There are 9 ways to get from Prague to Palermo by plane, train (Trenitalia), bus, car, ferry, shuttle, train, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Václav Havel Airport Prague to Palermo Airport
best- Fly from Václav Havel Airport Prague (PRG) to Palermo Airport (PMO)plane PRG - PMO
7h 15m€65–320Train
- Take the train from Praha Hlavni Nadrazi to Muenchen Hbftrain Ec
- Take the train from München Hbf to Verona Porta Nuovatrain 89
- Take the train from Verona Porta Nuova to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
29h 19m€203–427Bus
- Take the bus from Praha, ÚAN Florenc to Bologna Centralebus N538 / ...
- Take the bus from Bologna Centrale to Palermobus N597
32h 50m€66–209Drive, ferry
- Drive from Prague to Port of Naplescar
- Take the ferry from Port of Naples to Port of Palermoferry
22h 51m€261–374Fly Václav Havel Airport Prague to Trapani Airport, shuttle
- Fly from Václav Havel Airport Prague (PRG) to Trapani Airport (TPS)plane PRG - TPS
- Take a shuttle bus from Trapani Birgi Airport to Lazio Municipio
10h 55m€83–305Fly Václav Havel Airport Prague to Catania–Fontanarossa Airport, bus
- Fly from Václav Havel Airport Prague (PRG) to Catania–Fontanarossa Airport (CTA)plane PRG - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazellobus
7h 49m€71–253Train to Munich International Airport, fly to Palermo Airport
- Take the train from Praha Hlavni Nadrazi to Freisingtrain
- Fly from Munich International Airport (MUC) to Palermo Airport (PMO)plane MUC - PMO
10h 41m€156–390Train, night train
- Take the train from Praha Hlavni Nadrazi to Linz Hbftrain Ec
- Take the night train from Linz Hbf to Venezia Mestrenighttrain Nj
- Take the train from Venezia Mestre to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
31h 29m€110–524Train, bus
- Take the train from Prague Main Train Station to Brno Main Train Stationtrain
- Take the bus from Brno Benesova Bus Station to Roma, Autostazione Tiburtinabus
- Take the bus from Roma, Autostazione Tiburtina to Palermo Terminal Busbus
35h 10m€116–167
Prague to Palermo by train
Questions & Answers
The cheapest way to get from Prague to Palermo is to fly and bus which costs €70 - €260 and takes 7h 49m.
The fastest way to get from Prague to Palermo is to fly which takes 7h 15m and costs €65 - €320.
No, there is no direct bus from Prague to Palermo. However, there are services departing from Praha, ÚAN Florenc and arriving at Palermo via Bologna Centrale. The journey, including transfers, takes approximately 32h 50m.
No, there is no direct train from Prague to Palermo. However, there are services departing from Praha Hlavni Nadrazi and arriving at Palermo Centrale via München Hbf, Verona Porta Nuova and Roma Termini. The journey, including transfers, takes approximately 29h 19m.
The distance between Prague and Palermo is 1374 km.
The best way to get from Prague to Palermo without a car is to train which takes 29h 19m and costs €200 - €430.
It takes approximately 7h 15m to get from Prague to Palermo, including transfers.
Prague to Palermo bus services, operated by FlixBus, depart from Praha, ÚAN Florenc station.
Prague to Palermo train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Palermo is to fly which takes 7h 15m and costs €65 - €320. Alternatively, you can train, which costs €200 - €430 and takes 29h 19m, you could also bus, which costs €65 - €210 and takes 32h 50m.
What companies run services between Prague, Czechia and Palermo, Italy?
Lufthansa, Air Dolomiti, and five other airlines fly from Václav Havel Airport Prague (PRG) to Palermo Airport (PMO) once daily. Alternatively, you can take a train from Praha Hlavni Nadrazi to Palermo Centrale via Muenchen Hbf, München Hbf, Verona Porta Nuova, and Roma Termini in around 29h 19m.
