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There are 5 ways to get from Puno to Santa Cruz de la Sierra by bus, plane, bus and ferry or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus, fly  •  8 h 8 min

  1. Take the bus from Puno to Desaguadero
  2. Take the bus from Desaguadero to La Paz - Cementerio y Plaza Tomas Katari
  3. Fly from La Paz (LPB) to Santa Cruz (VVI) LPB - VVI

$100 - $195

Cheapest option

Bus via Desaguadero  •  20 h 51 min

  1. Take the bus from Puno to Desaguadero
  2. Take the bus from Desaguadero to La Paz - Cementerio y Plaza Tomas Katari
  3. Take the bus from La Paz to Santa Cruz de la Sierra - Terminal bimodal

$27 - $64

3 alternative options

Bus  •  28 h 55 min

  1. Take the bus from Puno to La Paz Puno / ...
  2. Take the bus from La Paz to Santa Cruz de la Sierra - Terminal bimodal La Paz

$27 - $61

Tour, bus  •  29 h 52 min

  1. Take the Tour from Puno to La Paz
  2. Take the bus from La Paz to Cochabamba
  3. Take the bus from Cochabamba to Santa Cruz de la Sierra - Terminal Bimodal

$308 - $327

Drive  •  16 h 50 min

  1. Drive from Puno to Santa Cruz de la Sierra 699 miles

$100 - $150

Questions & Answers

The cheapest way to get from Puno to Santa Cruz de la Sierra is to bus which costs $26 - $65 and takes 28 h 55 min.

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The quickest way to get from Puno to Santa Cruz de la Sierra is to bus and fly which costs $95 - $200 and takes 8 h 8 min.

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No, there is no direct bus from Puno to Santa Cruz de la Sierra. However, there are services departing from Puno and arriving at Santa Cruz de la Sierra - Terminal bimodal via La Paz. The journey, including transfers, takes approximately 28 h 55 min.

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The distance between Puno and Santa Cruz de la Sierra is 759 km. The road distance is 1118.5 km.

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The best way to get from Puno to Santa Cruz de la Sierra without a car is to bus which takes 20 h 51 min and costs $26 - $65.

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It takes approximately 8 h 8 min to get from Puno to Santa Cruz de la Sierra, including transfers.

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Puno to Santa Cruz de la Sierra bus services, operated by Titicaca Bolivia, depart from Puno station.

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The quickest flight from La Paz Airport to Santa Cruz Airport is the direct flight which takes 1 h.

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Puno to Santa Cruz de la Sierra bus services, operated by Trans Copacabana SA, arrive at Santa Cruz de la Sierra - Terminal bimodal station.

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Santa Cruz de la Sierra is 1 h ahead of Puno. It is currently 12:56 AM in Puno and 1:56 AM in Santa Cruz de la Sierra.

Map of how to get from Puno to Santa Cruz de la Sierra.
Launch map view
  • Distance: 474.5 miles
  • Duration: 8 h 8 min

What companies run services between Puno, Peru and Santa Cruz de la Sierra, Bolivia?

You can take a bus from Puno to Santa Cruz de la Sierra via Desaguadero, La Paz - Cementerio y Plaza Tomas Katari, Cementerio / Ajayuni, Central / Taypi Uta, and La Paz in around 20 h 51 min.

