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There are 3 ways to get from Puerto Rico to Santiago de Cuba by plane or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Holguin, train  •  8 h 58 min

  1. Fly from San Juan (SJU) to Holguin (HOG) SJU - HOG
  2. Take the train from Cacocum to Santiago de Cuba

$336 - $1,376

Cheapest option

Fly to Camaguey, train  •  13 h 1 min

  1. Fly from San Juan (SJU) to Camaguey (CMW) SJU - CMW
  2. Take the train from Camaguey to Santiago de Cuba

$296 - $976

1 alternative option

Fly to Santiago  •  4 h 25 min

  1. Fly from San Juan (SJU) to Santiago (SCU) SJU - SCU

$650 - $1,500

Questions & Answers

The cheapest way to get from Puerto Rico to Santiago de Cuba is to fly and train which costs $290 - $1,000 and takes 13 h 1 min.

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The quickest way to get from Puerto Rico to Santiago de Cuba is to fly which costs $650 - $1,500 and takes 4 h 25 min.

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The distance between Puerto Rico and Santiago de Cuba is 999 km.

It takes approximately 8 h 58 min to get from Puerto Rico to Santiago de Cuba, including transfers.

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There is no direct flight from San Juan Airport to Holguin Airport. The quickest flight takes 5 h 35 min and has one stopover.

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Santiago de Cuba is 1 h behind Puerto Rico. It is currently 3:36 AM in Puerto Rico and 2:36 AM in Santiago de Cuba.

American Airlines, Copa Airlines and JetBlue Airways offer flights from San Juan Airport to Holguin Airport.

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There are 134+ hotels available in Santiago de Cuba. Prices start at $25 USD per night.

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The best way to get from Puerto Rico to San Juan Airport is to drive which takes 11 min and costs .

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Map of how to get from Puerto Rico to Santiago de Cuba.
Launch map view
  • Distance: 624.5 miles
  • Duration: 8 h 58 min

What companies run services between Puerto Rico and Santiago de Cuba?

JetBlue Airways and Cubana de Aviación fly from Carolina to Santiago de Cuba 3 times a week.

Airlines
American Airlines
Website
aa.com
Flights from San Juan to Holguin via Miami
Ave. Duration
5 h 35 min
When
Every day
Estimated price
$270 - $1,800
Flights from San Juan to Camaguey via Miami
Ave. Duration
8 h 9 min
When
Every day
Estimated price
$260 - $1,700
Flights from San Juan to Camaguey via Christiansted, Miami
Ave. Duration
10 h 10 min
When
Monday, Tuesday, Friday, Saturday and Sunday
Estimated price
$280 - $1,800
JetBlue Airways
Website
jetblue.com
Flights from San Juan to Holguin via Fort Lauderdale
Ave. Duration
10 h 48 min
When
Every day
Estimated price
$320 - $1,400
Flights from San Juan to Camaguey via Fort Lauderdale
Ave. Duration
8 h 12 min
When
Every day
Estimated price
$290 - $1,200
Cubana de Aviación
Website
cubana.cu
Flights from San Juan to Santiago via Santo Domingo
Ave. Duration
5 h 48 min
When
Tuesday and Friday
Estimated price
$650 - $1,500
Copa Airlines
Website
copaair.com
Flights from San Juan to Holguin via Panama City
Ave. Duration
6 h 25 min
When
Wednesday and Saturday
Estimated price
$450 - $1,700
Train operators
Ferrocarriles de Cuba
Website
en.wikipedia.org
Train from Cacocum to Santiago de Cuba
Ave. Duration
2 h 35 min
Frequency
On demand
Estimated price
$7 - $11
Schedules at
seat61.com
Train from Camaguey to Santiago de Cuba
Ave. Duration
6 h 15 min
Frequency
On demand
Estimated price
$16 - $30
Schedules at
seat61.com

Want to know more about travelling around Cuba

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.