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How to get fromPrairie du Chien to St. Louisby car, bus, train or plane

Find Transport to St. Louis

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There are 7 ways to get from Prairie du Chien to St. Louis by car, bus, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, bus, train via Milwaukee

    best
    1. Drive from Prairie du Chien to UW La Crossecar car
    2. Take the bus from UW La Crosse to Milwaukeebus bus
    3. Take the train from Milwaukee to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to St. Louistrain train
    13h 18m
    $110–306

  2. Drive 378.3 mi

    cheapest
    1. Drive from Prairie du Chien to St. Louiscar car 378.3 mi
    7h 4m
    $69–100

  3. Drive, bus, train

    1. Drive from Prairie du Chien to La Crossecar car
    2. Take the bus from La Crosse to Madisonbus bus
    3. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    4. Take the train from Chicago Union Station to St. Louistrain train
    14h 10m
    $106–286

  4. Drive, bus to Minneapolis–Saint Paul International Airport, fly

    1. Drive from Prairie du Chien to La Crossecar car
    2. Take the bus from La Crosse to St. Paulbus bus
    3. Fly from Minneapolis–Saint Paul International Airport (MSP) to Lambert–St. Louis International Airport (STL)plane plane MSP - STL
    8h 23m
    $160–947

  5. Drive, bus

    1. Drive from Prairie du Chien to UW La Crossecar car
    2. Take the bus from UW La Crosse to Milwaukeebus bus
    3. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    15h 28m
    $76–203

  6. Drive, bus to General Mitchell International Airport, fly

    1. Drive from Prairie du Chien to UW La Crossecar car
    2. Take the bus from UW La Crosse to Milwaukeebus bus
    3. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    8h 41m
    $176–1,128

  7. Drive, bus, bus to Chicago O'Hare International Airport, fly

    1. Drive from Prairie du Chien to UW La Crossecar car
    2. Take the bus from UW La Crosse to Madisonbus bus
    3. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    4. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    10h 14m
    $297–734

Minneapolis–Saint Paul International Airport (MSP) to Lambert–St. Louis International Airport (STL) flights

Calendar60Weekly Planes
Duration1h 53mAverage Duration
Ticket$135Cheapest Price
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Questions & Answers

What companies run services between Prairie du Chien, WI, USA and St. Louis, MO, USA?

There is no direct connection from Prairie du Chien to St. Louis. However, you can drive to UW La Crosse, take the bus to Milwaukee, walk to Milwaukee, take the train to Chicago Union Station, then take the train to St. Louis. Alternatively, you can take a vehicle from Prairie du Chien to St. Louis via La Crosse, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, and Chicago Union Station in around 14h 10m.

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