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There are 4 ways to get from Quito to Santiago by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  7 h 52 min

  1. Fly from Quito (UIO) to Santiago (SCL) UIO - SCL

$213 - $1,033

3 alternative options

Bus Linea de Los Andes  •  3 days 7 h

  1. Take the bus from Quito to Rumichaca, Ecuador Via Cucuta / ...
  2. Take the bus from Rumichaca to Santiago Via Santiago de Chile / ...

$325 - $645

Bus  •  3 days 9 h

  1. Take the bus from Quito to Santiago Via Cucuta

$400

Drive  •  2 days 19 h

  1. Drive from Quito to Santiago 3232.2 miles

$500 - $800

Questions & Answers

The cheapest way to get from Quito to Santiago is to fly which costs $210 - $1,100 and takes 7 h 52 min.

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The quickest way to get from Quito to Santiago is to fly which costs $210 - $1,100 and takes 7 h 52 min.

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No, there is no direct bus from Quito to Santiago. However, there are services departing from San Diego and arriving at Santiago via Quito and Rumichaca. The journey, including transfers, takes approximately 3 days 7 h.

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The distance between Quito and Santiago is 3785 km. The road distance is 5171.6 km.

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The best way to get from Quito to Santiago without a car is to bus which takes 3 days 7 h and costs $320 - $650.

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It takes approximately 7 h 52 min to get from Quito to Santiago, including transfers.

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Quito to Santiago bus services, operated by Skybus, depart from Quito station.

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The best way to get from Quito to Santiago is to fly which takes 7 h 52 min and costs $210 - $1,100. Alternatively, you can bus, which costs $320 - $650 and takes 3 days 7 h.

Mode details

There is no direct flight from Quito Airport to Santiago Airport. The quickest flight takes 6 h 56 min and has one stopover.

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Quito to Santiago bus services, operated by Linea de Los Andes, arrive at Santiago station.

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Map of how to get from Quito to Santiago.
Launch map view
  • Distance: 2365.8 miles
  • Duration: 7 h 52 min

What companies run services between Quito, Ecuador and Santiago, Chile?

Avianca - Aerovías del Continente Americano S.A., LATAM Chile and four other airlines fly from Quito to Santiago hourly. Alternatively, you can take a bus from Quito to Santiago via Quito and Rumichaca in around 3 days 7 h.

Airlines
Avianca - Aerovías del Continente Americano S.A.
Website
avianca.com
Flights from Quito to Santiago via Lima
Ave. Duration
6 h 56 min
When
Every day
Estimated price
$350 - $1,000
Flights from Quito to Santiago via Bogota
Ave. Duration
9 h 17 min
When
Every day
Estimated price
$350 - $1,000
Flights from Quito to Santiago via Guayaquil, Bogota
Ave. Duration
11 h 55 min
When
Saturday
Estimated price
$350 - $1,000
LATAM Chile
Website
latam.com
Flights from Quito to Santiago via Lima
Ave. Duration
7 h 36 min
When
Every day
Estimated price
$360 - $1,800
Flights from Quito to Santiago via Lima, Antofagasta
Ave. Duration
10 h 44 min
When
Wednesday
Estimated price
$360 - $1,800
Copa Airlines
Website
copaair.com
Flights from Quito to Santiago via Panama City
Ave. Duration
11 h 32 min
When
Every day
Estimated price
$380 - $1,400
Gol Transportes Aéreos
Website
voegol.com.br
Flights from Quito to Santiago via Sao Paulo
Ave. Duration
11 h 55 min
When
Tuesday, Thursday and Sunday
Estimated price
$460 - $1,400
Bus operators
Skybus
Phone
+58 414 8448807
Website
facebook.com
Bus from Quito to Rumichaca, Ecuador
Ave. Duration
5 h
Frequency
Every 2 hours
Schedules at
facebook.com
Bus from Quito to Santiago
Ave. Duration
3 days 8 h
Frequency
Once daily
Estimated price
$400
Schedules at
facebook.com
Linea de Los Andes
Phone
+57 (2) 641 0936 Colombia / +58 (424) 7017720 / (276) 415 78 01 Venezuela / (212) 762 94 06 Caracas
Email
reservascali@lineasdelosandes.com.co
Website
lineasdelosandes.com.co
Bus from Quito to Rumichaca
Ave. Duration
5 h
Frequency
Every 3 hours
Estimated price
$70 - $95
Schedules at
lineasdelosandes.com.co
Bus from Rumichaca to Santiago
Ave. Duration
3 days 1 h
Frequency
Twice daily
Estimated price
$310 - $550
Schedules at
lineasdelosandes.com.co
Tiseca
Phone
+58 276 7713091
Website
tiseca.com.ve
Bus from Quito to Rumichaca
Ave. Duration
6 h
Frequency
Hourly
Schedules at
tiseca.com.ve
Conexiones Siglo 21
Phone
+57 311 357 5623
Email
ayuda@conexionesiglo21.com
Website
conexionesiglo21.com
Bus from Quito to Ipiales
Ave. Duration
5 h
Frequency
3 times a day
Schedules at
conexionesiglo21.com
Alianza Internacional del Sur
Website
facebook.com
Bus from Quito to Rumichaca
Ave. Duration
5 h
Frequency
Once daily
Schedules at
venezuelatravelinternational.com
Book at
venezuelatravelinternational.com

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How to get from Southend Airport into central London, How to get from London to Edinburgh and How do I get from Sydney to Melbourne - to help you get the most out of your next trip.

More Questions & Answers

Santiago is 2 h ahead of Quito. It is currently 10:00 AM in Quito and 12:00 PM in Santiago.

Yes, the driving distance between Quito to Santiago is 5172 km. It takes approximately 2 days 19 h to drive from Quito to Santiago.

Get driving directions

Gol Transportes Aéreos, Copa Airlines, LATAM Chile and Avianca - Aerovías del Continente Americano S.A. offer flights from Quito Airport to Santiago Airport.

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There are 2187+ hotels available in Santiago. Prices start at $44 USD per night.

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The best way to get from Quito to Quito Airport is to taxi which takes 37 min and costs $30 - $40.

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