Rome2Rio

How to get fromPython (Busch Gardens Tampa Bay) to Key Westby bus, plane, shuttle, ferry, car, train or bus (Flixbus, Greyhound)

Find Transport to Key West

See all options

There are 8 ways to get from Python (Busch Gardens Tampa Bay) to Key West by bus, plane, shuttle, ferry, car, train, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 32 bus to Tampa, fly

    best
    1. Take the bus from Netpark Transfer Center to Airport Rental Car Facilitybus
    2. Fly from Tampa (TPA) to Key West International Airport (EYW)planeTPA - EYW
    4h 18m
    $125–507

  2. Bus

    cheapest
    1. Take the bus from Tampa Bus Station to Miami Airport Stationbus
    2. Take the bus from Miami Airport Station to Big Pine Keybus
    3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    15h 12m
    $55–95

  3. Bus, shuttle

    1. Take the bus from University of South Florida Tampa to Miami AirportbusTampa / ...
    2. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttleTo the Keys
    12h 54m
    $182–294

  4. Bus, ferry

    1. Take the bus from Tampa Bus Station to Fort Myers Bus StopbusFlixBus 2421
    2. Take the ferry from Fort Myers Beach, FL to Key West, FLferryFort Myers Beach
    12h 56m
    $160–176

  5. Drive 397.5 mi

    1. Drive from Python (Busch Gardens Tampa Bay) to Key Westcar397.5 mi
    8h 2m
    $73–105

  6. Line 12 bus, line 300 bus to Saint Petersburg–Clearwater International Airport, fly

    1. Take the bus from 22nd St @ 97th Av to Marion Transit Centerbus
    2. Take the bus from Marion Transit Parking Lot to Psta 34Th St Layby - Platform - Bbus
    3. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)planePIE - EYW
    5h 46m
    $69–211

  7. Drive to Orlando Sanford, fly

    1. Drive from Python (Busch Gardens Tampa Bay) to Orlando Sanford (SFB)car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)planeSFB - EYW
    3h 16m
    $85–541

  8. Train, bus

    1. Take the train from Tampa to Delray Beach Amtraktrain
    2. Take the train from Delray Beach Station to Miami Airport Stationtrain
    3. Take the bus from Miami Airport Station to Big Pine Keybus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    14h 43m
    $60–154

Python (Busch Gardens Tampa Bay) to Key West by foot, bus, and train

Calendar7Weekly Services
Duration14h 43mAverage Duration
Ticket$60Cheapest Price
See schedules

Questions & Answers

What companies run services between Python (Busch Gardens Tampa Bay), FL, USA and Key West, FL, USA?

You can take a vehicle from Python (Busch Gardens Tampa Bay) to N Roosevelt & 3rd Street via 22nd St @ 97th Av, Marion Transit Center, Tampa Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 15h 12m.

Airlines
Train operators
Bus operators
Ferry operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Python (Busch Gardens Tampa Bay)

Trips to Key West

Popular routes