Airlines
Boliviana de Aviación
Website
boa.bo
Flights from La Paz to Santa Cruz
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$65 - $160
Flights from La Paz to Santa Cruz via Cochabamba
Ave. Duration
2 h 1 min
When
Tuesday, Thursday and Sunday
Estimated price
$65 - $160
Amaszonas
Website
amaszonas.com
Flights from La Paz to Santa Cruz
Ave. Duration
1 h
When
Every day
Estimated price
$65 - $180
Bus operators
Transporte Union Ingavi
Phone
+591 2 2380472
Bus from Desaguadero to La Paz - Cementerio y Plaza Tomas Katari
Ave. Duration
2 h 30 min
Frequency
Every 4 hours
Estimated price
$3
Trans Copacabana SA
Phone
Cochabamba: +(591)44591818, +(591)72244625
Email
info@transcopacabanasa.com.bo
Website
transcopacabanasa.com.bo
Bus from La Paz to Santa Cruz de la Sierra - Terminal bimodal
Ave. Duration
14 h
Frequency
3 times a day
Estimated price
$13 - $35
Schedules at
transcopacabanasa.com.bo
Book at
ticketsbolivia.com.bo
3rd Class
$13 - $18
2nd Class
$19 - $27
Bus from La Paz to Cochabamba
Ave. Duration
8 h
Frequency
Every 4 hours
Estimated price
$7 - $13
Schedules at
transcopacabanasa.com.bo
Book at
ticketsbolivia.com.bo
3rd Class
$7 - $10
2nd Class
$9 - $13
Bus from Cochabamba to Santa Cruz de la Sierra - Terminal Bimodal
Ave. Duration
10 h
Frequency
4 times a day
Estimated price
$8 - $19
Schedules at
transcopacabanasa.com.bo
Book at
ticketsbolivia.com.bo
3rd Class
$8 - $12
2nd Class
$12 - $17
Copacabana 1 MEM
Peru Hop
Phone
+51 1 2422140
Email
info@peruhop.com
Bus from Puno to La Paz
Ave. Duration
13 h
Frequency
Twice daily
Estimated price
$30 - $45
Schedules at
peruhop.com
Book at
peruhop.com
Tour Peru
Phone
951677194
Email
reservas@tourperu.com.pe
Website
tourperu.com.pe
Bus from Puno to La Paz
Ave. Duration
7 h 15 min
Frequency
Once daily
Schedules at
ticketsbolivia.com.bo
Book at
ticketsbolivia.com.bo
Rumbo Explora
Phone
+51 989 643208
Email
rumboexplora@gmail.com
Website
titicaca.cruises
Bus and ferry from Puno to La Paz
Ave. Duration
12 h 30 min
Frequency
Once daily
Estimated price
$293
Schedules at
titicaca.cruises
Book at
titicaca.cruises
Flota Bolivar
Phone
+591 2 2281973 La Paz / 4 4221819 Cochabamba / 3 3625458 Santa Cruz / 4 6453849 Sucre / 4 6830856 Yacuiba
Website
facebook.com
Bus from La Paz to Cochabamba
Ave. Duration
8 h
Frequency
Hourly
Estimated price
$7 - $15
Schedules at
facebook.com
Bus from Cochabamba to Santa Cruz de la Sierra
Ave. Duration
10 h
Frequency
Every 4 hours
Estimated price
$13 - $19
Schedules at
facebook.com
Cosmos
Phone
+(591) 2 2281938 / Potosí: +(591)2-6245831
Bus from La Paz to Cochabamba
Ave. Duration
8 h
Frequency
Hourly
Estimated price
$8
Schedules at
mi.lapaz.bo
Bus from Cochabamba to Santa Cruz de la Sierra
Ave. Duration
10 h
Frequency
5 times a day
Estimated price
$19
Schedules at
sites.google.com
Transportes El Dorado
Phone
Potosí: +(591)2-6243343, +(591)-22281672
Website
facebook.com
Bus from La Paz to Cochabamba
Ave. Duration
8 h
Frequency
Hourly
Estimated price
$8
Schedules at
sites.google.com
Bus from Cochabamba to Santa Cruz de la Sierra
Ave. Duration
10 h
Frequency
5 times a day
Estimated price
$19
Schedules at
sites.google.com
Transporte Jumbo Bus Bolivia
Phone
+591 2 2281832 / 2281726
Bus from La Paz to Cochabamba
Ave. Duration
8 h
Frequency
Every 4 hours
Estimated price
$8
Schedules at
sites.google.com
Transporte Interdepartamental 6 de agosto
Phone
+(591)71520995
Bus from La Paz to Cochabamba
Ave. Duration
7 h 30 min
Frequency
5 times a day
Estimated price
$21
Schedules at
andestransit.com
Cisne Tours
Phone
+591 2 2281937
Bus from La Paz to Cochabamba
Ave. Duration
8 h
Frequency
4 times a day
Estimated price
$8
Schedules at
sites.google.com
Nobleza
Phone
+591 4 4551499 Cochabamba /
Bus from La Paz to Cochabamba
Ave. Duration
8 h
Frequency
4 times a day
Estimated price
$8
Schedules at
sites.google.com
Bus from Cochabamba to Santa Cruz
Ave. Duration
10 h
Frequency
4 times a day
Estimated price
$19
Schedules at
sites.google.com
Expreso Mopar
Phone
+591 3 3323001 / 2 2282154
Bus from La Paz to Cochabamba
Ave. Duration
8 h
Frequency
3 times a day
Estimated price
$8
Schedules at
sites.google.com
Bus from Cochabamba to Santa Cruz de la Sierra
Ave. Duration
9 h 45 min
Frequency
3 times a day
Estimated price
$10
Schedules at
sites.google.com
Trans Alteño
Phone
+(591)4234600 - 4258600
Email
info@terbuscbbasa.com.bo
Bus from La Paz to Cochabamba
Ave. Duration
8 h
Frequency
3 times a day
Estimated price
$8
Schedules at
sites.google.com
Trans Crucero
Phone
+593 76973424
Bus from La Paz to Cochabamba
Ave. Duration
8 h
Frequency
3 times a day
Estimated price
$8
Schedules at
mi.lapaz.bo
Expreso Cochabamba
Phone
Potosí: +(591)-26243362
Website
es-es.facebook.com
Bus from La Paz to Cochabamba
Ave. Duration
6 h 5 min
Frequency
Twice daily
Estimated price
$21
Schedules at
facebook.com
Trans Carrasco
Phone
+591 60362456 Cochabamba / 4 4225457 Cochabamba / 71490343 Sucre
Email
jose_eddyporsiempre@hotmail.com
Website
facebook.com
Bus from Cochabamba to Santa Cruz de la Sierra - Terminal Bimodal
Ave. Duration
9 h
Frequency
Every 4 hours
Estimated price
$9 - $11
Schedules at
facebook.com
Flota Unificado
Website
facebook.com
Bus from Cochabamba to Santa Cruz de la Sierra
Ave. Duration
10 h
Frequency
Every 4 hours
Estimated price
$19
Schedules at
sites.google.com
Linea De Omnibuses Expreso Santa Cruz De La Sierra S.R.L.
Phone
+591-3-3471459
Bus from Cochabamba to Santa Cruz de la Sierra - Terminal Bimodal
Ave. Duration
10 h
Frequency
Every 4 hours
Estimated price
$19
Schedules at
sites.google.com

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More Questions & Answers

Yes, the driving distance between Puno to Santa Cruz de la Sierra is 1118 km. It takes approximately 16 h 50 min to drive from Puno to Santa Cruz de la Sierra.

Get driving directions

Amaszonas and Boliviana de Aviación offer flights from La Paz Airport to Santa Cruz Airport.

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There are 238+ hotels available in Santa Cruz de la Sierra. Prices start at $25 USD per night.

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