- Website
- ryanair.com
Flights from Václav Havel Airport Prague to Palermo Airport via Naples
- Ave. Duration
- 5h 40m
- When
- Saturday
- Estimated price
- €55–350
Flights from Václav Havel Airport Prague to Palermo Airport via Vienna
- Ave. Duration
- 5h 25m
- When
- Monday
- Estimated price
- €55–350
Flights from Václav Havel Airport Prague to Palermo Airport via Verona
- Ave. Duration
- 6h 45m
- When
- Friday
- Estimated price
- €55–350
Flights from Václav Havel Airport Prague to Trapani Airport via Milan Bergamo
- Ave. Duration
- 7h 17m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €70–290
Flights from Václav Havel Airport Prague to Trapani Airport via Pisa
- Ave. Duration
- 8h 40m
- When
- Monday
- Estimated price
- €70–290
Flights from Václav Havel Airport Prague to Trapani Airport via Bari
- Ave. Duration
- 11h 25m
- When
- Monday
- Estimated price
- €70–290
Flights from Václav Havel Airport Prague to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 30m
- When
- Tuesday and Saturday
- Estimated price
- €60–240
- Website
- ita-airways.com
Flights from Václav Havel Airport Prague to Palermo Airport via Munich International Airport
- Ave. Duration
- 5h 5m
- When
- Saturday and Sunday
- Estimated price
- €75–300
Flights from Munich International Airport to Palermo Airport
- Ave. Duration
- 2h
- When
- Saturday and Sunday
- Estimated price
- €110–350
Flights from Munich International Airport to Palermo Airport via Rome
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- €75–280
Flights from Munich International Airport to Palermo Airport via Milan Linate
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- €75–280
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Palermo Airport via Munich International Airport
- Ave. Duration
- 4h 25m
- When
- Saturday and Sunday
- Estimated price
- €75–340
Flights from Munich International Airport to Palermo Airport
- Ave. Duration
- 2h
- When
- Saturday and Sunday
- Estimated price
- €110–350
Flights from Munich International Airport to Palermo Airport via Rome
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- €160–260
- Website
- easyjet.com
Flights from Václav Havel Airport Prague to Palermo Airport via Naples
- Ave. Duration
- 8h 15m
- When
- Friday and Sunday
- Estimated price
- €40–200
- Website
- austrian.com
Flights from Václav Havel Airport Prague to Palermo Airport via Vienna
- Ave. Duration
- 8h 15m
- When
- Saturday
- Estimated price
- €70–300
- Website
- tuifly.be
Flights from Václav Havel Airport Prague to Palermo Airport via Naples
- Ave. Duration
- 6h 15m
- When
- Friday
- Estimated price
- €40–200
- Website
- flyulendo.com
Flights from Václav Havel Airport Prague to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 30m
- When
- Tuesday and Saturday
- Estimated price
- €55–160
- Website
- smartwings.com
Flights from Václav Havel Airport Prague to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 15m
- When
- Wednesday and Sunday
- Estimated price
- €120–210
- Website
- airdolomiti.it
Flights from Munich International Airport to Palermo Airport
- Ave. Duration
- 2h
- When
- Sunday
- Estimated price
- €110–350
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Praha Hlavni Nadrazi to Muenchen Hbf
- Ave. Duration
- 5h 43m
- Frequency
- Every 4 hours
- Estimated price
- €75–100
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Praha Hlavni Nadrazi to Freising
- Ave. Duration
- 5h 15m
- Frequency
- Every 4 hours
- Estimated price
- €70–90
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Praha Hlavni Nadrazi to Linz Hbf
- Ave. Duration
- 3h 45m
- Frequency
- 4 times a day
- Estimated price
- €19–45
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from München Hbf to Verona Porta Nuova
- Ave. Duration
- 5h 29m
- Frequency
- Every 4 hours
- Estimated price
- €65–120
- Website
- https://int.bahn.de/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Verona Porta Nuova to Roma Termini
- Ave. Duration
- 3h 23m
- Frequency
- Every 4 hours
- Estimated price
- €35–100
