There are 4 ways to get from Presque Isle to Buffalo by plane, bus (Amtrak, Flixbus, Greyhound), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Presque Isle (PQI) to Buffalo Niagara International Airport (BUF)PQI - BUF
5h 52m$211–1,289Bus
cheapest- Take the bus from Presque Isle, Maine to Bangor, ME
- Take the bus from Bangor Transportation Center to Boston, MA - South Station
- Take the bus from Boston to Syracuse Bus Station
- Take the bus from Syracuse Bus Station to Buffalo
20h 5m$136–276Bus, train
- Take the bus from Presque Isle, Maine to Bangor, ME
- Take the bus from Bangor Transportation Center to Boston, MA - South Station
- Take the train from Boston to Buffalo Depew Station
22h 46m$175–826Drive 753.6 mi
- Drive from Presque Isle to Buffalo753.6 mi
15h 12m$138–199
Presque Isle to Buffalo by bus
Questions & Answers
The cheapest way to get from Presque Isle to Buffalo is to drive which costs $130 - $200 and takes 15h 12m.
The fastest way to get from Presque Isle to Buffalo is to fly which takes 5h 52m and costs $210 - $1,300.
No, there is no direct bus from Presque Isle to Buffalo. However, there are services departing from Presque Isle, Maine and arriving at Buffalo via Bangor Transportation Center, Boston and Syracuse Bus Station. The journey, including transfers, takes approximately 20h 5m.
The distance between Presque Isle and Buffalo is 599 miles. The road distance is 758 miles.
The best way to get from Presque Isle to Buffalo without a car is to bus which takes 20h 5m and costs $130 - $280.
It takes approximately 5h 52m to get from Presque Isle to Buffalo, including transfers.
Presque Isle to Buffalo bus services, operated by Cyr Bus Line, depart from Presque Isle, Maine station.
The best way to get from Presque Isle to Buffalo is to fly which takes 5h 52m and costs $210 - $1,300. Alternatively, you can bus, which costs $130 - $280 and takes 20h 5m.
Presque Isle to Buffalo bus services, operated by Cyr Bus Line, arrive at Bangor, ME station.
Yes, the driving distance between Presque Isle to Buffalo is 758 miles. It takes approximately 15h 12m to drive from Presque Isle to Buffalo.
What companies run services between Presque Isle, ME, USA and Buffalo, NY, USA?
JetBlue Airways flies from Presque Isle (PQI) to Buffalo Niagara International Airport (BUF) once daily. Alternatively, you can take a bus from Presque Isle, Maine to Buffalo via Bangor, ME, Bangor Transportation Center, Boston, MA - South Station, Boston, and Syracuse Bus Station in around 20h 5m.
- Website
- jetblue.com
Flights from Presque Isle to Buffalo Niagara International Airport via Boston
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $200–1,200
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Buffalo Depew Station
- Ave. Duration
- 11h 39m
- Frequency
- Once daily
- Estimated price
- $100–650
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 207-942-3354
- Website
- johntcyrandsons.com
Bus from Presque Isle, Maine to Bangor, ME
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $26–35
- Website
- http://johntcyrandsons.com
- Phone
- +1 800 639 3317
- info@concordcoachlines.com
- Website
- concordcoachlines.com
Bus from Bangor Transportation Center to Boston, MA - South Station
- Ave. Duration
- 4h 25m
- Frequency
- Every 4 hours
- Estimated price
- $50–70
- Website
- https://concordcoachlines.com
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Bangor Transportation Center to Boston, MA - South Station
- Ave. Duration
- 4h 25m
- Frequency
- 5 times a day
- Estimated price
- $43–48
- Website
- https://www.amtrak.com/home.html
- Adult
- $43–48
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Boston to Syracuse Bus Station
- Ave. Duration
- 6h 35m
- Frequency
- 6 times a week
- Estimated price
- $45–120
- Schedules at
- flixbus.com
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 2h 55m
- Frequency
- Every 4 hours
- Estimated price
- $27–40
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Boston to Syracuse Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- Once daily
- Estimated price
- $45–130
- Website
- https://www.greyhound.com/
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h 20m
- Frequency
- 4 times a day
- Estimated price
- $27–45
- Website
- https://www.greyhound.com/
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h 10m
- Frequency
- 4 times a day
- Estimated price
- $25–40
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 217+ hotels available in Buffalo.