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How to get fromPrague to Wetzlarby bus, train, car, or plane

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There are 7 ways to get from Prague to Wetzlar by bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Praha, ÚAN Florenc to Leipzig central train stationbus bus N67 / ...
    2. Take the bus from Leipzig central train station to Wetzlarbus bus N780
    9h 15m
    €53–83

  2. Train via Dresden

    1. Take the train from Praha Hlavni Nadrazi to Dresden Hbftrain train Rj
    2. Take the train from Dresden Hauptbahnhof to Kassel Bahnhof Wilhelmshöhetrain train 51
    3. Take the train from Kassel Bahnhof Wilhelmshöhe to Gießen Bahnhoftrain train
    10h
    €100–210

  3. Drive  512.1 km

    1. Drive from Prague to Wetzlarcar car 512.1 km
    5h 2m
    €93–133

  4. Fly from Václav Havel Airport Prague, train

    1. Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)plane plane PRG - FRA
    2. Take the train from Frankfurt to Gießen Bahnhoftrain train
    6h 37m
    €70–156

  5. Train

    1. Take the train from Praha Hlavni Nadrazi to Kassel-Wilhelmshoehetrain train Ec
    2. Take the train from Kassel Bahnhof Wilhelmshöhe to Gießen Bahnhoftrain train Re30
    11h 19m
    €162–182

  6. Bus, train

    1. Take the bus from Praha Hlavní nádraží to Frankfurt, Hauptbahnhof FOBbus bus Ivano-Frankivsk
    2. Take the train from Frankfurt to Gießen Bahnhoftrain train Re30
    19h 50m
    €134–152

  7. Train to Dresden Airport, fly, train

    1. Take the train from Praha Hlavni Nadrazi to Dresden Hbftrain train
    2. Fly from Dresden Airport (DRS) to Frankfurt (FRA)plane plane DRS - FRA
    3. Take the train from Frankfurt to Gießen Bahnhoftrain train
    8h 8m
    €154–373

Prague to Wetzlar by bus

Calendar5Weekly Buses
Duration9h 15mAverage Duration
Ticket€53Cheapest Price
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Comparing Your Travel Options

Map of how to get from Prague to Wetzlar.ExpandLaunch map view
  • Distance: 602.5 km
  • Duration: 9h 15m

What companies run services between Prague, Czechia and Wetzlar, Germany?

You can take a bus from Praha, ÚAN Florenc to Wetzlar via Leipzig central train station in around 9h 15m. Alternatively, you can take a train from Praha Hlavni Nadrazi to Wetzlar Bahnhof via Dresden Hauptbahnhof, Kassel Bahnhof Wilhelmshöhe, and Gießen Bahnhof in around 10h.

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