ave. Duration
- 7h 45m
- When
- Every day
- Estimated price
- $140–700
Flights from Charlotte Douglas International Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 18m
- When
- Every day
- Estimated price
- $65–480
Flights from Charlotte Douglas International Airport to Tri-Cities Regional Tn/Va Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $45–370
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $110–700
Flights from Raleigh-Durham International Airport to Tri-Cities Regional Tn/Va Airport via Atlanta
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $95–550
Flights from Charlotte Douglas International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 3h 27m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $85–550
- Website
- united.com
Flights from Raleigh-Durham International Airport to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $120–750
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Mcghee Tyson Airport via Baltimore
- Ave. Duration
- 6h 20m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $130–750
Flights from Raleigh-Durham International Airport to Mcghee Tyson Airport via Nashville
- Ave. Duration
- 6h 45m
- When
- Monday, Thursday, and Friday
- Estimated price
- $120–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Raleigh Union Station to Durham Amtrak Station
- Ave. Duration
- 30 min
- Frequency
- 5 times a day
- Estimated price
- $10–11
- Website
- https://www.amtrak.com/home.html
Train from Raleigh Union Station to Charlotte Amtrak Station
- Ave. Duration
- 3h 10m
- Frequency
- 5 times a day
- Estimated price
- $29–34
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Durham to Atlanta Downtown
- Ave. Duration
- 6h 45m
- Frequency
- 5 times a week
- Estimated price
- $45–110
- Schedules at
- flixbus.com
Bus from Raleigh Bus Station to Atlanta Bus Station
- Ave. Duration
- 7h 40m
- Frequency
- Twice daily
- Estimated price
- $50–150
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Atlanta Bus Station to London
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Raleigh Bus Station to Atlanta Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- Every 4 hours
- Estimated price
- $45–95
- Website
- https://www.greyhound.com/
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from Charlotte, NC to Atlanta
- Ave. Duration
- 3h 20m
- Frequency
- 3 times a day
- Estimated price
- $50–70
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Raleigh Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h 30m
- Frequency
- Once daily
- Estimated price
- $95–110
- Schedules at
- southeasternstages.com
Bus from Raleigh to Marathon Gas - Oconee Loop - Athens
- Ave. Duration
- 8h 40m
- Frequency
- Once daily
- Estimated price
- $95–120
- Schedules at
- southeasternstages.com
Bus from Marathon Gas - Oconee Loop - Athens to Atlanta
- Ave. Duration
- 1h 20m
- Frequency
- Twice daily
- Estimated price
- $27–95
- Schedules at
- southeasternstages.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide










