There are 4 ways to get from Puno to Santa Cruz de la Sierra by bus, bus and ferry, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  25 h 40 min

  1. Take the bus from Puno to La Paz Direct service / ...
  2. Take the bus from La Paz to Santa Cruz de la Sierra La Paz

$26 - $61

3 alternative options

Tour, bus  •  30 h 35 min

  1. Take the Tour from Puno to La Paz
  2. Take the bus from La Paz to Cochabamba
  3. Take the bus from Cochabamba to Santa Cruz de la Sierra

$333

Drive  •  16 h 50 min

  1. Drive from Puno to Santa Cruz de la Sierra 699 miles

$100 - $150

Bus, fly  •  9 h 39 min

  1. Take the bus from Puno to La Paz
  2. Fly from La Paz (LPB) to Santa Cruz (VVI) LPB - VVI

$102 - $195

Questions & Answers

The cheapest way to get from Puno to Santa Cruz de la Sierra is to bus which costs $25 - $65 and takes 25 h 40 min.

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The quickest way to get from Puno to Santa Cruz de la Sierra is to bus and fly which costs $100 - $200 and takes 9 h 39 min.

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No, there is no direct bus from Puno to Santa Cruz de la Sierra. However, there are services departing from Puno and arriving at Santa Cruz de la Sierra via La Paz. The journey, including transfers, takes approximately 25 h 40 min.

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The distance between Puno and Santa Cruz de la Sierra is 759 km. The road distance is 1118.5 km.

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The best way to get from Puno to Santa Cruz de la Sierra without a car is to bus which takes 25 h 40 min and costs $25 - $65.

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It takes approximately 25 h 40 min to get from Puno to Santa Cruz de la Sierra, including transfers.

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Puno to Santa Cruz de la Sierra bus services, operated by Titicaca Bolivia, depart from Puno station.

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The quickest flight from La Paz Airport to Santa Cruz Airport is the direct flight which takes 1 h.

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Puno to Santa Cruz de la Sierra bus services, operated by Copacabana 1 MEM, arrive at Santa Cruz de la Sierra station.

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Santa Cruz de la Sierra is 1 h ahead of Puno. It is currently 6:08 AM in Puno and 7:08 AM in Santa Cruz de la Sierra.

Yes, the driving distance between Puno to Santa Cruz de la Sierra is 1118 km. It takes approximately 16 h 50 min to drive from Puno to Santa Cruz de la Sierra.

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Boliviana de Aviación and Amaszonas offer flights from La Paz Airport to Santa Cruz Airport.

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Map of how to get from Puno to Santa Cruz de la Sierra.
Launch map view
  • Distance: 474.5 miles
  • Duration: 25 h 40 min

What companies run services between Puno, Peru and Santa Cruz de la Sierra, Bolivia?

You can take a bus from Puno to Santa Cruz de la Sierra via La Paz in around 25 h 40 min.

Airlines
Amaszonas
Website
amaszonas.com
Flights from La Paz to Santa Cruz
Ave. Duration
1 h
When
Every day
Estimated price
$65 - $180
Boliviana de Aviación
Website
boa.bo
Flights from La Paz to Santa Cruz
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$65 - $160
Bus operators
Copacabana 1 MEM
Phone
+591 2 2282135 /2 2282368 /4 4250226 /4 4361441
Website
facebook.com
Bus from La Paz to Santa Cruz de la Sierra
Ave. Duration
18 h
Frequency
3 times a day
Estimated price
$32
Schedules at
ticketsbolivia.com.bo
Cosmos
Phone
+(591) 2 2281938 / Potosí: +(591)2-6245831
Bus from La Paz to Santa Cruz de la Sierra - Terminal Bimodal
Ave. Duration
18 h
Frequency
3 times a day
Estimated price
$32
Schedules at
mi.lapaz.bo
Flota Bolivar
Phone
+591 2 2281973 La Paz / 4 4221819 Cochabamba / 3 3625458 Santa Cruz / 4 6453849 Sucre / 4 6830856 Yacuiba
Website
facebook.com
Bus from La Paz Bus Terminal to Santa Cruz de la Sierra - Terminal Bimodal
Ave. Duration
18 h
Frequency
3 times a day
Estimated price
$23 - $35
Schedules at
facebook.com
Trans Copacabana SA
Website
transcopacabanasa.com.bo
Bus from La Paz to Santa Cruz de la Sierra - Terminal bimodal
Ave. Duration
18 h
Frequency
3 times a day
Estimated price
$13 - $35
Schedules at
transcopacabanasa.com.bo
Book at
transcopacabanasa.com.bo
3rd Class
$13 - $18
2nd Class
$19 - $26
Transportes El Dorado
Phone
Potosí: +(591)2-6243343, +(591)-22281672
Website
facebook.com
Bus from La Paz to Santa Cruz de la Sierra - Terminal bimodal
Ave. Duration
18 h
Frequency
3 times a day
Estimated price
$32
Schedules at
mi.lapaz.bo
Expreso Mopar
Phone
+591 3 3323001 / 2 2282154
Bus from La Paz to Santa Cruz de la Sierra
Ave. Duration
18 h 5 min
Frequency
Twice daily
Estimated price
$62
Schedules at
sites.google.com
Trans Crucero
Phone
+593 76973424
Bus from La Paz to Santa Cruz de la Sierra - Terminal bimodal
Ave. Duration
18 h
Frequency
Once daily
Estimated price
$32
Schedules at
mi.lapaz.bo
Rumbo Explora
Phone
+51 989 643208
Email
rumboexplora@gmail.com
Website
titicaca.cruises
Bus and ferry from Puno to La Paz
Ave. Duration
12 h 30 min
Frequency
Once daily
Estimated price
$293
Schedules at
titicaca.cruises
Book at
titicaca.cruises
Expreso Cochabamba
Phone
Potosí: +(591)-26243362
Website
es-es.facebook.com
Bus from La Paz to Cochabamba
Ave. Duration
6 h 5 min
Frequency
Twice daily
Estimated price
$21
Schedules at
facebook.com
Transporte Interdepartamental 6 de agosto
Phone
+(591)71520995
Bus from La Paz to Cochabamba
Ave. Duration
6 h 5 min
Frequency
Twice daily
Estimated price
$21
Schedules at
andestransit.com
Trans Alteño
Phone
+(591)4234600 - 4258600
Email
info@terbuscbbasa.com.bo
Bus from Cochabamba to Santa Cruz de la Sierra
Ave. Duration
10 h
Frequency
Twice daily
Estimated price
$19
Schedules at
sites.google.com
Flota Punata
Phone
+59144256955
Website
es-la.facebook.com
Bus from Cochabamba to Santa Cruz de la Sierra
Ave. Duration
10 h
Frequency
Once daily
Schedules at
sites.google.com

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