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How to get fromPrague to Palermoby plane, train (Trenitalia), bus, car, ferry, shuttle, train or night train

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There are 9 ways to get from Prague to Palermo by plane, train (Trenitalia), bus, car, ferry, shuttle, train, or night train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Václav Havel Airport Prague to Palermo Airport

    best
    1. Fly from Václav Havel Airport Prague (PRG) to Palermo Airport (PMO)plane plane PRG - PMO
    7h 15m
    €65–320
  2. Train

    1. Take the train from Praha Hlavni Nadrazi to Muenchen Hbftrain train Ec
    2. Take the train from München Hbf to Verona Porta Nuovatrain train 89
    3. Take the train from Verona Porta Nuova to Roma Terminitrain train Fr
    4. Take the train from Roma Termini to Palermo Centraletrain train Ic
    29h 19m
    €203–427
  3. Bus

    1. Take the bus from Praha, ÚAN Florenc to Bologna Centralebus bus N538 / ...
    2. Take the bus from Bologna Centrale to Palermobus bus N597
    32h 50m
    €66–209
  4. Drive, ferry

    1. Drive from Prague to Port of Naplescar car
    2. Take the ferry from Port of Naples to Port of Palermoferry ferry
    22h 51m
    €261–374
  5. Fly Václav Havel Airport Prague to Trapani Airport, shuttle

    1. Fly from Václav Havel Airport Prague (PRG) to Trapani Airport (TPS)plane plane PRG - TPS
    2. Take a shuttle bus from Trapani Birgi Airport to Lazio Municipioshuttle bus
    10h 55m
    €83–305
  6. Fly Václav Havel Airport Prague to Catania–Fontanarossa Airport, bus

    1. Fly from Václav Havel Airport Prague (PRG) to Catania–Fontanarossa Airport (CTA)plane plane PRG - CTA
    2. Take the bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazellobus bus
    7h 49m
    €71–253
  7. Train to Munich International Airport, fly to Palermo Airport

    1. Take the train from Praha Hlavni Nadrazi to Freisingtrain train
    2. Fly from Munich International Airport (MUC) to Palermo Airport (PMO)plane plane MUC - PMO
    10h 41m
    €156–390
  8. Train, night train

    1. Take the train from Praha Hlavni Nadrazi to Linz Hbftrain train Ec
    2. Take the night train from Linz Hbf to Venezia Mestrenighttrain night train Nj
    3. Take the train from Venezia Mestre to Roma Terminitrain train Fr
    4. Take the train from Roma Termini to Palermo Centraletrain train Ic
    31h 29m
    €110–524
  9. Train, bus

    1. Take the train from Prague Main Train Station to Brno Main Train Stationtrain train
    2. Take the bus from Brno Benesova Bus Station to Roma, Autostazione Tiburtinabus bus
    3. Take the bus from Roma, Autostazione Tiburtina to Palermo Terminal Busbus bus
    35h 10m
    €116–167

Prague to Palermo by train

Calendar8Weekly Trains
Duration29h 19mAverage Duration
Ticket€203Cheapest Price
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Questions & Answers

What companies run services between Prague, Czechia and Palermo, Italy?

Lufthansa, Air Dolomiti, and five other airlines fly from Václav Havel Airport Prague (PRG) to Palermo Airport (PMO) once daily. Alternatively, you can take a train from Praha Hlavni Nadrazi to Palermo Centrale via Muenchen Hbf, München Hbf, Verona Porta Nuova, and Roma Termini in around 29h 19m.

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