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How to get fromPresque Isle to Hyannisby plane, bus (Amtrak), car, bus or train

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There are 5 ways to get from Presque Isle to Hyannis by plane, bus (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Barnstable Municipal Airport

    best
    1. Fly from Presque Isle (PQI) to Barnstable Municipal Airport (HYA)plane plane PQI - HYA
    5h 20m
    $67–369

  2. Bus

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus bus
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    11h 19m
    $93–136

  3. Drive 461.9 mi

    1. Drive from Presque Isle to Hyanniscar car 461.9 mi
    8h 8m
    $85–122

  4. Fly to Boston Logan Airport, bus

    1. Fly from Presque Isle (PQI) to Boston Logan Airport (BOS)plane plane PQI - BOS
    2. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    4h 28m
    $90–409

  5. Bus, train

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Portland Transportation Centerbus bus
    3. Take the train from Portland to Bostontrain train
    4. Take the bus from Boston South Station to Hyannis Transportation Centerbus bus
    12h 56m
    $97–157

Presque Isle to Hyannis by bus

Calendar7Weekly Buses
Duration11h 19mAverage Duration
Ticket$93Cheapest Price
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Questions & Answers

What companies run services between Presque Isle, ME, USA and Hyannis, MA, USA?

JetBlue Airways and Cape Air fly from Presque Isle (PQI) to Barnstable Municipal Airport (HYA) 3 times a day. Alternatively, you can take a bus from Presque Isle, Maine to Hyannis Transportation Center via Bangor, ME, Bangor Transportation Center, Boston, MA - South Station, and Boston South Buses in around 11h 19m.

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