- Schedules at
- trenitalia.com
Train from Venezia Mestre to Roma Termini
- Ave. Duration
- 3h 47m
- Frequency
- Hourly
- Estimated price
- €35–100
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 44m
- Frequency
- Once daily
- Estimated price
- €27–110
- Website
- https://www.trenitalia.com/en.html
Train from Venezia Mestre to Roma Termini
- Ave. Duration
- 7h 40m
- Frequency
- Twice daily
- Estimated price
- €19–60
- Website
- https://www.trenitalia.com/en.html
- Phone
- +420 221 111 122
- info@cd.cz
- Website
- cd.cz
Train from Praha Hlavni Nadrazi to Linz Hbf
- Ave. Duration
- 5h 53m
- Frequency
- Once daily
- Estimated price
- €12–28
- Website
- https://www.cd.cz/en/default.htm
- Phone
- +43 51717
- Website
- nightjet.com
Night train from Linz Hbf to Venezia Mestre
- Ave. Duration
- 9h 13m
- Frequency
- Once daily
- Estimated price
- €50–264
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €259–264
- Couchette Carriage
- €140–160
- Seating Carriage
- €50–65
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Venezia Mestre to Roma Termini
- Ave. Duration
- 3h 48m
- Frequency
- Every 3 hours
- Estimated price
- €40–95
- Website
- https://www.italotreno.it/en
- Phone
- +420 222 222 221
- info@regiojet.cz
- Website
- regiojet.com
Train from Prague Main Train Station to Brno Main Train Station
- Ave. Duration
- 2h 36m
- Frequency
- Every 3 hours
- Estimated price
- €6–17
- Website
- https://regiojet.com/
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Praha, ÚAN Florenc to Bologna Centrale
- Ave. Duration
- 13h 15m
- Frequency
- Twice daily
- Estimated price
- €40–100
- Website
- https://www.flixbus.co.uk
Bus from Bologna Centrale to Palermo
- Ave. Duration
- 18h 35m
- Frequency
- Once daily
- Estimated price
- €30–110
- Website
- https://www.flixbus.co.uk
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 2h 35m
- Frequency
- Twice daily
- Estimated price
- €9–19
- Website
- https://www.flixbus.co.uk
- Phone
- +420 222 222 221
- info@regiojet.cz
- Website
- regiojet.com
Bus from Praha, ÚAN Florenc to Bologna Centrale
- Ave. Duration
- 14h 45m
- Frequency
- Once a week
- Estimated price
- €35–80
- Website
- https://regiojet.com/
Bus from Brno Benesova Bus Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 17h 15m
- Frequency
- Once a week
- Estimated price
- €55–90
- Website
- https://regiojet.com/
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Bologna Centrale to Palermo
- Ave. Duration
- 17h 15m
- Frequency
- Twice a week
- Estimated price
- €50–75
- Schedules at
- autoservizisalemi.it
- customerservices@terravision.eu
- Website
- terravision.eu
Shuttle from Trapani Birgi Airport to Lazio Municipio
- Ave. Duration
- 1h 38m
- Frequency
- Every 4 hours
- Estimated price
- €11
- Website
- https://www.terravision.eu/
- Phone
- 800 21 10 20
- saisautolineeweb@gmail.com
- Website
- saisautolinee.it
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 2h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Schedules at
- saisautolinee.it
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Roma, Autostazione Tiburtina to Palermo Terminal Bus
- Ave. Duration
- 13h 15m
- Frequency
- 3 times a week
- Estimated price
- €55–60
- Website
- https://www.itabus.it/en/home
- Phone
- +39.081.496.444
- info@grimaldi.napoli.it
- Website
- grimaldi-lines.com
Ferry from Port of Naples to Port of Palermo
- Ave. Duration
- 8h 30m
- Frequency
- Once daily
- Estimated price
- €40–55
- Website
- https://www.grimaldi-lines.com/en/
Want to know more about travelling around Italy
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More Questions & Answers
Prague to Palermo bus services, operated by FlixBus, arrive at Bologna Centrale station.
Prague to Palermo train services, operated by ÖBB EuroCity, arrive at Muenchen Hbf station.
Book your Prague to Palermo train tickets online with Omio.
Book your Prague to Palermo bus tickets online with Omio and FlixBus.
There are 5728+ hotels available in Palermo.

























































