There are 8 ways to get from Prague to Wetzlar by bus, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Praha, ÚAN Florenc to Leipzig central train stationbus N67 / ...
- Take the bus from Leipzig central train station to Wetzlarbus N780
9h 15m€53–78Train via Dresden
- Take the train from Praha-Holesovice to Dresden Hbftrain Rj
- Take the train from Dresden Hauptbahnhof to Kassel Bahnhof Wilhelmshöhetrain 51
- Take the train from Kassel Bahnhof Wilhelmshöhe to Gießen Bahnhoftrain
9h 49m€104–309Drive 512.1 km
- Drive from Prague to Wetzlarcar 512.1 km
5h 2m€81–118Fly Václav Havel Airport Prague to Frankfurt, train
- Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)plane PRG - FRA
- Take the train from Frankfurt to Gießen Bahnhoftrain
6h 36m€72–184Train
- Take the train from Praha Hlavni Nadrazi to Kassel-Wilhelmshoehetrain Ec
- Take the train from Kassel Bahnhof Wilhelmshöhe to Gießen Bahnhoftrain Re30
11h 19m€151–246Bus, train
- Take the bus from Praha Hlavní nádraží to Frankfurt, Hauptbahnhof FOBbus Ivano-Frankivsk
- Take the train from Frankfurt to Gießen Bahnhoftrain Re30
19h 50m€136–183Train to Dresden Airport, fly to Frankfurt, train
- Take the train from Praha-Holesovice to Dresden Hbftrain
- Fly from Dresden Airport (DRS) to Frankfurt (FRA)plane DRS - FRA
- Take the train from Frankfurt to Gießen Bahnhoftrain
7h 57m€152–421Fly Václav Havel Airport Prague to Cologne Bonn Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Cologne Bonn Airport (CGN)plane PRG - CGN
- Take the train from Flughafen Köln/Bonn Bf to Limburgtrain
- Take the train from Limburg to Wetzlar Bahnhoftrain
7h 32m€103–314
Prague to Wetzlar by bus
Comparing Your Travel Options
The cheapest way to get from Prague to Wetzlar is to bus which costs €50 - €80 and takes 9h 15m.
The fastest way to get from Prague to Wetzlar is to drive which takes 5h 2m and costs €80 - €120.
No, there is no direct bus from Prague to Wetzlar. However, there are services departing from Praha, ÚAN Florenc and arriving at Wetzlar via Leipzig central train station. The journey, including transfers, takes approximately 9h 15m.
No, there is no direct train from Prague to Wetzlar. However, there are services departing from Praha-Holesovice and arriving at Wetzlar Bahnhof via Dresden Hauptbahnhof, Kassel Bahnhof Wilhelmshöhe and Gießen Bahnhof. The journey, including transfers, takes approximately 9h 49m.
The distance between Prague and Wetzlar is 603 km. The road distance is 512.1 km.
The best way to get from Prague to Wetzlar without a car is to bus which takes 9h 15m and costs €50 - €80.
It takes approximately 9h 15m to get from Prague to Wetzlar, including transfers.
Prague to Wetzlar bus services, operated by FlixBus, depart from Praha, ÚAN Florenc station.
Prague to Wetzlar train services, operated by České dráhy (ČD), depart from Praha-Holesovice station.
The best way to get from Prague to Wetzlar is to bus which takes 9h 15m and costs €50 - €80. Alternatively, you can train via Dresden, which costs €100 - €310 and takes 9h 49m.
What companies run services between Prague, Czechia and Wetzlar, Germany?
You can take a bus from Praha, ÚAN Florenc to Wetzlar via Leipzig central train station in around 9h 15m. Alternatively, you can take a train from Praha-Holesovice to Wetzlar Bahnhof via Dresden Hauptbahnhof, Kassel Bahnhof Wilhelmshöhe, and Gießen Bahnhof in around 9h 49m.
