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There are 6 ways to get from Puerto Iguazú to Santa Cruz de la Sierra by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  5 h 27 min

  1. Fly from Ciudad del Este (AGT) to Santa Cruz (VVI) AGT - VVI

$225 - $720

Cheapest option

Bus via Caaguazu  •  27 h 25 min

  1. Take the bus from Ciudad del Este, Paraguay to Caaguazu
  2. Take the bus from Caaguazu to Coronel Oviedo
  3. Take the bus from Coronel Oviedo to Asunción
  4. Take the bus from Asunción to Santa Cruz de la Sierra

$54 - $64

4 alternative options

Bus  •  26 h 58 min

  1. Take the bus from Ciudad del Este to Asunción Ciudad del Este / ...
  2. Take the bus from Asunción to Santa Cruz de la Sierra Asunción / ...

$63 - $73

Bus via Foz do Iguaçu  •  28 h 2 min

  1. Take the bus from Foz do Iguaçu to Asunción
  2. Take the bus from Asunción to Santa Cruz de la Sierra Asunción / ...

$72 - $90

Bus via Villarrica  •  32 h 49 min

  1. Take the bus from Ciudad del Este to Villarrica
  2. Take the bus from Villarrica to Asunción
  3. Take the bus from Asunción to Santa Cruz de la Sierra

$66 - $89

Drive  •  24 h 24 min

  1. Drive from Puerto Iguazú to Santa Cruz de la Sierra 1036.7 miles

$75 - $120

Questions & Answers

The cheapest way to get from Puerto Iguazú to Santa Cruz de la Sierra is to bus which costs $1900 - $2400 and takes 27 h 25 min.

More details

The quickest way to get from Puerto Iguazú to Santa Cruz de la Sierra is to fly which costs $8000 - $27000 and takes 5 h 27 min.

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No, there is no direct bus from Puerto Iguazú to Santa Cruz de la Sierra. However, there are services departing from Puerto Iguazú and arriving at Santa Cruz de la Sierra via Foz do Iguaçu and Asunción. The journey, including transfers, takes approximately 28 h 2 min.

More details

The distance between Puerto Iguazú and Santa Cruz de la Sierra is 1243 km. The road distance is 1658.7 km.

Get driving directions

The best way to get from Puerto Iguazú to Santa Cruz de la Sierra without a car is to bus which takes 28 h 2 min and costs $2600 - $3300.

More details

It takes approximately 5 h 27 min to get from Puerto Iguazú to Santa Cruz de la Sierra, including transfers.

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Puerto Iguazú to Santa Cruz de la Sierra bus services, operated by Une Sul, depart from Foz do Iguaçu station.

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The best way to get from Puerto Iguazú to Santa Cruz de la Sierra is to fly which takes 5 h 27 min and costs $8000 - $27000. Alternatively, you can bus, which costs $2200 - $2700 and takes 26 h 58 min.

Mode details

There is no direct flight from Ciudad del Este Airport to Santa Cruz Airport. The quickest flight takes 4 h 5 min and has one stopover.

Search flights

Puerto Iguazú to Santa Cruz de la Sierra bus services, operated by Pycasu SA, arrive at Santa Cruz de la Sierra station.

More details

Map of how to get from Puerto Iguazú to Santa Cruz de la Sierra.
Launch map view
  • Distance: 777.1 miles
  • Duration: 5 h 27 min

What companies run services between Puerto Iguazú, Argentina and Santa Cruz de la Sierra, Bolivia?

Amaszonas flies from Puerto Iguazú to Santa Cruz de la Sierra 6 times a week. Alternatively, you can take a bus from Puerto Iguazú to Santa Cruz de la Sierra via Ciudad del Este and Asunción in around 26 h 58 min.

