German Railways (DB) operates a train from Quedlinburg to Berlin hourly. Tickets cost $24 - $35 and the journey takes 1 h 11 min. German Railways (DB) also services this route hourly. Alternatively, FlixBus operates a bus from Quedlinburg to Berlin twice daily. Tickets cost $13 - $23 and the journey takes 2 h 55 min. 2 other operators also service this route.
From Quedlinburg train to Magdeburg Hbf then train to Berlin Alexanderplatz. 3 h 31 min 52€. From Quedlinburg bus to Berlin, Masurenallee/ZOB, bus to S+U Zoologischer Garten Bhf, then line 100 bus to Berlin, S+U Alexanderplatz Bhf/Memhardstr.. 3 h 47 min 23€. From Quedlinburg drive to Berlin. 2 h 19 min 31€.