There are 5 ways to get from Presque Isle to Niagara Falls by plane, bus, bus (Amtrak, Greyhound, Flixbus), train, car, or bus (Amtrak, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, bus
best- Fly from Presque Isle (PQI) to Buffalo Niagara International Airport (BUF)plane PQI - BUF
- Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus
9h 4m$173–994Bus
cheapest- Take the bus from Presque Isle, Maine to Bangor, MEbus
- Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus
- Take the bus from Boston to Syracuse Bus Stationbus
- Take the bus from Syracuse Bus Station to Niagara Falls USAbus
21h 1m$139–266Bus, train
- Take the bus from Presque Isle, Maine to Bangor, MEbus
- Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus
- Take the train from Boston to Buffalo Depew Stationtrain
- Take the train from Buffalo Depew Station to Niagara Falls Amtrak Stationtrain
23h 26m$169–521Drive 757.5 mi
- Drive from Presque Isle to Niagara Fallscar 757.5 mi
15h 43m$139–200Bus via Ithaca
- Take the bus from Presque Isle, Maine to Bangor, MEbus
- Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus
- Take the bus from Boston to Ithacabus
- Take the bus from Ithaca to Niagara Falls USAbus
22h 55m$151–291
Presque Isle to Niagara Falls by bus
Questions & Answers
The cheapest way to get from Presque Isle to Niagara Falls is to drive which costs $130 - $200 and takes 15h 43m.
The fastest way to get from Presque Isle to Niagara Falls is to fly and bus which takes 9h 4m and costs $170 - $1,000.
No, there is no direct bus from Presque Isle to Niagara Falls. However, there are services departing from Presque Isle, Maine and arriving at Niagara Falls USA via Bangor Transportation Center, Boston and Syracuse Bus Station. The journey, including transfers, takes approximately 21h 1m.
The distance between Presque Isle and Niagara Falls is 621 miles. The road distance is 762 miles.
The best way to get from Presque Isle to Niagara Falls without a car is to bus which takes 21h 1m and costs $130 - $270.
It takes approximately 9h 4m to get from Presque Isle to Niagara Falls, including transfers.
Presque Isle to Niagara Falls bus services, operated by Cyr Bus Line, depart from Presque Isle, Maine station.
Presque Isle to Niagara Falls bus services, operated by Cyr Bus Line, arrive at Bangor, ME station.
Yes, the driving distance between Presque Isle to Niagara Falls is 762 miles. It takes approximately 15h 43m to drive from Presque Isle to Niagara Falls.
There are 716+ hotels available in Niagara Falls.
What companies run services between Presque Isle, ME, USA and Niagara Falls, NY, USA?
You can take a bus from Presque Isle, Maine to Niagara Falls USA via Bangor, ME, Bangor Transportation Center, Boston, MA - South Station, Boston, and Syracuse Bus Station in around 21h 1m.
- Website
- jetblue.com
Flights from Presque Isle to Buffalo Niagara International Airport via Boston
- Ave. Duration
- 7h 11m
- When
- Monday and Thursday
- Estimated price
- $160–900
Flights from Presque Isle to Buffalo Niagara International Airport via Boston, New York JFK
- Ave. Duration
- 8h 16m
- When
- Monday
- Estimated price
- $170–950
- Website
- aa.com
Flights from Presque Isle to Buffalo Niagara International Airport via Boston
- Ave. Duration
- 7h 42m
- When
- Sunday
- Estimated price
- $160–900
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Buffalo Depew Station
- Ave. Duration
- 11h 39m
- Frequency
- Once daily
- Estimated price
- $90–340
- Website
- https://www.amtrak.com/home.html
Train from Buffalo Depew Station to Niagara Falls Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 3 times a day
- Estimated price
- $13–15
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888 842-7245
- Website
- viarail.ca
Train from Buffalo Depew Station to Niagara Falls Amtrak Station
- Ave. Duration
- 1h 23m
- Frequency
- Once daily
- Estimated price
- $13–80
- Website
- https://www.viarail.ca/en
- Economy Adult - same day booking
- $13–80
- Economy Adult - Advanced Booking
- $13–60
- Economy Escape Advanced Booking - Adult
- $13–25
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Buffalo Niagara International Airport to Niagara Falls USA
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- $6–85
- Schedules at
- flixbus.com
- Adult
- $6–85
Bus from Boston to Syracuse Bus Station
- Ave. Duration
- 6h 30m
- Frequency
- 5 times a week
- Estimated price
- $50–120
- Schedules at
- flixbus.com
Bus from Syracuse Bus Station to Niagara Falls USA
- Ave. Duration
- 3h 35m
- Frequency
- Every 4 hours
- Estimated price
- $28–45
- Schedules at
- flixbus.com
Bus from Boston to Ithaca
- Ave. Duration
- 7h 44m
- Frequency
- 5 times a week
- Estimated price
- $50–110
- Schedules at
- flixbus.com
Bus from Ithaca to Niagara Falls USA
- Ave. Duration
- 4h 25m
- Frequency
- Once daily
- Estimated price
- $35–80
- Schedules at
- flixbus.com
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Buffalo Niagara International Airport to Niagara Falls USA
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $20–50
- Website
- https://www.ourbus.com
- Phone
- +1 207-942-3354
- Website
- johntcyrandsons.com
Bus from Presque Isle, Maine to Bangor, ME
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $26–35
- Website
- http://johntcyrandsons.com
- Phone
- +1 800 639 3317
- info@concordcoachlines.com
- Website
- concordcoachlines.com
Bus from Bangor Transportation Center to Boston, MA - South Station
- Ave. Duration
- 4h 25m
- Frequency
- Every 4 hours
- Estimated price
- $50–70
- Website
- https://concordcoachlines.com
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Bangor Transportation Center to Boston, MA - South Station
- Ave. Duration
- 4h 25m
- Frequency
- 5 times a day
- Estimated price
- $43–48
- Website
- https://www.amtrak.com/home.html
- Adult
- $43–48
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Boston to Syracuse Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- Once daily
- Estimated price
- $45–120
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
What documents do I need to cross Niagara Falls?
Read the travel guide
Which side of Niagara Falls should I choose (and how do I get there)?
Read the travel guide
Travelling to the US: What do I need to know?
Read the travel guide