Airlines
Amaszonas
Website
amaszonas.com
Flights from Ciudad del Este to Santa Cruz via Asuncion
Ave. Duration
4 h 5 min
When
Monday to Saturday
Estimated price
$270 - $750
Bus operators
NSA
Phone
+595 21 289 1000
Email
info@nsa.com.py
Website
nsa.com.py
Bus from Ciudad del Este to Asunción
Ave. Duration
6 h
Frequency
Once daily
Estimated price
$14 - $20
Schedules at
nsa.com.py
Convencional
$14 - $20
Une Sul
Phone
55 54 4020 9928
Email
sac@unesul.com
Website
unesul.com.br
Bus from Ciudad del Este to Asunción
Ave. Duration
4 h 1 min
Frequency
Once a week
Book at
unesul.com.br
Bus from Coronel Oviedo to Asunción
Ave. Duration
1 h 31 min
Frequency
Once a week
Book at
unesul.com.br
Bus from Foz do Iguaçu to Asunción
Ave. Duration
6 h 1 min
Frequency
Once a week
Book at
unesul.com.br
Pycasu SA
Phone
+(595) 21.557700
Email
pycasu_sa@pycasu.com.py
Website
pycasu.com.py
Bus from Asunción to Santa Cruz de la Sierra
Ave. Duration
19 h 30 min
Frequency
Once daily
Estimated price
$50 - $60
Schedules at
pycasu.com.py
Yacyretá
Phone
+595 985 330079, Asunción: +595 (21) 551725
Email
yacyreta_sa@hotmail.com
Website
facebook.com
Bus from Asunción to Santa Cruz de la Sierra
Ave. Duration
21 h
Frequency
Once daily
Estimated price
$59
Schedules at
bienvenidoaparaguay.com
Transporte San Luis
Phone
+595.21.551705
Bus from Ciudad del Este, Paraguay to Caaguazu
Ave. Duration
2 h
Frequency
Hourly
Schedules at
bienvenidoaparaguay.com
La Paraguaya Internacional
Phone
+54 11 4314-9044
Bus from Caaguazu to Coronel Oviedo
Ave. Duration
38 min
Frequency
Once daily
Schedules at
busbud.com
Book at
plataforma10.com.ar
La Guaireña
Phone
+595 (21) 551727
Website
bienvenidoaparaguay.com
Bus from Coronel Oviedo to Asunción
Ave. Duration
2 h 24 min
Frequency
Hourly
Estimated price
$4
Schedules at
bienvenidoaparaguay.com
Bus from Villarrica to Asunción
Ave. Duration
2 h 24 min
Frequency
Twice daily
Estimated price
$6
Schedules at
es-la.facebook.com
Gontijo
Phone
0800 728 00 44
Website
clickbus.com.br
Bus from Foz do Iguaçu to Asunción
Ave. Duration
8 h 50 min
Frequency
Once a week
Estimated price
$21 - $29
Schedules at
gontijo.com.br
Book at
comprepassagem.com.br
Convencional
$22 - $29
Executivo
$21 - $27
Ybytyruzú
Phone
+595 (21) 557 310
Bus from Ciudad del Este to Villarrica
Ave. Duration
5 h
Frequency
Hourly
Estimated price
$6
Schedules at
bienvenidoaparaguay.com
Bus from Villarrica to Asunción
Ave. Duration
4 h
Frequency
3 times a day
Estimated price
$4
Schedules at
bienvenidoaparaguay.com
La Yuteña
Phone
+595 (21) 558774
Bus from Villarrica to Asunción
Ave. Duration
2 h 18 min
Frequency
5 times a day
Estimated price
$12
Schedules at
bienvenidoaparaguay.com

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More Questions & Answers

Yes, the driving distance between Puerto Iguazú to Santa Cruz de la Sierra is 1659 km. It takes approximately 24 h 24 min to drive from Puerto Iguazú to Santa Cruz de la Sierra.

Get driving directions

Amaszonas offers flights from Ciudad del Este Airport to Santa Cruz Airport.

Search flights

There are 239+ hotels available in Santa Cruz de la Sierra. Prices start at $26 USD per night.

More details

The best way to get from Puerto Iguazú to Ciudad del Este Airport is to drive which takes 50 min and costs .

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