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There are 7 ways to get from Puno to Santiago by bus, plane or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus to Juliaca, fly  •  9 h 52 min

  1. Take the bus from Puno to Juliaca
  2. Fly from Juliaca (JUL) to Santiago (SCL) JUL - SCL

$189 - $300

Cheapest option

Bus Expreso Norte  •  38 h 24 min

  1. Take the bus from Puno to Tacna
  2. Take the bus from Tacna to Arica
  3. Take the bus from Arica to Santiago - San Borja

$48 - $93

5 alternative options

Bus, bus to Arica, fly  •  14 h 9 min

  1. Take the bus from Puno to Tacna
  2. Take the bus from Tacna to Arica
  3. Fly from Arica (ARI) to Santiago (SCL) ARI - SCL

$129 - $474

Bus, bus to La Paz, fly  •  13 h 51 min

  1. Take the bus from Puno to Desaguadero
  2. Take the bus from Desaguadero to La Paz - Cementerio y Plaza Tomas Katari
  3. Fly from La Paz (LPB) to Santiago (SCL) LPB - SCL

$194 - $1,099

Bus Omega  •  32 h

  1. Take the bus from Puno to Tacna Via Tacna
  2. Take the bus from Tacna to Santiago Via Cucuta / ...

$95 - $130

Bus Skybus  •  36 h 34 min

  1. Take the bus from Puno to Arequipa Puno / ...
  2. Take the bus from Arequipa to Santiago Via Cucuta

Drive  •  30 h 45 min

  1. Drive from Puno to Santiago 1565.7 miles

$250 - $380

Questions & Answers

The cheapest way to get from Puno to Santiago is to bus which costs $45 - $95 and takes 38 h 24 min.

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The quickest way to get from Puno to Santiago is to bus and fly which costs $180 - $300 and takes 9 h 52 min.

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No, there is no direct bus from Puno to Santiago. However, there are services departing from Puno and arriving at Santiago via Tacna. The journey, including transfers, takes approximately 32 h.

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The distance between Puno and Santiago is 1960 km. The road distance is 2505.1 km.

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The best way to get from Puno to Santiago without a car is to bus which takes 32 h and costs $95 - $130.

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It takes approximately 9 h 52 min to get from Puno to Santiago, including transfers.

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Puno to Santiago bus services, operated by Expreso Turismo San Martin Nobleza, depart from Puno station.

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There is no direct flight from Juliaca Airport to Santiago Airport. The quickest flight takes 6 h 4 min and has one stopover.

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Puno to Santiago bus services, operated by Omega, arrive at Santiago station.

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Santiago is 1 h ahead of Puno. It is currently 7:24 PM in Puno and 9:24 PM in Santiago.

Map of how to get from Puno to Santiago.
Launch map view
  • Distance: 1224.8 miles
  • Duration: 9 h 52 min

What companies run services between Puno, Peru and Santiago, Chile?

You can take a bus from Puno to Santiago via Tacna in around 32 h.