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €60–370
Flights from Václav Havel Airport Prague to Frankfurt via Munich
- Ave. Duration
- 2h 50m
- When
- Every day
- Estimated price
- €60–140
Flights from Dresden Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €45–340
Flights from Václav Havel Airport Prague to Cologne Bonn Airport via Munich
- Ave. Duration
- 3h 2m
- When
- Every day
- Estimated price
- €85–260
- Website
- condor.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 8m
- When
- Every day
- Estimated price
- €55–110
- Website
- airdolomiti.it
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €120–370
- Website
- lufthansa-city.com
Flights from Dresden Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Monday
- Estimated price
- €45–340
- Website
- eurowings.com
Flights from Václav Havel Airport Prague to Cologne Bonn Airport
- Ave. Duration
- 1h 15m
- When
- Friday and Sunday
- Estimated price
- €75–220
- Website
- austrian.com
Flights from Václav Havel Airport Prague to Cologne Bonn Airport via Vienna
- Ave. Duration
- 3h 15m
- When
- Monday to Thursday
- Estimated price
- €75–220
- Phone
- +420 221 111 122
- info@cd.cz
- Website
- Czech Railways (ČD)
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 7m
- Frequency
- Every 4 hours
- Estimated price
- €17–25
- Website
- Czech Railways (ČD)
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 7m
- Frequency
- Every 4 hours
- Estimated price
- €17–25
- Website
- Czech Railways (ČD)
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 17m
- Frequency
- 3 times a day
- Estimated price
- €40–50
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Kassel-Wilhelmshoehe
- Ave. Duration
- 7h 50m
- Frequency
- Once daily
- Estimated price
- €120–150
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 17m
- Frequency
- 3 times a day
- Estimated price
- €40–50
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
- Phone
- +43 (0)5 1717
- Website
- Railjet
Train from Praha-Holesovice to Dresden Hbf
- *
- €30–45
Train from Praha-Holesovice to Dresden Hbf
- *
- €30–45
- Phone
- +47 70 13 14 15
- kundehenv@dsb.dk
- Website
- Danish Railways
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 9m
- Frequency
- Twice daily
- Estimated price
- €15
- Website
- Danish Railways
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 9m
- Frequency
- Twice daily
- Estimated price
- €15
- Website
- Danish Railways
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Dresden Hauptbahnhof to Kassel Bahnhof Wilhelmshöhe
- Ave. Duration
- 3h 22m
- Frequency
- Twice daily
- Estimated price
- €65–150
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Kassel Bahnhof Wilhelmshöhe to Gießen Bahnhof
- Ave. Duration
- 1h 16m
- Frequency
- 4 times a day
- Estimated price
- €22–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Gießen Bahnhof
- Ave. Duration
- 40 min
- Frequency
- Twice a week
- Estimated price
- €11–25
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Kassel Bahnhof Wilhelmshöhe to Gießen Bahnhof
- Ave. Duration
- 1h 16m
- Frequency
- 4 times a day
- Estimated price
- €22–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Gießen Bahnhof
- Ave. Duration
- 40 min
- Frequency
- Twice a week
- Estimated price
- €11–25
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Gießen Bahnhof
- Ave. Duration
- 40 min
- Frequency
- Twice a week
- Estimated price
- €11–25
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Flughafen Köln/Bonn Bf to Limburg
- Ave. Duration
- 44 min
- Frequency
- 3 times a day
- Estimated price
- €17–40
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Kassel Bahnhof Wilhelmshöhe to Gießen Bahnhof
- Ave. Duration
- 1h 23m
- Frequency
- Every 2 hours
- Estimated price
- €24–100
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Frankfurt to Gießen Bahnhof
- Ave. Duration
- 42 min
- Frequency
- Hourly
- Estimated price
- €12–50
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Kassel Bahnhof Wilhelmshöhe to Gießen Bahnhof
- Ave. Duration
- 1h 23m
- Frequency
- Every 2 hours
- Estimated price
- €24–100
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Frankfurt to Gießen Bahnhof
- Ave. Duration
- 42 min
- Frequency
- Hourly
- Estimated price
- €12–50
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Frankfurt to Gießen Bahnhof
- Ave. Duration
- 42 min
- Frequency
- Hourly
- Estimated price
- €12–50
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Limburg to Wetzlar Bahnhof
- Ave. Duration
- 41 min
- Frequency
- Every 4 hours
- Estimated price
- €9–40
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Praha, ÚAN Florenc to Leipzig central train station
- Ave. Duration
- 3h 45m
- Frequency
- Every 4 hours
- Estimated price
- €22–35
- Website
- Flixbus
Bus from Leipzig central train station to Wetzlar
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a week
- Estimated price
- €30–45
- Website
- Flixbus
- Phone
- +38 098-888-11-08
- igoruzhanskyi@grandbus.com.ua
- Website
- Grand Bus
Bus from Praha Hlavní nádraží to Frankfurt, Hauptbahnhof FOB
- Ave. Duration
- 16h 56m
- Frequency
- Once daily
- Estimated price
- €120–135
- Website
- Grand Bus
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Booking & Getting There
Prague to Wetzlar bus services, operated by FlixBus, arrive at Leipzig central train station.
Prague to Wetzlar train services, operated by České dráhy (ČD), arrive at Dresden Hbf station.
Yes, the driving distance between Prague to Wetzlar is 512 km. It takes approximately 5h 2m to drive from Prague to Wetzlar.
Book your Prague to Wetzlar train tickets online with Omio.
Book your Prague to Wetzlar bus tickets online with Omio and FlixBus.
There are 489+ hotels available in Wetzlar.
































