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There are 6 ways to get from Raleigh to Knoxville by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Raleigh/Durham  •  4 h 52 min

  1. Fly from Raleigh/Durham (RDU) to Knoxville (TYS) RDU - TYS

$227 - $393

Cheapest option

Bus  •  8 h 35 min

  1. Take the bus from Raleigh, Nc to Knoxville, Tn 4845

$35 - $95

4 alternative options

Bus to Fayetteville Municipal, fly  •  5 h 36 min

  1. Take the bus from Raleigh, Nc to Fayetteville, Nc
  2. Fly from Fayetteville Municipal (FAY) to Knoxville (TYS) FAY - TYS

$294 - $1,318

Train to Charlotte, fly  •  6 h 33 min

  1. Take the train from Raleigh Union Station to Charlotte Amtrak Station
  2. Fly from Charlotte (CLT) to Knoxville (TYS) CLT - TYS

$277 - $1,166

Train, bus  •  9 h 56 min

  1. Take the train from Raleigh Union Station to High Point Amtrak Station Piedmont / ...
  2. Take the bus from Winston Salem, Nc to Knoxville, Tn 4845

$63 - $141

Drive  •  6 h 21 min

  1. Drive from Raleigh to Knoxville 363.8 miles

$35 - $55

Questions & Answers

The cheapest way to get from Raleigh to Knoxville is to drive which costs $35 - $55 and takes 6 h 21 min.

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The quickest way to get from Raleigh to Knoxville is to fly which costs $220 - $400 and takes 4 h 52 min.

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Yes, there is a direct bus departing from Raleigh, Nc and arriving at Knoxville, Tn. Services depart once daily, and operate every day. The journey takes approximately 8 h 35 min.

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The distance between Raleigh and Knoxville is 298 miles. The road distance is 363.8 miles.

Get driving directions

The best way to get from Raleigh to Knoxville without a car is to bus which takes 8 h 35 min and costs $35 - $95.

More details

It takes approximately 4 h 52 min to get from Raleigh to Knoxville, including transfers.

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Raleigh to Knoxville bus services, operated by Greyhound USA, depart from Raleigh, Nc station.

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The best way to get from Raleigh to Knoxville is to fly which takes 4 h 52 min and costs $220 - $400. Alternatively, you can bus, which costs $35 - $95 and takes 8 h 35 min.

Mode details

There is no direct flight from Raleigh/Durham Airport to Knoxville Airport. The quickest flight takes 3 h 4 min and has one stopover.

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Raleigh to Knoxville bus services, operated by Greyhound USA, arrive at Knoxville, Tn station.

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Map of how to get from Raleigh to Knoxville.
Launch map view
  • Distance: 297.7 miles
  • Duration: 4 h 52 min

What companies run services between Raleigh, NC, USA and Knoxville, TN, USA?

American Airlines, Delta and United Airlines fly from Raleigh to Knoxville hourly. Alternatively, Greyhound USA operates a bus from Raleigh to Knoxville once daily. Tickets cost $35 - $95 and the journey takes 8 h 35 min.

Airlines
American Airlines
Website
aa.com
Flights from Raleigh/Durham to Knoxville via Charlotte
Ave. Duration
3 h 24 min
When
Every day
Estimated price
$260 - $460
Flights from Raleigh/Durham to Knoxville via Philadelphia
Ave. Duration
4 h 27 min
When
Every day
Estimated price
$260 - $460
Flights from Raleigh/Durham to Knoxville via Chicago O'Hare
Ave. Duration
5 h 1 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$260 - $460
Flights from Raleigh/Durham to Knoxville via Reagan Washington
Ave. Duration
5 h 45 min
When
Every day
Estimated price
$260 - $460
Flights from Fayetteville Municipal to Knoxville via Charlotte
Ave. Duration
3 h 37 min
When
Every day
Estimated price
$210 - $1,200
Flights from Fayetteville Municipal to Knoxville via Charlotte, Reagan Washington
Ave. Duration
6 h 15 min
When
Every day
Estimated price
$280 - $1,300
Flights from Fayetteville Municipal to Knoxville via Charlotte, Chicago O'Hare
Ave. Duration
6 h 51 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$310 - $1,400
Flights from Charlotte to Knoxville
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$180 - $1,000
Delta
Website
delta.com
Flights from Raleigh/Durham to Knoxville via Atlanta
Ave. Duration
3 h 57 min
When
Every day
Estimated price
$250 - $460
Flights from Raleigh/Durham to Knoxville via Detroit
Ave. Duration
4 h 25 min
When
Saturday
Estimated price
$250 - $460
Flights from Raleigh/Durham to Knoxville via New York La Guardia
Ave. Duration
5 h 43 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$250 - $460
Flights from Fayetteville Municipal to Knoxville via Atlanta
Ave. Duration
4 h 33 min
When
Every day
Estimated price
$220 - $1,200
United Airlines
Website
united.com
Flights from Raleigh/Durham to Knoxville via Washington Dulles
Ave. Duration
3 h 45 min
When
Every day
Estimated price
$200 - $750
Flights from Fayetteville Municipal to Knoxville via Washington Dulles
Ave. Duration
4 h 4 min
When
Every day
Estimated price
$270 - $1,300
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Raleigh Union Station to Charlotte Amtrak Station
Ave. Duration
3 h 10 min
Frequency
4 times a day
Estimated price
$35 - $90
Website
amtrak.com
Coach Seat
$35 - $60
Flexi Coach Seat
$65 - $100
Business Coach Seat
$65 - $90
Room
$190 - $260
Train from Raleigh Union Station to High Point Amtrak Station
Ave. Duration
1 h 48 min
Frequency
4 times a day
Estimated price
$29 - $65
Website
amtrak.com
Coach Seat
$29 - $45
Flexi Coach Seat
$50 - $75
Business Coach Seat
$45 - $65
Room
$150 - $220
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Raleigh, Nc to Fayetteville, Nc
Ave. Duration
1 h 5 min
Frequency
Every 2 hours
Estimated price
$13 - $28
Website
greyhound.com
Economy
$13 - $19
Flexible
$22 - $28
Bus from Raleigh, Nc to Knoxville, Tn
Ave. Duration
8 h 35 min
Frequency
Once daily
Estimated price
$35 - $95
Website
greyhound.com
Economy
$35 - $65
Flexible
$70 - $95
Bus from Winston Salem, Nc to Knoxville, Tn
Ave. Duration
5 h 30 min
Frequency
Once daily
Estimated price
$30 - $75
Website
greyhound.com
Economy
$30 - $50
Flexible
$55 - $75

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Yes, the driving distance between Raleigh to Knoxville is 364 miles. It takes approximately 6 h 21 min to drive from Raleigh to Knoxville.

Get driving directions

United Airlines, American Airlines and Delta offer flights from Raleigh/Durham Airport to Knoxville Airport.

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Book your Raleigh to Knoxville bus tickets online with Greyhound.

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There are 106+ hotels available in Knoxville. Prices start at $54 USD per night.

More details

The best way to get from Raleigh to Raleigh/Durham Airport is to line 100 bus which takes 25 min and costs $2 - $3.

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