Airlines
LATAM Chile
Website
latam.com
Flights from Juliaca to Santiago via Lima
Ave. Duration
6 h 25 min
When
Every day
Estimated price
$300 - $400
Flights from Juliaca to Santiago via Cuzco, Lima
Ave. Duration
7 h 58 min
When
Saturday
Estimated price
$300 - $400
Flights from Juliaca to Santiago via Lima, Antofagasta
Ave. Duration
11 h 3 min
When
Sunday
Estimated price
$300 - $400
Flights from Arica to Santiago
Ave. Duration
2 h 30 min
When
Every day
Estimated price
$230 - $1,100
Flights from La Paz to Santiago
Ave. Duration
2 h 57 min
When
Monday, Tuesday, Thursday and Friday
Estimated price
$160 - $900
Sky Airline
Website
skyairline.com
Flights from Arica to Santiago
Ave. Duration
2 h 30 min
When
Every day
Estimated price
$130 - $460
JetSMART
Website
jetsmart.com
Flights from Arica to Santiago
Ave. Duration
2 h 31 min
When
Monday, Wednesday and Sunday
Estimated price
$65 - $360
Flights from Arica to Santiago via Calama
Ave. Duration
4 h 42 min
When
Tuesday
Estimated price
$65 - $370
Avianca - Aerovías del Continente Americano S.A.
Website
avianca.com
Flights from Juliaca to Santiago via Lima
Ave. Duration
10 h 58 min
When
Every day
Estimated price
$180 - $800
Bus operators
Cruz Del Sur
Phone
0801-11111
Website
cruzdelsur.com.pe
Bus from Puno to Juliaca
Ave. Duration
1 h
Frequency
Once daily
Estimated price
$7 - $22
Schedules at
cruzdelsur.com.pe
Book at
cruzdelsur.com.pe
Regular in Advance
$7 - $11
Regular
$13 - $19
VIP
$15 - $22
Bus from Puno to Arequipa
Ave. Duration
5 h 15 min
Frequency
3 times a day
Estimated price
$11 - $35
Schedules at
cruzdelsur.com.pe
Regular in Advance
$11 - $17
Regular
$19 - $26
VIP
$22 - $35
Expreso Turismo San Martin Nobleza
bus
Bus from Tacna to Arica
Ave. Duration
1 h
Frequency
Every 30 minutes
Estimated price
$3
Omega
Phone
+57 1 8000 18 1670
Email
atencionalcliente@omega.com.co
Website
omega.com.co
Bus from Tacna to Arica
Ave. Duration
1 h
Frequency
3 times a day
Estimated price
$6 - $9
Schedules at
omega.com.co
Bus from Tacna to Santiago
Ave. Duration
23 h
Frequency
Twice daily
Estimated price
$95 - $130
Schedules at
omega.com.co
Tour Peru
Phone
951677194
Email
reservas@tourperu.com.pe
Website
tourperu.com.pe
Bus from Puno to Desaguadero
Ave. Duration
4 h 38 min
Frequency
Twice daily
Schedules at
ticketsbolivia.com.bo
Book at
ticketsbolivia.com.bo
Transporte Union Ingavi
Phone
+591 2 2380472
Bus from Desaguadero to La Paz - Cementerio y Plaza Tomas Katari
Ave. Duration
2 h 30 min
Frequency
Every 4 hours
Estimated price
$3
Skybus
Phone
+58 414 8448807
Website
facebook.com
Bus from Tacna to Santiago
Ave. Duration
23 h
Frequency
Once daily
Schedules at
facebook.com
Bus from Arequipa to Santiago
Ave. Duration
30 h
Frequency
Once daily
Schedules at
facebook.com
Alianza Internacional del Sur
Website
facebook.com
Bus from Tacna to Santiago
Ave. Duration
23 h
Frequency
Twice a week
Schedules at
venezuelatravelinternational.com
Book at
venezuelatravelinternational.com
Transzela
Peru Hop
Phone
+51 1 2422140
Email
info@peruhop.com
Bus from Puno to Arequipa
Ave. Duration
8 h
Frequency
5 times a day
Estimated price
$50 - $70
Schedules at
peruhop.com
Book at
peruhop.com
CIVA
Website
civa.com.pe
Bus from Puno to Arequipa
Ave. Duration
5 h 30 min
Frequency
Once daily
Estimated price
$8 - $35
Schedules at
civa.com.pe
Regular Semi Bed
$19 - $27
Regular Bed
$24 - $35
Economy
$8 - $12
Premium Semi Bed
$19 - $26
Premium Bed
$24 - $35
Peru Tour Bus
Phone
0051 84 632307
Email
reservas@perutourbus.com
Website
perutourbus.com
Bus from Puno to Arequipa
Ave. Duration
6 h
Frequency
Once daily
Schedules at
perutourbus.com
Book at
perutourbus.com
Expreso Norte
Fichtur VIP
Phone
+56 (02) 7205232
Website
fichtur.cl
Bus from Arica to Santiago
Ave. Duration
27 h 20 min
Frequency
3 times a day
Estimated price
$50
Schedules at
viajaenbus.cl
Pullman Bus
Phone
600 320 3200
Website
pullman.cl
Bus from Arica to Santiago
Ave. Duration
26 h 20 min
Frequency
Twice daily
Estimated price
$65 - $90
Schedules at
pullman.cl

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More Questions & Answers

Yes, the driving distance between Puno to Santiago is 2505 km. It takes approximately 30 h 45 min to drive from Puno to Santiago.

Get driving directions

Avianca - Aerovías del Continente Americano S.A. and LATAM Chile offer flights from Juliaca Airport to Santiago Airport.

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There are 2208+ hotels available in Santiago. Prices start at $45 USD per night.

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